Ginseng Monoamine oxidase inhibitors

Synergy of unwanted pharmacological effect ginseng and its products will inhibit the central nervous system (CNS) when they are applied with luminal, chloral hydrate, or ephedrine, which can increase the release of dopamine, noradrenaline, and serotonin in the CNS thus inducing a hypertensive crisis if monoamine oxidase inhibitors (MAOIs) are given simultaneously. 

Interactions of antidepressants with herbal medicines have been reported (53). Ginseng has been reported to cause mania, tremor, and headache when used in combination with conventional monoamine oxidase inhibitors. 

Siberian ginseng is specifically indicated for people with immunode-pression, fatigue, and a lack of vitality and perhaps those who get sick a lot. Unlike echinacea, it is not an immune stimulant rather, it is an immune enhancer and helps restore optimum functioning in the immune system. As it is a monoamine oxidase inhibitor, it is also useful in depression, a condition that often accompanies a severely depleted immune system. 

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