Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

4- Monoamine oxidase inhibitors

The high incidence of drug-food and drug-drug interactions rules out monoamine oxidase inhibitors as antidepressants of first choice. However, there are circumstances in which these agents may be used effectively and successfully  [Pg.424]

The newer agents that may have actions that are novel or atypical include maprotiline, amoxapine, fluoxetine, trazodone, bupropion, mianserin, and alprazolam. [Pg.424]


Patients receiving monoamine oxidase inhibitors (MAOI) as antidepressant therapy have been especially subject to the hypertensive effects of vasoactive amines (52). These dietary amines have also been impHcated as causative agents ia migraine. Other aaturaHy occurring alkaloids (qv) have been recognized for centuries as possessing neurological stimulant and depressant properties. [Pg.478]

Monoamine—Oxidase Inhibitors. In the mid-1950s, tuberculosis patients with depression being treated with iproniazid (42) were occasionally reported to become euphoric. This observation led to the discovery of irreversible monoamine—oxidase (MAO) inhibiting properties. Hydrazine and nonhydrazine-related MAO inhibitors were subsequentiy shown to be antidepressants (122). Three other clinically effective irreversible MAO inhibitors have been approved for treatment of major depression phenelzine (43), isocarboxazid (44), and tranylcypromine (45). [Pg.230]

Monoamine Oxidase Inhibitors. MAOIs inactivate the enzyme MAO, which is responsible for the oxidative deamination of a variety of endogenous and exogenous substances. Among the endogenous substances are the neurotransmitters, norepinephrine, dopamine, and serotonin. The prototype MAOI is iproniazid [54-92-2] (25), originally tested as an antitubercular dmg and a close chemical relative of the effective antitubercular, isoniazid [54-85-3] (26). Tubercular patients exhibited mood elevation, although no reHef of their tuberculosis, following chronic administration of iproniazid. In... [Pg.465]

Normally, dietary tyramine is broken down in the gastrointestinal tract by MAO and is not absorbed. In the presence of MAOI, however, all of its potent sympathomimetic actions are seen. Other side effects of MAOI include excessive CNS stimulation, orthostatic hypotension, weight gain, and in rare cases hepatotoxicity. Because the monoamine oxidase inhibitors exhibit greater toxicity, yet no greater therapeutic response than other, newer agents, clinical use has been markedly curtailed. The primary use for MAOIs is in the treatment of atypical depressions, eg, those associated with increased appetite, phobic anxiety, hypersomnolence, and fatigues, but not melancholia (2). [Pg.466]

Pharmacologically useful isoxazoles (B-82MI41600) include antibacterial sulfonamides (614), (615) and (616), semisynthetic penicillins (617), (618), (619) and (620), semisynthetic cephalosporin (621), anabolic steroid (622), the monoamine oxidase inhibitor (623) (used in psychotherapy), antiinflammatory agent (624) and antitumor agent (625). [Pg.127]

Pargyline hydrochloride (Eutonyl, (V-methyl-n-propargylbenzylamine hydrochloride) [306-07-0] M 195.7, m 154-155 , 155 , pK 6.9. Recrystd from EtOH-Et20 and dried in vacuo. It is very soluble in H2O, in which it is unstable. The free base has b 101-103°/ 1mm. It is a glucuronyl transferase inducer and a monoamine oxidase inhibitor, [von Braun et al. Justus Liebigs Ann Chem 445 205 1928, Yeh and Mitchell Experientia 28 298 1972 Langslrom et al. Science 225 1480 1984.]... [Pg.556]

MAO (monoamine oxidase) inhibitor. An agent that blocks one of the enzymes that deaminates amines. [Pg.453]

Therapeutic Function Antidepressant monoamine oxidase inhibitor Chemical Name 4-Pyridinecarboxylic acid 2-(1-methylethyl)hydrazide Common Name —... [Pg.837]

Monoamine oxidases Inhibitors Depressive illness Parkinson s disease Neuroprotection neurorescue... [Pg.783]

Monoamine Oxidases and their Inhibitors. Table 4 Nonselective and selective monoamine oxidase inhibitors... [Pg.786]

