Acinetobacter baumannii

Chaiyen P, C Suadee, P Wilairat (2001) A novel two-protein component flavoprotein hydroxylase / -hydroxyphenylacetate from Acinetobacter baumannii. Eur J Biochem 268 5550-5561. 

Aeromonas hydrophila, Comamonas testosterone, Acinetobacter baumannii Red rbn Fluidized bed Continuous... 

Standard and the isolated strains of the following bacteria, namely Escherichia coli (ATCC 35218), Pseudomonas aeruginosa (ATCC 10145), Proteus mirabilis (ATCC 7002), Klebsiella pneumoniae (RSKK 574), Acinetobacter baumannii (RSKK 02026), Staphylococcus aureus (ATCC 25923), and Enterococcus faecalis (ATCC 29212) for determination of antibacterial activity, along with standard strains of Candida albicans (ATCC 10231) and C. parapsilosis (ATCC 22019) were used for determination of antifungal activity. 

Yamamoto S, Okujo N, Sakakibara Y (1994) Isolation and Structure Elucidation of Acinetobactin, a Novel Siderophore from Acinetobacter baumannii. Arch Mikrobiol 162 249... 

Due to the fact that Raman spectroscopy is a very sensitive technique, even identification on the strain level becomes possible. Various studies were performed distinguishing different strains of Acinetobacter baumannii [48], Staph, cohnii, and Staph, epidermidis strains [44], as well as various Bacillus strains [45]. Goeller et al. applied Raman spectroscopy not only to discriminate... 

OPS of Acinetobacter baumannii 024 (23) is a heteropolysaccharide that contains a 5-tV-acetyl derivative of legionaminic acid in about half of its tetrasaccharide repeating units and a S-iV-IXXi-S-hydroxybutanoyl] derivative in the remaining units35 (Fig. 6). 

Alkaloids Escherichia coli Pseudomonas aeruginosa Proteus mirabilis Klebsiella pneumoniae Acinetobacter baumannii Staphylococcus aureus Bacillus subtilis Candida albicans... 

Kim HU, Kim TY, Lee SY (2010) Genome-scale metabolic network analysis and drug targeting of multi-drug resistant pathogen Acinetobacter baumannii AYE. Mol Biosyst 6 339-348... 

Vinogradov, E.V., Duus, J., Brade, H., Holst, O. The structure of the carbohydrate backbone of the Lipopolysaccharide from Acinetobacter baumannii strain ATCC 19606. Eur J Biochem 269 (2002a) 422-430. 

Adams, M., Nickel, G., Bajaksouzian, S., Lavender, H., Murthy, A., Jacobs, M., Bonomo, R. Resistance to colistin in Acinetobacter baumannii associated with mutations in the PmrAB two-component system. Antimicro Agents Chemother 53 (2009) 3628-3634. 

H. parainfluenzae (MIC, 0.03-0.25 mg I. ) [150], M. catarrhalis (MIC90 0.03-0.125 mg L"1) [149,151,182] and K. pneumoniae [33,182,187,188], although its activity against specific bacteria is less powerful than that of ciprofloxacin [188]. When moxifloxacin was used in combination with cefepime or piperacilhn/tazobactam against clinical isolates of K. pneumoniae, Enterobacter cloacae and Acinetobacter baumannii, an increase in bactericidal activity was obtained compared to that of the individual compounds this was due to synergistic effects between the different compounds [189]. 

Jung R, et al. Synergistic activities of moxifloxacin combined with piperacil-lin-tazobactam or cefepime against Klebsiella pneumoniae, Enterobacter cloacae, and Acinetobacter baumannii clinical isolates. Antimicrob. Agents Chemother., 2004, 48, 1055-1057. 

AdeA/AdeB/AdeC RND Acinetobacter baumannii Aminoglycosides, chloramphenicol, fluoroquinolones, tetracycline, trimethroprim... 

This enzyme system, which has been isolated from several different organisms, subdivides into two distinct groups. The enzyme system from Acinetobacter baumannii is a model for one group, and the enzyme system from Pseudomonas aeruginosa is a model for the other. The P. aeruginosa hydroxylase is very similar to HPAH from E. coli (25), but it is more amenable for mechanistic studies. 

Sucharitakul J, Chaiyen P, Entsch B, Ballou DP. Kinetic mechanisms of the oxygenase from a two-component enzyme, p-hydroxy phenylacetate 3-hydroxylase from Acinetobacter baumannii. J. Biol. Chem. 2006 281 17044-17053. 

In Spain, an epidemic strain of Acinetobacter baumannii with resistance to amikacin was isolated in eight different hospitals (11). 

Vila J, Ruiz J, Navia M, Becerril B, Garcia I, Perea S, Lopez-Hernandez I, Alamo I, Ballester F, Planes AM, Martinez-Beltran J, de Anta TJ. Spread of amikacin resistance in Acinetobacter baumannii strains isolated in Spain due to an epidemic strain. J Clin Microbiol 1999 37(3) 758-61. 

JH is a 48-year-old woman with a recent diagnosis of breast cancer and is neutropenic after receiving chemotherapy. She is currently febrile and Acinetobacter baumannii is cultured from the blood. Her PMH is significant for chronic renal insufficiency and a history of seizures. Which of the following is considered appropriate therapy for JH ... 

F Meropenem is the best choice. Ertapenem and ampicillin/sul-bactam do not adequately cover Acinetobacter baumannii. Also, with her history of renal insufficiency and seizures, imipenem would not be appropriate because the patient would be at increased risk for seizures. 

Jimenez-Mejias ME, Pichardo-Guerrero C, Marquez-Rivas EJ, et al. Cerebrospinal fluid penettaUon and pharmacokinetic/pharmacodynamic parameters of inttavenously administered coUstin in a case of multidmg-resistant Acinetobacter baumannii meningitis. Eur J CUn Microbiol Infect Dis 2002 21 212-214. 

S. Magnet, P. Courvalin, and T. Lambert, Resistance-nodulation-cell division-type efflux pump involved in aminoglycoside resistance in Acinetobacter baumannii strain BM4454, Antimicrob. Agents Chemother., 45 (2001) 3375-3380. 

In 2013, Neres and coworker reported the synthesis, biochemical, and microbiological evaluation of a series of pyrazolopyridine derivatives as normucleoside inhibitors of BasE, an adenylating enzyme in the sidero-phore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii. The amino-pyrazolopyridine series was produced via direct... 

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