Resistant Staphylococcus aureus

Smaller than bacteria, viruses contain a chemical compound with protein. They must infect a host to survive for long periods. Viruses depend on the host cells to reproduce. Outside of a host cell, a virus exists as a protein coat or capsid that can enclose within a membrane. While outside the cell, a virus remains metabolically inert. A virus can insert genetic material to take over the functions of the host. An infected cell begins to produce more viral protein and genetic material instead of its usual products. 

Some viruses may remain dormant inside host cells for long periods and cause no obvious change in the host cells. When stimulated, a dormant virus enters a phase that results in new viruses bursting and infecting other cells. Viruses cause a number of diseases, including smallpox, colds, chickenpox, influenza, shingles, hepatitis, polio, rabies, and AIDS. Disinfectants destroy viruses very easily. 

Smaller than bacteria, viruses contain a chemical compound with protein. They must infect a host to survive for long periods. Viruses depend on the host cells to reproduce. Outside of a host cell, a 

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Staphylococcus (MRSA) = methicillin-resistant Staphylococcus aureus. 

As recently as 1970, only about 30 naturally occurring organohalogen compounds were known. It was simply assumed that chloroform, halogenated phenols, chlorinated aromatic compounds called PCBs, and other such substances found in the environment were industrial pollutants. Now, only a third of a century later, the situation js quite different. More than 5000 organohalogen compounds have been found to occur naturally, and tens of thousands more surely exist. From a simple compound like chloromethane to an extremely complex one like vancomycin, a remarkably diverse range of organohalogen compounds exists in plants, bacteria, and animals. Many even have valuable physiological activity. Vancomycin, for instance, is a powerful antibiotic produced by the bacterium Amycolatopsis orientalis and used clinically to treat methicillin-resistant Staphylococcus aureus (MRSA). 

MO M23 M23.004 Lysostaphin Use in treatment of endophthalmitis mediated by methicill in-resistant Staphylococcus aureus... 

Oxazolidinones are a new class of synthetic antimicrobial agents, which have activity against many important pathogens, including methicillin-resistant Staphylococcus aureus and others. Oxazolidinones (e.g. linezolid or eperezolid) inhibit bacterial protein synthesis by inhibiting the formation of the 70S initiation complex by binding to the 50S ribosomal subunit close to the interface with the 3OS subunit. 

Problems of recent years involving listeriosis, salmonellosis, giardiasis and Legionnaire s disease have received attention, as have the re-emergence of tuberculosis and the importance of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). 

HAMILTON-MILLER J M T aud SHAH s (1999) Disorganization of cell division of methicillin-resistant Staphylococcus aureus by a component of tea Camellia sinensis) a study by electron microscopy , FEMS Microbiology Letters, 176, 463-9. 

MRSA methiciUin-resistant Staphylococcus aureus MSSA methiciUin-sensitive Staphylococcus aureus... 

Infections acquired from an external source are referred to as exogenous infections. These infections may occur as a result of human-to-human transmission, contact with exogenous bacterial populations in the environment, and animal contact. Resistant pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus spp. 

MRSA, methici 11in-resistant Staphylococcus aureus MRSE, methici llin-resistant Staphylococcus epidermidis. Adapted, with permission. 

Rybak JM, LaPlante KL. Community-associated methicillin-resistant Staphylococcus aureus A review. Pharmacotherapy 2005 25(1) 74-85. 

Methicillin-resistant Staphylococcus aureus (MRSA) is a common hospital-acquired pathogen and is also increasing in the community. MRSA has presented a problem in the past because it required treatment with vancomycin. Community-acquired MRSA presents a major therapeutic challenge. MRSA can cause pneumonia, cellulitis, and other infections. Clinicians should be aware of the rate of hospital and community MRSA in your geographic area. New treatment options are available for MRSA. They include linezolid, tigecycline, and daptomycin. Prospective clinical trials have not demonstrated benefits of these agents over vancomycin.36-37... 

Colonization with resistant gram-positive organisms (e.g., methicillin-resistant Staphylococcus aureus)... 

MRSA Methicillin-resistant Staphylococcus aureus Paco2 Arterial carbon dioxide tension... 

D. B. Rapid discrimination between methicillin-sensitive and methicillin-resistant Staphylococcus aureus by intact cell mass spectrometry J. Med. Microbiol. 2000, 49, 295-300. 

Edwards-Jones, V. Claydon, M. A. Evason, D. J. Walker, J. Fox, A. J. Gordon, D. B. Rapid discrimination between methicillin-sensitive and methicillin-resistant Staphylococcus aureus by intact cell mass spectrometry. J. Med. Microbiol. 2000, 49, 295-300. 

Joint replacement S. aureus, S. epidermidis Cefazolin 1 gx 1 preoperatively, then every 8 hours x 2 more doses Vancomycin reserved for penicillin-allergic patients or where institutional prevalence of methicillin-resistant Staphylococcus aureus warrants use IA... 

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