Nuclear factor kappa B activation

Shimada, T., Waranabe, N., Ohtsuka, Y., Endoh, M., Kojima, K., Hiraishi, H., and Terano, A. (1999). Polaprezinc down-regulates proinflammatory cytokine-induced nuclear factor-kappa B activation and interleukin-8 expression in gastric epithelial cells. J. Pharmacol. Exp. Ther. 291, 345-352. 

HV145 Kanauchi O., A. Andoh, T. Iwanaga, et al. Germinated barley foodstuffs attenuate colonic mucosal damage and mucosal nuclear factor kappa B activity in a spontaneous colitis model. J Gastroenterol Hepatol 1999 14(12) 1173-1179. 

Anethole is known to block the nuclear factor kappa B activation process [359] that is linked with cancer proliferation [272,360]. trans-Anethole was also found to inhibit the in vivo genotoxicity of xenobionts [345]. 

Kim G. M., Xu J., Xu J. M., Song S. K., Yan P., Ku G., Xu X. M., and Hsu C. Y. (2001). Tumor necrosis factor receptor deletion reduces nuclear factor-kappa B activation, cellular inhibitor of apoptosis protein 2 expression, and functional recovery after traumatic spinal cord injury. J. Neurosci. 21 6617-6625. 

Lubin F. D., Johnston L. D., Sweatt J. D., and Anderson A. E. (2005). Kainate mediates nuclear factor-kappa B activation in hippocampus via phosphatidylinositol-3 kinase and extracellular signal-regulated protein kinase. Neuroscience 133 969-981. 

Shen W. H., Zhang C. Y., and Zhang G. Y. (2003). Antioxidants attenuate reperfusion injury after global brain ischemia through inhibiting nuclear factor-kappa B activity in rats. Acta Pharmacol. Sinica 24 1125-1130. 

Ebadi, M., Sharma, S.K., Wanpen, S., and Amorpan, A., Coenzyme Q10 inhibits mitochondrial complex-1 down-regulation and nuclear factor-kappa B activation, J. Cell Mol. Med., 8, 213-222, 2004. 

Aggarwal, B.B., and Shishoda, S., Suppression of the nuclear factor- kappa B activation pathway by spice-derived phytochemicals Reasoning for seasoning, Ann. NY Acad. Sci., 1030,434, 2004. 

Middleton, G., Hamanoue, M., Enokido, Y., Wyatt, S., Pennica, D., Jaffray, E., Hay, R. T., and Davies, A. M. (2000). Cytokine-induced nuclear factor kappa B activation promotes the survival... 

Haridas, V., Darnay, B. G., Natarajan, K., Heller, R., and Aggarwal, B. B. (1998). Overexpression of the p80 TNF receptor leads to TNF-dependent apoptosis, nuclear factor-kappa B activation, and c-Tun kinase activation. J. Immunol. 160, 3152-3162. 

Manna, S. K., Aggaewal, B. B. (1999). Immunosuppressive Leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-kappa B activation and gene expression. 

Bhakar AL, Tannis LL, Zeindler C, Russo MP, Jobin C et al (2002) Constitutive nuclear factor-kappa B activity is required for central neuron survival. J Neurosci 22 8466-8475 Blondeau N, Widmann C, Lazdunski M, Heurteaux C (2001) Activation of the nuclear factor-kappaB is a key event in brain tolerance. J Neurosci 21 4668-4677 Boissiere F, Hunot S, Faucheux B, Duyckaerts C, Hauw JJ, Agid Y et al (1997) Nuclear translocation of NF-kappaB in cholinergic neurons of patients with Alzheimer s disease. Neuroreport 8 2849-2852... 

Choi S, Kim JH, Roh EJ, Ko MJ, Jung JE et al (2006) Nuclear factor-kappa B activated by capacita-tive Ca2-l- entry enhances muscarinic receptor-mediated sAPPalpha release in SH-SY5Y cells. J Biol Chem 281 12722-12728... 

