Monoamine oxidase inhibitors contraindications

The term pasaon flower is used to denote many of the approximately 400 species of the herb. F saon flower has been used in medicine to treat pain, anxiety, and insomnia. Some herbalists use the herb to treat symptoms of parkinsonism. F saon flower is often used in combination with other herbs , such a valerian, chamomile, and hops, for promoting relaxation, rest and sleep. Although no adverse reactions have been reported, large doses may cause CNS depression. The use of passion flower is contraindicated in pregnancy and in patientstaking the monoamine oxidase inhibitors (MAOIs). Fission flower contains coumarin, and the risk of bleeding may be increased when used in patientstaking warfarin and pasaon flower. 

The skeletal muscle relaxants are contraindicated in patients with known hypersensitivity. Baclofen is contraindicated in skeletal muscle spasms caused by rheumatic disorders. Carisoprodol is contraindicated in patients with a known hypersensitivity to meprobamate. Cyclobenzaprine is contraindicated in patients with a recent myocardial infarction, cardiac conduction disorders, and hyperthyroidism, hi addition, cyclobenzaprine is contraindicated within 14 days of the administration of a monoamine oxidase inhibitor. Oral dantrolene is contraindicated in patients with active hepatic disease and muscle spasm caused by rheumatic disorders and during lactation. See Chapter 30 for information on diazepam. 

The dopaminergic drug are contraindicated in patients with known hypersensitivity to the drugs. Levodopa is contraindicated in patients with narrow-angle glaucoma, those receiving a monoamine oxidase inhibitor (see... 

The decongestants are contraindicated in patients with known hypersensitivity, hypertension, and severe coronary artery disease These drugs are also contraindicated in patients taking monoamine oxidase inhibitors (MAOIs). Naphazoline is contraindicated in patients with glaucoma. 

Serious adverse effects of epinephrine potentially occur when it is given in an excessive dose, or too rapidly, for example, as an intravenous bolus or a rapid intravenous infusion. These include ventricular dysrhythmias, angina, myocardial infarction, pulmonary edema, sudden sharp increase in blood pressure, and cerebral hemorrhage. The risk of epinephrine adverse effects is also potentially increased in patients with hypertension or ischemic heart disease, and in those using (3-blockers (due to unopposed epinephrine action on vascular Ui-adrenergic receptors), monoamine oxidase inhibitors, tricyclic antidepressants, or cocaine. Even in these patients, there is no absolute contraindication for the use of epinephrine in the treatment of anaphylaxis [1,5,6]. 

Blockers are contraindicated in patients with decompensated heart failure unless it is caused solely by tachycardia (high output). Other contraindications include sinus bradycardia, concomitant therapy with monoamine oxidase inhibitors or tricyclic antidepressants, and patients with spontaneous hypoglycemia. Side effects include nausea, vomiting, anxiety, insomnia, lightheadedness, bradycardia, and hematologic disturbances. 

Bupropion sustained release (SR) is an effective smoking-cessation treatment. It is contraindicated in patients with a seizure disorder, a current or prior diagnosis of bulimia or anorexia nervosa, and use of a monoamine oxidase inhibitor within the previous 14 days. It can be used in combination with NRT. 

Phenylephrine is a nasal decongestant that mimics the sympathetic system, thereby increasing the heart rate and blood pressure. It may aggravate conditions such as diabetes, hypertension and glaucoma. Patients with hypertension, ischaemic heart disease, hyperthyroidism, diabetes and glaucoma are therefore given topical nasal sympathomimetics rather than systemic sympathomimetics. Both topical and systemic sympathomimetics are contraindicated in patients taking monoamine oxidase inhibitors, because concurrent administration of the two products may lead to a hypertensive crisis. 

Prior sensitivity to any tricyclic drug. Not recommended for use during the acute recovery phase following myocardial infarction. Concomitant use of monoamine oxidase inhibitors (MAOIs) is generally contraindicated. 

Contraindications Coadministration with monoamine oxidase inhibitors (MAOls), hypersensitivity to dextromethorphan or its components... 

Contraindications for Monoamine Oxidase Inhibitors. Physical conditions that may preclude the use of MAOIs include the following ... 

Monoamine oxidase inhibitors Relative contraindication to all opioid analgesics because of the high incidence of hyperpyrexic coma hypertension has also been reported. 

Q8 A pregnancy test is necessary because hypertension is a feature of preeclampsia, a serious condition which can occur in pregnancy and which threatens the life of both mother and foetus. Also, many antihypertensive drugs are contraindicated in pregnancy. It is necessary to know whether the patient is taking prescribed medicines or is self-medicating, as some drugs, such as monoamine oxidase inhibitors (MAOIs), can interact with dietary components to cause a very rapid rise in BP. 

Apraclonidine is contraindicated in patients sensitive to clonidine and those taking monoamine oxidase inhibitors. Caution should be exercised in patients with severe cardiovascular disease, including hypertension. The possibility of vasovagal episodes exists during laser surgery, particularly in patients with a history of such events. 

Brimonidine is contraindicated in patients receiving monoamine oxidase inhibitors. It is not contraindicated... 

Carbamazepine is contraindicated in patients taking monoamine oxidase inhibitors (101,102). The combination can cause sudden high body temperature, extremely high blood pressure, and severe convulsions at least 14 days should be allowed between stopping treatment with one medicine and starting the other. 

Concurrent use of monoamine oxidase inhibitors, which lower the seizure threshold, is a contraindication to etamivan. 

They can be used by patients for whom systemic decongestants are contraindicated, but should be avoided by patients taking monoamine oxidase inhibitors. 

The triptans are contraindicated in patients who have a history of ischemic or vasospastic CAD, cerebrovascular or peripheral vascular disease, or other significant cardiovascular diseases. Because triptans may cause an acute, usually small, increase in blood pressure (BP), they also are contraindicated in patients with uncontrolled hypertension. Naratriptan is contraindicated in patients with severe renal or hepatic impairment. Rizatriptan should be used with caution in patients with renal or hepatic disease but is not contraindicated in such patients. Sumatriptan, rizatriptan, and zolmitriptan are contraindicated in patients who are taking monoamine oxidase inhibitors. 

Trimipramine is contraindicated in patients with known hypersensitivity to tricyclic antidepressants, trazodone, and related compounds in the acute recovery phase of myocardial infarction (MI), because the drug depresses cardiac function and causes dysrhythmia in patients in coma or severe respiratory depression (additive CNS and respiratory depression) and during or within 14 days of therapy with monoamine oxidase inhibitors. 

No dosage adjustment is required in patients with mild to moderate renal impairment however, escitalopram should be used with caution in patients with severe renal impairment. Escitalopram is contraindicated in combination with irreversible monoamine oxidase inhibitors (MAOis), and a period of at least 2 weeks should be allowed between discontinuation of escitaiopram and commencement of an irreversible MAOi and vice versa. Escitaiopram appears to be a well-tolerated and effective antidepressant. 

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