Antimicrobial deodorants

Controversy over alteration of the microbial flora of the skin flared in the FDA Over-the-Counter (OTC) Review of Antimicrobial Drugs, especially with reference to total body exposure to antimicrobial/deodorant soaps. The relationship of routine bathing (rinsing) with these soaps with infection was implied in several studies [43-45] and shown conclusively in the study by Taplin [46] in Costa Rica in a population with a high infection rate utilizing a 2% solution of chlorhexidine in water (therefore, 2% available chlorhexidine). 

Uses Antimicrobial, deodorant agent in cosmetics, pharmaceuticals Manuf./Distrib. BDH Sithean Universal Preserv-A-Chem http //www.upichem.com... 

Vopak USA http //www.vopakusa.com-, Westco http //www.westcochemicais.com Ammonium phenolsulfonate CAS 61886-53-1 EINECS/ELINCS 263-293-6 Synonyms Ammonium hydroxybenzenesulfonate Ammonium sulfocarbolate Benzenesulfonic acid, hydroxy-, monoammonium salt Hydroxybenzenesulfonic acid, monoammonium salt Monoammonium hydroxybenzenesulfonate Definition Ammonium sait of phenoisuifonic acid Empihcai C6H6O4S H N Properties M.w. 573.62 Uses Antimicrobial, deodorant agent in cosmetics... 

CAS 369-77-7 EINECS/ELINCS 206-724-5 Synonyms Carbanilide, 4,4 -dichloro-3-(trifluoromethyl)- N-(4-Chlorophenyl)-N -[4-chloro-3-(trifluoromethyl) phenyl] urea 4,4 -Dichloro-3-(trifluoromethyl)-carbanilide Trifluoromethyidichlorocarbanilide 3-(Trifluoromethyl)-4,4 -dichlorocarbanilide 3-Trifluoromethyl-4,4 -dichloro-N,N -diphenylurea Urea, N-(4-chlorophenyl)-N -[4-chloro-3-(trifluoromethyl) phenyl]-Classification Halogenated carbanilide Empin cal C14H9CI2F3N2O Formula CICF3C6H3HNCONHC6H4CI Properties M.w. 349.13 Uses Antimicrobial, deodorant agent in cosmetics Clonitralid... 

Classification Substituted phenol Empirical C8H8CI2O Properties M.w. 191.06 Uses Antimicrobial deodorant agent Manuf/Distrib. ABCR http //www.abcr.de Alfa Aesar http //www.alfa.com Lancaster Synthesis TCI Am. http //www.tciamerica.com Thomas Swan http //www.thomas-swan.co.uk... 

Uses Antimicrobial, deodorant agent in cosmetics medicine (intestinal antiseptic, in dusting powds. for ulcers, slowly granulating wounds, and in dil. sol n. in the eye) ManufJDistrib. Brook-Chem Cambrex Charles City... 

HMIS Health 1, Flammability 1, Reactivity 0 Storage Light-sensitive Uses Antimicrobial, deodorant agent in cosmetics insecticide medicine (antiseptic) astringent in medicines and personal care prods. 

Uses Surfactant, antimicrobial, deodorant, and cleanser in cosmetics Manuf/Distrib. Nanjing Chemlin Somerset Cosmetic Co. 

Oral Cleansing Products. Toothpastes and mouthwashes are considered cosmetic oral cleansers as long as claims about them are restricted to cleaning or deodorization. Because deodorization may depend on reduction of microbiota in the mouth, several antimicrobial agents, either quaternaries, such as benzethonium chloride [121 -54-0] or phenoHcs, such as triclosan [3380-35-5] are permitted. Products that include anticaries or antigingivitis agents or claim to provide such treatment are considered dmgs. 

Deodorant soaps add fragrances that are partially substantive to the skin and that mask body odors, and antimicrobial agents. The antimicrobials, such as Tritfocarban , are deposited on the skin and inhibit bacterial growth and assodated malodors. 

Cosmetics, hair treatment components in hair conditioners, hair rinses, shampoos, deodorants, liquid soaps, antistatic, antimicrobial components... 

One of the most widely used antimicrobial products today is 2,4,4 -trichloro-2 -hydroxydiphenyl ether, known more commonly as triclosan (Fig. 15. Id). Triclosan finds extensive use in mouthwashes, toothpastes, liquid hand soaps, deodorant products, and the like. Although it is effective against most bacteria, it has poor antifungal properties. Triclosan is also important as a textile finish, but since its water solubility is very low, aqueous application requires use of dispersing agents and binders. 

The two main classes of soaps are toilet soap and industrial soap. Toilet soap is usually made from mixtures of tallow and coconut in the ratios 80-90 10-20. The bar soap includes regular and super fatted toilet soaps, deodorant and antimicrobial soaps, floating soaps, and hard water soaps. The super fatted soaps are also made from a mixture of tallow and coconut oil in ratios 50-60 40-50. All soaps practically contain 10 to 30 percent water and also contain perfume that serves to... 

Antimicrobial Agents Antimicrobial agents have been used for a number of years in soap bars as a means of providing additional deodorant protection... 

In cosmetics such as deodorants, benzethonium chloride may be used as an antimicrobial preservative in concentrations up to 0.5% w/v. 

Soaps are used in virtually every household every day. Basic soap is produced by the saponification (hydrolysis with sodium hydroxide) of animal or vegetable fats and has little toxicity. Soaps commonly used, however, contain additives to give them deodorant and antimicrobial properties. Such soaps may contain chloroxylenol, phenol, triclosan, methylisothiazolinone (MIT), and other toxicants that are released into water streams)40 ... 

Thymus vulgaris L. (Thyme) The main component of the essential oil (2.3 %) of partially dried leaves of thyme grown in Kenya was thymol. Thyme oil from other countries is reported to contain thymol (up to 85%) and p-cymene (up to 45%). Thyme is used as a spice due to its apetite stimulating and digestion promotion properties. The oil has strong antimicrobial activity and is also used in the liqueur industiy and as a perfume in soaps, deodorants and hair lotions (34). 

Within the industrial applications of HP, besides the antimicrobial actions they present, they have been used in some countries for soy protein hydrolysis, for freezing, to soften meat, for discoloration of hemoglobin, as by-products in the meat industry, to deodorize proteins, and to make soluble or modify fish proteins (Cheftel, 1995 Palou et al., 2002 Ting and Marshall, 2002a,b). Some examples of the interaction of HP with biological structures of foods are presented in the next section with a major description on milk and its products. 

NB. [Angus] 2-Nitro-l-butanol chemical and pharmaceutical intermediate, in tire cord adhesives, as formaldehyde release agents, deodorant antimicrobials. 

AI3-02258 EINECS 200-957-6 HSDB 5213 2-Methyl-2-nitropropanol 2-Methyl-2-nitropropan-1-ol 2-Methyl-2-nitro-1-propanol 2-Nitro-2-methyl-1-propanol 2-Nitro-2-methylpropanol NMP NMP Cone, NSC 17676 1-Propanol, 2-methyl-2-nltro-, Chemical and pharm-aceutioal intermediate, in tire cord adhesives, as formaldehyde release agents, deodorants, antimicrobials. Chemical intermediate, formaldehyde donor, textile reactant reduces formaldehyde on finished cloth. Solid mp = 89.5° bp ° = 94° Xm = 278 nm (MeOH) slightly soluble in H2O, soluble in organic solvents. Sigma-Aldrich Fine Chem. Whittaker dark Daniels. 

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