Staphylococcus aureus infections methicillin-resistant

Sotozono C, Inagaki K, Fujita A, et al. Methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus epidermidis infections in the cornea. Cornea 2002 21 S94-S101. [Pg.220]

Most appropriate use is when vancomycin-resistant Enterococcus faecium infection is documented or strongly suspected, or for oral therapy of methicillin-resistant Staphylococcus aureus infection... [Pg.700]

Klevens RM, Morrison MA, Nadle J et al. (2007) Invasive methicillin-resistant Staphylococcus aureus infections in the United States. JAMA 298 1763-1771... [Pg.211]

Stevens DL, Herr D, Lampiris H, et al, and the Linezolid MRSA Study 44. Group. Linezolid versus vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections. Clin Infect Dis 2002 34 45. [Pg.1994]

Fallon, M.T., Shafer, W., Jacob, E., 1999. Use of cefazolin microspheres to treat localized methicillin-resistant Staphylococcus aureus infections in rats. Journal of Surgical Research 86 (1), 97-102. [Pg.67]

Klevens RM, Morrison MA, Nadie J, Petit S, Geshman K, Ray S, Harrison LH, Lynefield R, Dumyati G, Townes JM, Craig AS, Zell ER, Fosheim GE, McDougal LK, Carey RB, Fridkin SK (2007) Invasive Methicillin-Resistant Staphylococcus aureus Infections in the United States. J Am Med Assoc 298 1763. [Pg.267]

KLEVENS R M, MORRISON M A, NADLE J, PETIT S, GERSHMAN K, RAY S, HARRISON L H, LYN-FIELD R, DUMYATI G, TOWNES J M, CRAIG A S, ZELL E R, FOSHEIM G E, MCDOUGAL L K, CAREY R B and FRiDKiN s K (2007) Invasive methicillin-resistant Staphylococcus aureus infections in the United States, 7 ybn Med Assoc, 298,1763-1771. [Pg.279]

Prcxluced by Pseudomotuu /luorescens Smith-Kline Beecham product, Bactroban Nasal, was approved in 1996 as a topical ointment for treatment of nasal methicillin resistant Staphylococcus aureus infections. [Pg.34]

Hiramatsu K, Ito T, Tsubakishita S, Sasaki T, Takeuchi F, Morimoto Y, Katayama Y, Matsuo M, Kuwahara-Arai K, Hishinuma T, Baba T. Genomic basis for methicillin resistance in Staphylococcus aureus. Infect Chemother. 2013 45(2) 117-36. doi 10.3947/ic.2013.45.2.117. [Pg.228]

Some of the most clinical significant bacteria involved in drug-resistant infections include (Table 6.1) Acinetobacter baumannii, P aeruginosa, Escherichia coli and Klebsiella pneumoniae resistant to j lactamases, along with methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Staphylococcus aureus (VRSA), and Mycobacterium tuberculosis. (Alekshun and Levy 2(X)7 Lee et al. 2008 Ojha et al. 2008 Weigel et al. 2007). Resistance mechanisms allow bacteria... [Pg.186]

Duckworth G, Cookson B, Humphreys H, et al. Revised guidelines for the control of methicillin-resistant Staphylococcus aureus infection in hospitals. J Hosp Infect 1998 39(4) 253-90. [Pg.159]

Liu, C., et al. Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin. Infect. Dis. 52(3), el8-55 (2011) (ciql46)... [Pg.90]

Methicillin has lost its clinical significance due to the high incidence of resistant Staphylococcus aureus infections. The use of heterocyclic substituents, based on isoxazolyl, led to the development of the penicillins cloxacillin and fiucloxacillin (Fig. 22.12). [Pg.454]

Infections acquired from an external source are referred to as exogenous infections. These infections may occur as a result of human-to-human transmission, contact with exogenous bacterial populations in the environment, and animal contact. Resistant pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus spp. [Pg.1021]

Methicillin-resistant Staphylococcus aureus (MRSA) is a common hospital-acquired pathogen and is also increasing in the community. MRSA has presented a problem in the past because it required treatment with vancomycin. Community-acquired MRSA presents a major therapeutic challenge. MRSA can cause pneumonia, cellulitis, and other infections. Clinicians should be aware of the rate of hospital and community MRSA in your geographic area. New treatment options are available for MRSA. They include linezolid, tigecycline, and daptomycin. Prospective clinical trials have not demonstrated benefits of these agents over vancomycin.36-37... [Pg.1192]

Reduce Methicillin-Resistant Staphylococcus aureus (MRSA) infection... by reliably implementing scientifically proven infection control practices... [Pg.94]

The bacterium Staphylococcus aureus, which is a major cause of infection in the developed countries, is now resistant to most antibiotics. It is usually present on the skin, where it causes no problems, but it can invade the body through cuts and wounds, including those caused by surgery. These bacteria are now prevalent in many hospitals, so that infection is a major problem for the medical staff in hospitals. The resistant bacterium is known as methicillin-resistant Staphylococcus aureus (MRSA). It is also known in the mass media as the super bug . Penicillin kiUs bacteria because the P-lactam group in the antibiotic inhibits a reaction that is essential for bacterial ceU wall production. Consequently, the bacteria cannot proliferate. Resistance to penicillin in many bacteria is due to production of an enzyme, p-lactamase, that degrades P-lactams. The antibiotic methicillin is one of a group of semisynthetic penicillins in which the P-lactam group is not... [Pg.410]

Yun HC, Ellis MW, Jorgensen JH. (2007) Activity of ceftobiprole against community-associated methicillin-resistant Staphylococcus Aureus isolates recently recovered from US military trainees. Diagn Microbiol Infect Dis 59 463-466. [Pg.177]

Widmer AF. (2008) Ceftobiprole A new option for treatment of skin and soft-tissue infections due to methicillin-resistant Staphylococcus Aureus. Clin Infect Dis 46 656-658. [Pg.177]

An additional disadvantage with many penicillin and cephalosporin antibiotics is that bacteria have developed resistance to the drugs by producing enzymes capable of hydrolysing the P-lactam ring these enzymes are called P-lactamases. This type of resistance still poses serious problems. Indeed, methicillin is no longer used, and antibiotic-resistant strains of the most common infective bacterium Staphylococcus aureus are commonly referred to as MRSA (methicillin-resistant Staphylococcus aureus). The action of P-lactamase enzymes resembles simple base hydrolysis of an amide. [Pg.266]

Some of the organotin-containing polymers inhibit Candias albicans, the yeast responsible for infections in humans better than commercially available applications while leaving the normal flora unharmed. Others inhibit methicillin-resistant Staphylococcus aureus (MRSA) (structure 11.22), preferentially. [Pg.370]

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