Youdim MB, Edmondson D, Tipton KF (2006) The therapeutic potential of monoamine oxidase inhibitors. Nat Rev Neurosci 7(4) 295-309... [Pg.791]

The term pasaon flower is used to denote many of the approximately 400 species of the herb. F saon flower has been used in medicine to treat pain, anxiety, and insomnia. Some herbalists use the herb to treat symptoms of parkinsonism. F saon flower is often used in combination with other herbs , such a valerian, chamomile, and hops, for promoting relaxation, rest and sleep. Although no adverse reactions have been reported, large doses may cause CNS depression. The use of passion flower is contraindicated in pregnancy and in patientstaking the monoamine oxidase inhibitors (MAOIs). Fission flower contains coumarin, and the risk of bleeding may be increased when used in patientstaking warfarin and pasaon flower. [Pg.172]

The skeletal muscle relaxants are contraindicated in patients with known hypersensitivity. Baclofen is contraindicated in skeletal muscle spasms caused by rheumatic disorders. Carisoprodol is contraindicated in patients with a known hypersensitivity to meprobamate. Cyclobenzaprine is contraindicated in patients with a recent myocardial infarction, cardiac conduction disorders, and hyperthyroidism, hi addition, cyclobenzaprine is contraindicated within 14 days of the administration of a monoamine oxidase inhibitor. Oral dantrolene is contraindicated in patients with active hepatic disease and muscle spasm caused by rheumatic disorders and during lactation. See Chapter 30 for information on diazepam. [Pg.191]

The amphetamines and the anorexiants should not be given during or within 14 days after administration of monoamine oxidase inhibitors (see Chap. 31) because the patient may experience hypertensive crisis and intracranial hemorrhage. When guanethidine is administered with the amphetamines or the anorexiants, the antihypertensive effect of guanethidine may decrease. Coadministration of the amphetamines or the anorexiants with the tricyclic antidepressants may decrease the effects of the amphetamines or the anorexiants. [Pg.249]

The dopaminergic drug are contraindicated in patients with known hypersensitivity to the drugs. Levodopa is contraindicated in patients with narrow-angle glaucoma, those receiving a monoamine oxidase inhibitor (see... [Pg.267]

Levodopa interacts with many different drugs. When levodopa is used with phenytoin, reserpine, and papaverine, there is a decrease in response to levodopa The risk of a hypertensive crisis increases when levodopa is used with the monoamine oxidase inhibitors (see Chap. 31). Foods high in pyridoxine (vitamin B6) or vitamin B6 preparations reverse the effect of levodopa However, when carbidopa is used with levodopa, pyridoxine has no effect on the action of levodopa hi fact, when levodopa and carbidopa are given together, pyridoxine may be prescribed to decrease the adverse effects associated with levodopa... [Pg.267]

The decongestants are contraindicated in patients with known hypersensitivity, hypertension, and severe coronary artery disease These drugs are also contraindicated in patients taking monoamine oxidase inhibitors (MAOIs). Naphazoline is contraindicated in patients with glaucoma. [Pg.329]

When dextromethorphan is administered with the monoamine oxidase inhibitors (see Chap. 31), patients may experience hypotension, fever, nausea, jerking motions to the leg, and coma... [Pg.352]

The hypotensive effects of most antihypertensive dru are increased when administered with diuretics and other antihypertensives. Many dnigp can interact with the antihypertensive drugs and decrease their effectiveness (eg, antidepressants, monoamine oxidase inhibitors, antihistamines, and sympathomimetic bronchodilators). When the ACE inhibitors are administered with the NSAIDs, their antihypertensive effect may be decreased. Absorption of the ACE inhibitors may be decreased when administered with the antacids. Administration of potassium-sparing diuretics or potassium supplements concurrently with the ACE inhibitors may cause hyperkalemia. When the angiotensin II receptor agonists are administered with... [Pg.402]

