Laser desorption/ionization mass spectrometry

Matrix-assisted Laser Desorption/ Ionization Mass Spectrometry... [Pg.748]

Liquid chromatography/mass spectrometry Lower limit of detection Limit of detection Limit of quantitation Florseshoe crab hemocyanin Liquid scintillation counting Matrix-assisted laser desorption/ ionization mass spectrometry m -Maleimidobenzoy 1-A -Hydroxysuccinimide 1 -Cyclohexyl-3-(2-Morptiolino-ethyl)carbodiimide rnetlio-/ -Toluenesulfonate (same as CDI)... [Pg.12]

Hurst, G. Doktycz, M. Vass, A. Buchanan, M. Detection of bacterial DNA polymerase chain reaction products by matrix assisted laser desorption/ionization mass spectrometry. Rapid. Commun. Mass Spectrom. 1996,10,377-382. [Pg.35]

Hathout, Y. Demirev, P. A. Ho, Y.-P Bundy, J. L. Ryzhov, V. Sapp, L. Stutler, J. Jackman, J. Fenselau, C. Identification of Bacillus spores by matrix-assisted laser desorption ionization-mass spectrometry. Appl. Environm. Microbiol. 1999, 65, 4313-4319. [Pg.37]

Jarman, K. H. Cebula, S. T. Saenz, A. J. Peterson, C. E. Valentive, N. B. Kingsley, M. T. Wahl, K. L. An algorithm for automated bacterial identification using matrix-assisted laser desorption/ionization mass spectrometry. Anal. Chem. 2000, 72, 1217-1223. [Pg.122]

Nordhoff, E. Ingendoh, A. Cramer, R. Overberg, A. Stahl, B. Karas, M. Hillenkamp, F. Crain, P. F. Matrix-assisted laser desorption/ionization mass spectrometry of nucleic acids with wavelengths in the UV and IR. Rapid Comm. Mass Spectrom. 1992, 6,771-776. [Pg.148]

Liang, X. Zheng, K. Qian, M. G. Lubman, D. M. Determination of bacterial protein profiles by matrix-assisted laser desorption/ionization mass spectrometry with high-performance liquid chromatography. Rapid Comm. Mass Spectrom. 1996,10,1219-1226. [Pg.148]

Vaidyanathan, S. Winder, C. L. Wade, S. C. Kell, D. B. Goodacre, R. Sample preparation in matrix-assisted laser desorption/ionization mass spectrometry of whole bacterial cells and the detection of high mass (>20kDa) proteins. Rapid Comm. Mass Spectrom. 2002,16,1276-1286. [Pg.150]

Parker, C. E. Papac, D. L Tomer, K. B. Monitoring cleavage of fusion protein by matrix-assisted laser desorption ionization/mass spectrometry Recombinant HIV-1IIIB p26. Anal. Biochem. 1996, 239, 25-34. [Pg.151]

Arnold, R. J. Reilly, J. P. Observation of tetrahydrofolyl-poly-glutamic acid in bacteria cells by matrix assisted laser desorption/ionization mass spectrometry. Anal. Biochem. 2000,281,45-54. [Pg.200]

Pineda, F. J. Antoine, M. D. Demirev, P A. Feldman, A. B. Jackman, J. Longenecker, M. Lin, J. S. Microorganism identification by matrix-assisted laser/desorption ionization mass spectrometry and model-derived ribosomal protein biomarkers. Anal. Chem. 2003,75,3817-3822. [Pg.275]

Wingerath, T. et al. (1999). Analysis of cyclic and acyclic analogs of retinol, retinoic acid, and retinal by laser desorption ionization-, matrix-assisted laser desorption ionization-mass spectrometry, and UV/Vis. spectroscopy. Anal. Biochem. 272(2) 232-242. [Pg.227]

The most discriminating technique for proving the identity and purity of analyte peak of a chromatogram, especially for analyzing biological samples and natural products, is by using online LC-UV/MS or GC-MS/FTIR methods [15]. Alternatively, one could use a combination of TLC and MS, where direct determination on the TLC plates is made by matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) [16]. [Pg.247]

