Research resources

This work has been supported by the U.S. National Science Foundation (grant MCB-9314854) and the U.S. National Institutes of Health s National Center for Research Resources (grant RR08102 to the UNC/Duke Computational Structural Biology Resource). 

Supported by NSF ASC-9318159, NSF CDA-9422065, NTH Research Resource RR08102, and computer time from the North Carolina Supercomputing Center. An earlier version of this paper was presented at the Eighth SIAM Conference on Parallel Processing for Scientific Computing. 

Clearly, the intended use of a collection item is extremely important to determining the acceptabiHty of a treatment. The degree to which a treatment affects appearance is obviously of the greatest importance for an art object. On the other hand, in natural history collections the collections serve as research resources above all. The effect a preservation or conservation treatment has on these research appHcations is the main consideration. Collections of art, archaeology, history, science, technology, books, archival materials, etc, all have their own values in terms of balance between preservation needs and collections use, and these values are, moreover, constantly subject to reevaluation and change. 

Other offices within ODER may become involved in the review process via consults. Eor example, the Office of Epidemiology and Biostatistics analyzes statistical data, the Office of Research Resources provides bioavailabiHty reviews, and the Office of Compliance determines from the results of inspections whether the firms meet EDA s Current Good Manufacturing Practice (cGMP) regulations. Advisory committees composed of independent experts are often asked to meet and further analyze the data. Often they also advise as to what additional data and information may be needed. After PDA s review is completed, PDA issues either a Summary Basis of Approval (SBA) for the dmg or a recommendation against approval. If approved, PDA releases the SBA and a summary of the safety and effectiveness data to the general pubHc. 

Weifan Zheng, Cheminformatics Research Resources, Division of Medicinal Chemistry, School of Pharmacy, University of North Carolina at Chapel Hill, NC 27599-7360, USA. (weifan zheng unc.edu). 

Part of the work reported herein was performed at SSRL, which is supported by the Department of Energy, Office of Basic Energy Sciences the National Science Foundation, Division of Materials Research and the National Institutes of Health, Biotechnology Resource Program, Division of Research Resources. 

The fourth panel examined research resources within the United States, and the fifth looked at education. 

Gill F Children s Hospital of Philadelphia, Philadelphia, PA To evaluate the effect of lead chelation in conjunction with consumption of multivitamins and minerals on developmental status (humans) National Center for Research Resources... 

Graziano JH Columbia University Health Sciences, New York, NY Precisely determine the bioavailability of Pb in soils representative of the U.S., which contain negligible amounts National Center For Research Resources... 

Hess DL Oregon Reg Primate Research Center, Beaverton, OR Effects of lead on testicular function in rabbits correlating blood levels with physiologically significant effects National Center For Research Resources... 

Howard H Brigham Women s Hospital, Boston, MA Examine the relationship between lead exposure and hypertension, renal dysfunction and cognitive deficits in middle-aged adults National Center for Research Resources... 

Kohler PF Tulane University School of Medicine, New Orleans, LA To determine lead poisoning process to evaluate the use of the oral chelator of lead, Succimer, in the diagnosis and treatment of lead poisoning in adults National Center for Research Resources ... 

Kosnett M University of California, San Francisco, CA Determine the mechanism for lead-associated increases in blood pressure National Center for Research Resources... 

Laughlin NK University of Wisconsin, Madison, Wl Rhesus monkey and determine if the presence of lead stored in bones affects the mobilization of Ca from bone National Center For Research Resources... 

Liebelt E Yale University, New Haven, CT Efficacy of three forms of inpatient chelation that are being utilized in the treatment of children with elevated blood lead levels National Center For Research Resources... 

Rude CS University of Vermont, Burlington, VT Determine the prevalence of lead poisoning among children less than six years of age determine the predictive ability of a prescreening lead questionnaire National Center for Research Resources... 

Schwarz D Joseph Stokes Jr Research Institute Children s Hospital Philadelphia, PA Effects of Chelation With Succimer on Growth and Development of Children with Low Levels of Blood Lead National Center For Research Resources... 

Ongoing studies regarding analytical methods for lead were reported in the Federal Research in Progress File (FEDRIP 1998) database. Only one had relevance to analytical methods and was related to biomarkers. Dr. Liebelt at Yale University, with funding from the National Center for Research Resources, is investigating erythropoietin production in children with lead poisoning. 

Websites http //www.tldiabetes.nih.gov/TlD-RAID http //www2.niddk.nih.gov/Research/Resources/ AllServices.htm Eligibility Academic institutions, non-profit research institutions, biotechnology and pharmaceutical companies, U.S. and non-U.S. entities Intellectual Property It is anticipated that submissions will involve a potential therapeutic that either already has protected IP or will be in the public domain. Specific information can be obtained by contacting T1D-RAID Program officials. 

The National Cancer Institute (NCI) research resources database lists scientific information, tools, reagents, and services for cancer researchers on its website at http //resresources.nci.nih.gov. 

Acknowledgment Partial support for Steven B. Symington is provided by the RI-INBRE Award P20RR016457-10 from the National Center for Research Resources (NCRR), NIH. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NCRR or the NIH. 

The present work of T.T. and T.M. is partially supported by the Japanese Grant-in-Aid for Scienhhc Research Fund of the Ministry of Education, Culture, Sports, Science and Technology (11640272, 13640282), and by the REIMEI Research Resources of Japan Atomic Energy Research Institute (JAERI). 

National Center for Research Resources (NCRR) various information directories available at httpV/www.ncrr.nih.gov/publications.asp... 

This work was supported by the National Center for Research Resources (RR-08119), with additional support from National Institute of Health (NIH) grants GM-35154 and RR-07510-01. 

Acknowledgments We thank Marc Olmsted for his excellent editorial assistance. Much of the research described in this chapter was supported by US Public Health Service grants DA02277 and DA12393 from the National Institute on Drug Abuse, National Institutes of Health, and carried out at the General Clinical Research Center at San Francisco General Hospital Medical Center with support of the Division of Research Resources, National Institutes of Health (RR-00083). 

FIGURE 4.1 Percent identity matrix for tropomyosins from molluscan shellfish, crustacean shellfish, insects and mites, and vertebrate sources. Compiled with the assistance of John C. Wise, Bioinformatics Specialist, University of Nebraska, Food Allergy Research Resource Program. 

The course has many components, such as Chemistry and Society, Development of Industrial Chemistry, and Genealogy, to connect chemistry to history, world events, and real-case problems. Students are required to research resources such as journal articles, society news magazines, books, and patent literature to enhance skills in decision making, inter-... 

The rest of this chapter reviews various types of research resources. It considers online, print, and legal resources. 

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