The antidiarrheal drugs cause an additive CNS depression when administered with alcohol, antihistamines, narcotics, and sedatives or hypnotics. There are additive cholinergic effects when administered with other drugp having anticholinergic activity, such as antidepressants or antihistamines. Concurrent use of the antidiarrheals witii a monoamine oxidase inhibitor increases the risk of a hypertensive crisis. [Pg.473]

Ephedra (sea grape, ma-huang, yellow horse) ephedra sinica Relieves colds, improves respiratory function, headaches, diuretic effects 3heart rate, psychosis l hedra should only be used after consulting with the physician. Many restrictions apply and the herb can cause serious reactions. Do not use with cardiac glycosides, monoamine oxidase inhibitor halothane, guanethidine, (MAOIs) or oxytocin. Do not use with 3. John s wort or in weight loss formulas. [Pg.660]

Serious adverse effects of epinephrine potentially occur when it is given in an excessive dose, or too rapidly, for example, as an intravenous bolus or a rapid intravenous infusion. These include ventricular dysrhythmias, angina, myocardial infarction, pulmonary edema, sudden sharp increase in blood pressure, and cerebral hemorrhage. The risk of epinephrine adverse effects is also potentially increased in patients with hypertension or ischemic heart disease, and in those using (3-blockers (due to unopposed epinephrine action on vascular Ui-adrenergic receptors), monoamine oxidase inhibitors, tricyclic antidepressants, or cocaine. Even in these patients, there is no absolute contraindication for the use of epinephrine in the treatment of anaphylaxis [1,5,6]. [Pg.213]


See other pages where 4- Monoamine oxidase inhibitors is mentioned: [Pg.645]    [Pg.218]    [Pg.228]    [Pg.465]    [Pg.465]    [Pg.469]    [Pg.675]    [Pg.676]    [Pg.704]    [Pg.709]    [Pg.574]    [Pg.574]    [Pg.78]    [Pg.1045]    [Pg.171]    [Pg.205]    [Pg.215]    [Pg.281]    [Pg.284]    [Pg.306]    [Pg.337]    [Pg.491]    [Pg.504]    [Pg.627]    [Pg.403]    [Pg.198]    [Pg.276]   
See also in sourсe #XX -- [ Pg.1017 ]

See also in sourсe #XX -- [ Pg.149 , Pg.232 , Pg.254 ]

See also in sourсe #XX -- [ Pg.42 , Pg.44 ]

See also in sourсe #XX -- [ Pg.252 , Pg.339 , Pg.341 ]

See also in sourсe #XX -- [ Pg.221 ]

See also in sourсe #XX -- [ Pg.28 , Pg.47 , Pg.50 , Pg.132 , Pg.141 , Pg.157 , Pg.164 , Pg.244 ]

See also in sourсe #XX -- [ Pg.59 , Pg.321 ]

See also in sourсe #XX -- [ Pg.253 , Pg.292 ]

See also in sourсe #XX -- [ Pg.423 ]

See also in sourсe #XX -- [ Pg.295 , Pg.296 , Pg.297 , Pg.298 , Pg.299 ]

See also in sourсe #XX -- [ Pg.12 ]

See also in sourсe #XX -- [ Pg.126 ]

See also in sourсe #XX -- [ Pg.181 ]

See also in sourсe #XX -- [ Pg.2 , Pg.22 , Pg.221 , Pg.223 ]

See also in sourсe #XX -- [ Pg.1017 ]

See also in sourсe #XX -- [ Pg.212 , Pg.222 ]

See also in sourсe #XX -- [ Pg.623 ]

See also in sourсe #XX -- [ Pg.21 , Pg.137 ]

See also in sourсe #XX -- [ Pg.23 , Pg.28 , Pg.31 , Pg.32 ]

See also in sourсe #XX -- [ Pg.366 , Pg.366 , Pg.367 ]

See also in sourсe #XX -- [ Pg.3 ]

See also in sourсe #XX -- [ Pg.2 , Pg.178 , Pg.351 ]

See also in sourсe #XX -- [ Pg.198 ]

See also in sourсe #XX -- [ Pg.1538 ]

See also in sourсe #XX -- [ Pg.323 , Pg.388 ]

