Older Antidepressants Tricyclics and Monoamine Oxidase Inhibitors

There is no perfect solution to depression, nor should there be. And odd as this may sound. .. we should be glad of that. It keeps us human. 

Tricyclic antidepressants (TCAs) cause more overdose deaths than any other drug. That said, TCAs are among the most effective antidepressants. Some studies would assert that this family of antidepressants is more effective than the celebrated SSRIs (of which Prozac is a member). When Prozac was first tested for clinical use, it performed marginally better than placebos. During that same trial, in order to compare the performance of Prozac against a more classic antidepressant, a TCA (imipramine) was also administered to 

Class Drug name Usual Adult Daily dosage I I 8 a 0 s 1 Orthostatic hypotension c 0 1 11 II 5 a 04 il Q - .S 

TCA Amitriptyline (Elavil) 100-300mg/d very hieth very high very high high very low none 

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Contents Introduction, history and brain basics—Older antidepressants tricyclics and monoamine oxidase inhibitors—Selective serotonin reuptake inhibitors—Second generation antidepressants—Lithium, a medication for bipolar depression—Natural depressants—Teens and antidepressants trends and attitudes—Case study one girl s experience with antidepressants. 

Older Antidepressants Tricyclics and Monoamine Oxidase Inhibitors... 

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