Many diseases are characterized by the expression of specific proteins1 in some cases, malignant cells yield unique protein profiles when total cellular protein extracts are analyzed by proteomic methods such as two-dimensional gel electrophoresis or matrix-assisted laser desorption ionization-mass spectrometry (MALDI-MS).2 High-throughput proteomic studies may be useful to differentiate normal cells from cancer cells, to identify and define the use of biomarkers for specific cancers, and to characterize the clinical course of disease. Proteomics can also be used to isolate and characterize potential drug targets and to evaluate the efficacy of treatments. [Pg.235]

Schwartz S, Reyzer M, Caprioli R. Direct tissue analysis using matrix-assisted laser desorption/ionization mass spectrometry practical aspects of sample preparation. /. Mass. Spectrom. 2003 38 699-708. [Pg.388]

M. Schiirenberg, K. Dreisewerd, and F. Hillenkamp, Laser Desorption/Ionization Mass Spectrometry of Peptides and Proteins with Particle Suspension Matrices, Anal. Chem., 71, 221 229(1999). [Pg.160]

M.J. Dale, R. Knochenmuss, and R. Zenobi, Graphite/Liquid Mixed Matrices for Laser Desorption/Ionization Mass Spectrometry, Anal. Chem., 68, 3321 3329 (1996). [Pg.160]

Other MS based analytical approaches have occasionally been applied to ancient resin samples, in particular for paint varnishes. Such techniques include FABS (fast atom bombardment mass spectrometry) [35], MALDI (matrix assisted laser desorption-ionization mass spectrometry) and GALDI (graphite assisted laser desorption-ionization mass spectrometry) [36 38]. [Pg.218]

P. Dietemann, M. J. Edelmann, C. Meisterhans, C. Pfeiffer, S. Zumbuhl, R. Knochenmuss, R. Zenobi, Artificial photoaging of triterpenes studied by graphite assisted laser desorption/ ionization mass spectrometry, Helv. Chim. Acta, 3, 1766 1777. [Pg.235]

J. Shiea, M.-Z. Huang, H.-J. HSu, C.-Y. Lee, C.-H. Yuan, I. Beech, and J. Sunner. Electrospray-Assisted Laser Desorption/Ionization Mass Spectrometry for Direct Ambient Analysis of Solids. Rapid Commun. Mass Spectrom., 19(2005) 3701-3704. [Pg.76]

M. Karas, U. Bahr, and F. Hillenkamp. UV Laser Desorption/Ionization Mass Spectrometry of Proteins in the 100,000 Dalton Range. Int. J. Mass Spectrom. Ion Proc., 92(1989) 231-242. [Pg.79]

J. Bai, X. Liang, Y. H. Liu, Y. Zhu, and D. M. Lubman. Characterization of Two New Matrices for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry. Rapid Commun. Mass Spectrom., 10(1996) 839-844. [Pg.80]

J. Yu, E. R. Butelman, J. H. Woods, B. T. Chait, and M. J. Rreek. In Vitro Biotransformation of Dynorphin A (1-17) is Similar in Human and Rhesus Monkey Blood as Studied by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry. J. Pharmacol. Exp. Then, 279(1996) 507-514. [Pg.81]

O. A. Mirgorodskaya, Y. P. Kozmin, M. I. Titov, R. Kbmer, C. P. Sonksen, and P. Roepstorff. Quantitation of Peptides and Proteins by Matrix-Assisted Laser Desorption/ Ionization Mass Spectrometry Using lsO-Labeled Internal Standards. Rapid Commun. Mass Spectrom., 14(2000) 1226-1232. [Pg.81]

T. B. Fanner and R. M. Caprioli. Determination of Protein-Protein Interactions by Matrix-Aassisted Laser Desorption/Ionization Mass Spectrometry. J. Mass Spectrom., 33(1998) 697-704. [Pg.81]

B. Warscheid and C. Fenslau. A Targeted Proteomics Approach to the Rapid Identification of Bacterial Cell Mixtures by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry. Proteomics, 4(2004) 2877-2892. [Pg.274]

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