See also in sourсe #XX -- [ Pg.119 , Pg.125 ]

See also in sourсe #XX -- [ Pg.161 , Pg.183 ]

See also in sourсe #XX -- [ Pg.92 , Pg.228 ]

See also in sourсe #XX -- [ Pg.21 , Pg.137 ]

See also in sourсe #XX -- [ Pg.126 ]

See also in sourсe #XX -- [ Pg.41 , Pg.43 , Pg.96 , Pg.195 , Pg.286 ]

See also in sourсe #XX -- [ Pg.2 , Pg.22 , Pg.221 , Pg.223 ]

See also in sourсe #XX -- [ Pg.1017 ]

See also in sourсe #XX -- [ Pg.718 ]

See also in sourсe #XX -- [ Pg.357 ]

See also in sourсe #XX -- [ Pg.40 , Pg.47 , Pg.48 ]

See also in sourсe #XX -- [ Pg.145 ]

See also in sourсe #XX -- [ Pg.541 ]

See also in sourсe #XX -- [ Pg.226 ]

See also in sourсe #XX -- [ Pg.319 ]

See also in sourсe #XX -- [ Pg.68 ]

See also in sourсe #XX -- [ Pg.207 ]

See also in sourсe #XX -- [ Pg.6 , Pg.485 , Pg.486 , Pg.718 ]

See also in sourсe #XX -- [ Pg.2 , Pg.28 ]

See also in sourсe #XX -- [ Pg.27 , Pg.133 , Pg.143 ]

See also in sourсe #XX -- [ Pg.44 , Pg.542 ]

See also in sourсe #XX -- [ Pg.21 , Pg.137 ]

See also in sourсe #XX -- [ Pg.83 , Pg.117 ]

See also in sourсe #XX -- [ Pg.82 , Pg.85 , Pg.86 ]

See also in sourсe #XX -- [ Pg.197 , Pg.200 ]

See also in sourсe #XX -- [ Pg.402 , Pg.467 , Pg.468 , Pg.598 ]

See also in sourсe #XX -- [ Pg.45 , Pg.46 ]

See also in sourсe #XX -- [ Pg.161 ]

See also in sourсe #XX -- [ Pg.19 , Pg.317 ]

See also in sourсe #XX -- [ Pg.270 , Pg.274 ]

See also in sourсe #XX -- [ Pg.301 , Pg.418 ]

See also in sourсe #XX -- [ Pg.298 , Pg.300 , Pg.301 ]

See also in sourсe #XX -- [ Pg.295 , Pg.306 , Pg.319 , Pg.323 ]

See also in sourсe #XX -- [ Pg.269 , Pg.270 , Pg.270 ]

See also in sourсe #XX -- [ Pg.44 , Pg.542 ]

See also in sourсe #XX -- [ Pg.244 , Pg.359 ]

See also in sourсe #XX -- [ Pg.113 ]

See also in sourсe #XX -- [ Pg.6 ]

See also in sourсe #XX -- [ Pg.436 , Pg.437 ]

See also in sourсe #XX -- [ Pg.514 ]

See also in sourсe #XX -- [ Pg.6 , Pg.8 , Pg.12 , Pg.13 , Pg.17 , Pg.361 ]

See also in sourсe #XX -- [ Pg.109 ]

See also in sourсe #XX -- [ Pg.357 ]

See also in sourсe #XX -- [ Pg.160 ]

See also in sourсe #XX -- [ Pg.365 , Pg.365 ]




