Proteins cellular

Nakamura K, Go N. 2005. Function and molecular evolution of multicopper blue proteins. Cellular Mol Life Sci 62 2050-2066. 

Dutta-Roy, A.K. (2000) Cellular uptake of long chain fatty acids role of membrane associated fatty acid binding/transport proteins. Cellular and Molecular Life Sciences (in press). 

Kennedy, M.W. and Beauchamp, J. (2000) Sticky finger interaction sites on cytosolic lipid binding proteins Cellular and Molecular Life Sciences 57, 1379-1387. 

Horton, P., and Nakai, K. (1997). Better prediction of protein cellular localization sites with the k nearest neighbor classifier. Intell. Syst. Mol. Biol. 5, 147-152. 

Li J, Kogan M, Knight SAB, et al. 1999. Yeast mitochondrial protein, Nfslp, coor-dinately regulates iron-sulfur cluster proteins, cellular iron uptake, and iron dis-tribntion. J Biol Chem 274 33025-34. 

Paracetamol is a widely used analgesic, which causes liver necrosis and sometimes renal failure after overdoses in many species. The half-life is increased after overdoses because of impaired conjugation of the drug. Toxicity is due to metabolic activation and is increased in patients or animals exposed to microsomal enzyme inducers. The reactive metabolite (NAPQI) reacts with GSH, but depletes it after an excessive dose and then binds to liver protein. Cellular target proteins for the reactive metabolite of paracetamol have been detected, some of which are enzymes that are inhibited. Therefore, a number of events occur during which ATP is depleted, Ca levels are deranged, and massive chemical stress switches on the stress response. 

Cordwell SJ, Nouwens AS, Verrills NM, Basseal DJ, Walsh BJ. Subproteo-mics based upon protein cellular location and relative solubilities in conjunction with composite two-dimensional electrophoresis gels. Electrophoresis 2000 21 1094-1103. 

Primary Information Secondary Information Protein-cellular Information Inter-cellular Information Neuron-organ Information... 

For the production of many recombinant proteins, cellular insolubility is a major problem because it is often difficult to achieve biological activity starting with such products (57). However, because the polyphenolic protein produced in vivo is a preadhesive, in vitro activation to the adhesive form is required. Therefore, in vivo insolubility may actually be desirable in the case of the polyphenolic protein because this could result in increased resistance to yeast proteases and better product uniformity and quantity. 

After the light-catalyzed reaction, all-mins-rctinal is released, which in turn is reduced to all-/ntm-retinol. To be used again by opsin, the all-/nins-retinol must be converted to I l-eis-rclinol. Isomerization occurs in the pigment epithelium of the retina. Oxidation of I l-cis-relinol to I -cis-relrnaldchyde occurs while retinol is bound to the protein cellular retinaldehyde-binding protein (CRALBP) by a microsomal enzyme in the pigment epithelium. ... 

Rose, A. and Meier, I. (2004) Scaffolds, levers, rods and springs diverse cellular functions of long coiled coil proteins. Cellular and Molecular Life Sciences, 61(16), 1996-2009. 

Tolttier Y, Devys D, Imbert G, Saudou G> An I, Lutz Y, et al. Protein cellular localization of the Huntington s disease protein and discrimination of the normal and mutated form. Nat Genet 1995 10 104-10. 

Tullis, J.L. (Proceedings 9th) Conference on the Plasma Protein Cellular Elements of the Blood, p. 17-18. Cambridge, MA, Protein Foundation, 1954. 

Zimmerman, A. W., and J. H. Veerkamp. 2002. New insights into the structure and function of fatty acid-binding proteins. Cellular and Molecular Life Science 59 1096-1116. 

Kempnh, R, Zingg, J.M., Ricciarelli, R., Hierl, M., Saxena, S., and Azzi, A., Cloning of novel human SEC14p-like proteins cellular localization, ligand binding and functional properties. Free Radic. Biol. Med. 34, 1458-1472, 2003. 

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