Yang, R, Oz, H. S., Barve, S., de Villiers, W. J., McClain, C. J., Varilek, G. W. (2001). The green tea polyphenol (-)-epigallocatechin-3-gallate blocks nuclear factor-kappa B activation by inhibiting 1 kappa B kinase activity in the intestinal epithelial cell line IEC-6. Molecular Pharmacology, 60, 528-533. 

Janssen YMW, Sen CK. 1999. Nuclear factor kappa B activity in response to oxidants and antioxidants. Methods Enzymol 300 363-374. 

Haselbeck KM, Bierrhaus A, Trwin S, Kirchner A, Navroth P, Schatzer U, Neudorfer A, Heuss D (2004) Receptor for advanced glycation endproduct (RAGE)-mediated nuclear factor-[kappa]B activation in vasculitic neuropathy. Muscle Nerve 29 853-860. 

Levine, L., J.A. Lucci, 3rd, B. Pazdrak, J.Z. Cheng, Y.S. Guo, C.M. Townsend, Jr., and M.R. Hellmich. Bombesin stimulates nuclear factor kappa B activation and expression of proangiogenic factors in prostate cancer cells. Cancer Res 63 3495-502, 2003. 

Fliguchi, M., Singh, S., Jaffrezou, J.P., and Aggarwal, B.B., Acidic sphingomyelinase-generated ceramide is needed but not sufficient for TNF-induced apoptosis and nuclear factor-kappa B activation, J Immunol, 157 (1996) 297-304. 

Kim, I., Moon, S.O., Kim, S.H., Kim, H.J., Koh, Y.S., and Koh, G.Y., Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cellS, J Biol Chem, 276 (2001) 7614-7620. 

D.J. Granville, C.M. Carthy, H. Jiang, J.G. Levy, B.M. McManus, J.Y. Matroule, J. Piette, D.W. Hunt (2000). Nuclear factor-kappa B activation by the photochemothera-peutic agent verteporfin. Blood, 95, 256-262. 

Kang, J.L., Pack, I.S., Hong, S.M., Lee, H.S., and Castranova, V., Silica induces nuclear factor-kappa B activation through tyrosine phosphorylation of I kappa B-alpha in RAW264.7 macrophages, Toxicol Appl. Pharmacol, 169, 59-65, 2000. 

Desaki, M., Takizawa, H., Kasama, T., Kobayashi, K., Morita, Y., and Yamamoto, K., Nuclear factor-kappa b activation in silica-induced interleukin 8 production by human bronchial epithelial cells. Cytokine, 12, 1257-1260, 2000. 

Chen, F., Lu, Y., Kuhn, D.C., Maki, M., Shi, X., Sun, S.C., and Demers, L.M., Calpain contributes to silica-induced I kappa B-alpha degradation and nuclear factor-kappa B activation, Arch. Biochem. Biophys., 342, 383-388, 1997. 

Peng, Q., Wei, Z., and Lau, B.H., Pycnogenol inhibits tumor necrosis factor-alpha-induced nuclear factor kappa B activation and adhesion molecule expression in human vascular endothelial cells. Cell Molecular Life Scl, 57, 834-841, 2000. 

Kim JI, Ju WK, Choi JH, Choi E, Carp RI, Wisniewski HM, Kim YS (1999) Expression of cytokine genes and increased nuclear factor-kappa B activity in the brains of scrapie-infected mice. Brain... 

TNK = TANK-binding kinase TANK = TRAF-family member-associated NFkB activator TRAP- (tumor necrosis factor receptor-associated factor-) associated nuclear factor kappa B activator STEAP, six transmembrane epithelial antigen, prostate. 

Sadikot RT, Jansen ED, Blackwell TR, Zoia O, Yuli F, Christman JW, Blackwell TS. High-dose dexamethasone accentuates nuclear factor-kappa B activation in endotoxin-treated mice. Am J Resp Crit Care Med 2001 164(5) 873-878. 

Blackwell TS, Yuli EE, Chen CL, Venkatakrishnan A, Blackwell TR, Hicks DJ, Lancaster LH, Christman JW, Kerr LD. Multiorgan nuclear factor kappa B activation in a transgenic mouse model of systemic inflammation. Am J Respir Crit Care Med 2000 162(3) 1095-1101. 

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