SEARCH



Aggression monoamine oxidase inhibitor

Amfetamine Monoamine oxidase inhibitors

Amitriptyline Monoamine oxidase inhibitors

Amphetamines monoamine oxidase inhibitors

Anticonvulsants monoamine oxidase inhibitors

Antidepressant agents monoamine oxidase inhibitors

Antidepressant drugs monoamine oxidase inhibitors

Antidepressants Monoamine oxidase inhibitors Serotonin-selective

Antidepressants monoamine oxidase inhibitors

Antihypertensives Monoamine oxidase inhibitors

Atomoxetine Monoamine oxidase inhibitors

Barbiturates Monoamine oxidase inhibitors

Bupropion Monoamine oxidase inhibitors

Buspirone monoamine oxidase inhibitors

Caffeine Monoamine oxidase inhibitors

Cheese, monoamine oxidase inhibitors

Chlorpromazine monoamine oxidase inhibitors

Citalopram Monoamine oxidase inhibitors

Cocaine monoamine oxidase inhibitors

Depression monoamine oxidase inhibitors

Depressive disorders monoamine oxidase inhibitors

Disulfiram Monoamine oxidase inhibitors

Dopamine Monoamine oxidase inhibitors

Fenfluramine monoamine oxidase inhibitors

Fluoxetine monoamine oxidase inhibitors

Fluvoxamine Monoamine oxidase inhibitors

Hormonal) Monoamine oxidase inhibitors

Hypericum monoamine oxidase inhibitors

Imipramine Monoamine oxidase inhibitors

Inhibitors of monoamine oxidases

Instructions for patients taking nonselective monoamine oxidase inhibitors

Isoniazid monoamine oxidase inhibitors

Linezolid Monoamine oxidase inhibitors

Lithium monoamine oxidase inhibitors

Liver , monoamine oxidase inhibitor interaction

Look up the names of both individual drugs and their drug groups to access full information Monoamine oxidase inhibitors

Medicines) Monoamine oxidase inhibitors

Methadone Monoamine oxidase inhibitors

Methyldopa Monoamine oxidase inhibitors

Methylphenidate Monoamine oxidase inhibitors

Mirtazapine Monoamine oxidase inhibitors

Monoamine Oxidases and their Inhibitors

Monoamine inhibitors

Monoamine oxidase

Monoamine oxidase A inhibitor

Monoamine oxidase MAO) inhibitors

Monoamine oxidase inhibitor MAOI)

Monoamine oxidase inhibitor contraindications

Monoamine oxidase inhibitor interaction and

Monoamine oxidase inhibitors MAOIs) interactions

Monoamine oxidase inhibitors MAOls)

