Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Calibration instrument quality

The simplest calibration procedure for a gas flow-measuring device is to connect it in series with a reference meter and allow the same flow to pass th tough both instruments. This requires a reference instrument of better metrological quality than the calibrated instrument. One fact to consider when applying this method is that the mass flow rate in the system containing both instruments is constant (assuming no leakage), but the volume flow rate is not. The volume flow rate depends on the fluid density and the density depends on the pressure and the temperature. The correct way to calibrate is to compare either the measured mass... [Pg.1168]

Once analytical results have been produced, invariably a certain amount of manipulation is necessary to translate the results into information that can be understood by the customer. The reporting analyst may have to sort and process a large and varied amount of information in order to produce a small number of final answers. Data from standards may be used to produce calibration curves or calibrate instrument response. Results from quality control samples will have been plotted on charts to ensure that the system was working satisfactorily at the time the measurements were made. Sample data will be quantified by comparison with the standards and suitable corrections made. Then, checks may be made to confirm the results by examining the answers to look for any obvious wrong data. It is... [Pg.207]

As discussed above, the greatest source of error in NIR calibration is usually reference laboratory error, sample nonhomogeneity, and nonrepresentative sampling in the learning (training) set or calibration set population. Instrument quality and equation selection account for only a fraction of the variance or error attributable to NIR analytical technique in current routine application. [Pg.390]

Three calibration blank standards should be analyzed to establish a representative blank level, after which the calibration standards are analyzed. After calibration, the quality control standard should be analyzed to verify the calibration. The sample introduction system is flushed with rinse blank, and the blank solution is analyzed to check for carry-over and the blank level. If the blank level is acceptable, the samples can be analyzed. If the blank values are too high, the flushing of the sample introduction system and analysis of the blank solution should be repeated until an acceptable blank level is reached. The calibration blank value, which is the same as the absolute value of the instrument response, must be lower than the method s detection limit. [Pg.407]

Radiation Detection Instrument Calibration and Quality Assurance... [Pg.15]

A second property of data quality is their agreement with standard measures. For example, is a thermometer used in the field calibrated by comparison to a standard thermometer Does it show 0° C in a bath of ice and distilled water, and does it show precisely the local boiling temperature The agreement with standard measures is called accuracy. A good thermometer has an accuracy of 0.2° C, but many commercial thermometers have lower accuracies, as they may be off a calibrated instrument by 1.0° C or more. Accuracy of chemical analytical data is tested by the analyst with solutions that are carefully prepared from chemically pure compounds. [Pg.104]

Of similar significance to the range issue, suitable approaches for calibration transfer must be accepted by regulators for successful implementation of NIR spectroscopy on a large scale within the pharmaceutical industry. Regardless of instrument quality or the utmost discipline and care during method development, calibration transfer will be a reality if a calibration is used over any length of time. [Pg.130]

The instrument was calibrated with four standards (0-2-4-6 (xg/L for Mn) with three measurement replicates each [4], Samples and control standard (4 fxg/L for Mn) were also measured three times. The control standard was analysed for calibration curve quality control (see Quality control ). [Pg.65]

Quantitative results with accuracy and precision comparable with those of the central laboratory Buht-in/integrated calibration and quality control Ambient temperature storage for reagents Results provided as hard copy, stored, and available for transmission Low instrument cost Service by exchange Built-in regulatory record keeping... [Pg.300]

Quality Assurance and Quality Control. The terms "quality assurance"(QA) and "quality control"(QC) need to be defined. They are often used interchangeably, but to the professional they refer to two different activities. Quality control refers to those actions taken in the laboratory in an attempt to keep the measurement system in control. Examples would be running reference standards, calibrating Instruments, keeping quality control charts, etc. Quality assurance refers to the system or program whereby management assures itself (and its clients) that the quality control measures are being applied, and that the results reported do, in fact, refer to the sample that was submitted or collected by the laboratory. [Pg.105]

One of the most important aspects of using a fesf facility to obtain experimental data is having the ability to check and verify fhe accuracy of fhe dafa being collected. In a test facility with properly calibrated instrumentation mass and energy balance closures within a few percentages are frequently achieved. When field data is obtained from commercial fhermal oxidizers fhe quality of the data is often questionable. This is because there is seldom time to obtain steady-state conditions, means to verify fhe accuracy of the instrumentation, or even complete data to close a mass and energy balance around the process to see if the measured data appears to be correct. [Pg.693]