Monoamine oxidase inhibitors Parkinson disease

Monoamine oxidase inhibitors Parkinsonism

Monoamine oxidase inhibitors SSRIs

Monoamine oxidase inhibitors action

Monoamine oxidase inhibitors administration

Monoamine oxidase inhibitors adverse effects

Monoamine oxidase inhibitors alcohol

Monoamine oxidase inhibitors anxiety disorders

Monoamine oxidase inhibitors anxiolytics

Monoamine oxidase inhibitors applications

Monoamine oxidase inhibitors available drugs

Monoamine oxidase inhibitors cardiovascular

Monoamine oxidase inhibitors cheese effect

Monoamine oxidase inhibitors chemical structures

Monoamine oxidase inhibitors classification

Monoamine oxidase inhibitors consequences

Monoamine oxidase inhibitors development

Monoamine oxidase inhibitors dextromethorphan

Monoamine oxidase inhibitors dietary interactions with

Monoamine oxidase inhibitors discontinuation

Monoamine oxidase inhibitors discovery

Monoamine oxidase inhibitors distribution

Monoamine oxidase inhibitors dosage

Monoamine oxidase inhibitors dosing

Monoamine oxidase inhibitors drug administration

Monoamine oxidase inhibitors drug interactions

Monoamine oxidase inhibitors drug interactions with

Monoamine oxidase inhibitors drug overdose

Monoamine oxidase inhibitors drug withdrawal

Monoamine oxidase inhibitors during pregnancy

Monoamine oxidase inhibitors efficacy

Monoamine oxidase inhibitors ephedrine

Monoamine oxidase inhibitors examples

Monoamine oxidase inhibitors fluoxetine with

Monoamine oxidase inhibitors food interactions

Monoamine oxidase inhibitors food-drug interactions

Monoamine oxidase inhibitors foods

Monoamine oxidase inhibitors gastrointestinal effects

Monoamine oxidase inhibitors ginseng

Monoamine oxidase inhibitors glaucoma with

Monoamine oxidase inhibitors history

Monoamine oxidase inhibitors in Parkinson’s disease

Monoamine oxidase inhibitors in depression

Monoamine oxidase inhibitors in posttraumatic stress disorder

Monoamine oxidase inhibitors in social anxiety disorder

Monoamine oxidase inhibitors indications

Monoamine oxidase inhibitors interaction with foods

Monoamine oxidase inhibitors interaction with other drugs

Monoamine oxidase inhibitors interactions

Monoamine oxidase inhibitors lactation

Monoamine oxidase inhibitors levodopa

Monoamine oxidase inhibitors limitations

Monoamine oxidase inhibitors liver

Monoamine oxidase inhibitors long-term effects

Monoamine oxidase inhibitors mechanism

Monoamine oxidase inhibitors mechanism of action

Monoamine oxidase inhibitors monitoring

Monoamine oxidase inhibitors nefazodone

Monoamine oxidase inhibitors nervous system

Monoamine oxidase inhibitors neuroleptic drugs

Monoamine oxidase inhibitors nonselective

Monoamine oxidase inhibitors opioid analgesics

Monoamine oxidase inhibitors overdose

Monoamine oxidase inhibitors patient information

Monoamine oxidase inhibitors pharmacological properties

Monoamine oxidase inhibitors phenylephrine

Monoamine oxidase inhibitors pregnancy

Monoamine oxidase inhibitors restrictions

Monoamine oxidase inhibitors selective

Monoamine oxidase inhibitors selective irreversible

Monoamine oxidase inhibitors side effects

Monoamine oxidase inhibitors social anxiety

Monoamine oxidase inhibitors structure

Monoamine oxidase inhibitors structure-activity relationship

Monoamine oxidase inhibitors sumatriptan

Monoamine oxidase inhibitors therapeutic efficacy

Monoamine oxidase inhibitors trazodone

Monoamine oxidase inhibitors tricyclic antidepressants

Monoamine oxidase inhibitors tricyclic antidepressants with

Monoamine oxidase inhibitors uses

Monoamine oxidase inhibitors values

Monoamine oxidase inhibitors venlafaxine

Monoamine oxidase inhibitors with methylphenidate

Monoamine oxidase inhibitors, role

Monoamine oxidase irreversible inhibitors

Monoamine oxidase type B inhibitors

Monoamine-oxidase B inhibitors

Morphine Monoamine oxidase inhibitors

Older Antidepressants Tricyclics and Monoamine Oxidase Inhibitors

Opioids monoamine oxidase inhibitors

Oxidase inhibitors

Oxidases monoamine oxidase

Panic disorder monoamine oxidase inhibitors

Paroxetine Monoamine oxidase inhibitors

Pharmacokinetics monoamine oxidase inhibitors

Phenothiazines Monoamine oxidase inhibitors

Postural hypotension, with monoamine oxidase inhibitors

Procarbazine monoamine oxidase inhibitors

Prozac Interaction With Monoamine Oxidase Inhibitors and Tryptophan

Pseudoephedrine Monoamine oxidase inhibitors

Psychotropic agents monoamine oxidase inhibitors

RIMAs (Reversible inhibitors of monoamine oxidase

Rasagiline Monoamine oxidase inhibitors

Reserpine Monoamine oxidase inhibitors

Reversible inhibitor of monoamine oxidase A

Reversible inhibitor of monoamine oxidase type A

Reversible inhibitors of monoamine oxidase

Reversible inhibitors of monoamine oxidase type

Reversible monoamine oxidase inhibitors

Reversible monoamine oxidase inhibitors RIMA) type

Selective serotonin reuptake inhibitors monoamine oxidase

Selegiline Monoamine oxidase inhibitors

Sertraline Monoamine oxidase inhibitors

Social anxiety disorder monoamine oxidase inhibitors

Tramadol Monoamine oxidase inhibitors

Tricyclic antidepressants and monoamine oxidase inhibitors

Triptans Monoamine oxidase inhibitors

Tyramine, dietary, monoamine oxidase inhibitor

Tyramine, monoamine oxidase inhibitors

© 2024 chempedia.info