Upon promotion to Phase 4, all quality critical data is reviewed and if required, re-measured with calibrated instruments. This new document is stamped Product Dossier Copy. ... [Pg.714]

Representatives of the organization in the ES H center delegated the responsibility for radiation protection instrumentation are responsible for specifying, maintaining, and calibrating all fixed and portable radiation instruments. They are also responsible for calibration and quality assurance for these instruments in accordance with the RPPM. Periodic operability checks are accomplished by the radiation protection organization. [Pg.253]

Measurement and Calibration Many inspections and testing methods depend on quality instruments. It is essential to inspect and calibrate instruments at regular intervals. [Pg.560]

An appropriate service for calibration and quality assurance should be provided for all monitoring instruments used in the plant and included in the RPR The service should ensure traceability to national standards laboratories. The instruments available should cover measuring ranges that extend from below any applicable reference level up to radiation levels anticipated to prevail under accident conditions. [Pg.19]

In Manufacturing, one major aspect of quality is lack of variability i.e., reproducibility. Quality in production means having reproducible processing equipment and materials comprehensive MPIs and travelers operators trained to follow the instructions and product testing that reveals variability in a short time frame after production. These factors are considered in a quality audit of the manufacturing process. Manufacturability means (or should mean) the ability to make a quality product at a profit. In R D, quality is more subjective but includes the ability of others to reproduce the work - this means reproducible experimental conditions, calibrated instruments and controls, and accurate recording of experimental results. [Pg.545]

Quality control elements required by the instrumental analyzer method include analyzer calibration error ( 2 percent of instrument span allowed) verifying the absence of bias introduced by the sampling system (less than 5 percent of span for zero and upscale cah-bration gases) and verification of zero and calibration drift over the test period (less than 3 percent of span of the period of each rim). [Pg.2200]

In addition to fulfilling the in-house requirements for quality control, state and local air monitoring networks which are collecting data for compliance purposes are required to have an external performance audit on an annual basis. Under this program, an independent organization supplies externally calibrated sources of air pollutant gases to be measured by the instrumentation undergoing audit. An audit report summarizes the performance of the instruments. If necessary, further action must be taken to eliminate any major discrepancies between the internal and external calibration results. [Pg.224]

From the calibration point of view, manometers can be divided into two groups. The first, fluid manometers, are fundamental instruments, where the indication of the measured quantity is based on a simple physical factor the hydrostatic pressure of a fluid column. In principle, such instruments do not require calibration. In practice they do, due to contamination of the manometer itself or the manometer fluid and different modifications from the basic principle, like the tilting of the manometer tube, which cause errors in the measurement result. The stability of high-quality fluid manometers is very good, and they tend to maintain their metrological properties for a long period. [Pg.1151]

Enzyme Reference Serums. Several companies sell lyophilized or stabilized reference serums for the calibration of instruments and for quality control. The label values given for the enzymatic activity of these serums should never be taken at face value, as at times they may be quite erroneous (19,33). Also, these values should only be used for the assay with which they were standardized, as interconversion of activity from one method to another for the same enzyme may often lead to marked errors. For instance, it is not recommended that alkaline phosphatase expressed in Bodansky units be multiplied by a factor to convert it to the units of the Ring-Armstrong method, or any other method for that matter. [Pg.190]

Permeability is another method for obtaining information about pcirticle diameters. If one packs a tube with a weight of powder exactly equal to its density, and applies a calibrated gas pressure through the tube, the pressure drop can be equated to an average particle size. The instrument based on this principle is called the "Fisher Sub-Sieve Sizer ". Only one value can be obtained but the method is fast and reproducible. The instrument itself is not expensive and the method can be applied to quality control problems of powders. Permeametry is usefiil in the particle range of 0.5 to 50 n. [Pg.245]


See other pages where Calibration instrument quality is mentioned: [Pg.204]    [Pg.43]    [Pg.383]    [Pg.121]    [Pg.13]    [Pg.59]    [Pg.383]    [Pg.50]    [Pg.567]    [Pg.260]    [Pg.741]    [Pg.715]    [Pg.707]    [Pg.312]    [Pg.410]    [Pg.494]    [Pg.1125]    [Pg.1159]    [Pg.737]    [Pg.1]    [Pg.295]    [Pg.304]   
See also in sourсe #XX -- [ Pg.32 ]




SEARCH



Calibration quality

Instrumental calibration

Quality instrumentation

© 2024 chempedia.info