Mass spectrometry fast atom-bombardment

Caprioli, R.M., Continuous-Flow Fast Atom Bombardment Mass Spectrometry, Wiley, New York, 1990. 

FABMS Fast-atom bombardment mass spectrometry... 

E. Davoli, R. Fanelli and R. Bagnati, Purification and analysis of dmg residues in urine samples by on-line immunoaffinity cliromatography/bigh-performance liquid cliro-matography/continuos-flow fast atom bombardment mass spectrometry . Anal. Chem. 65 2679-2685 (1993). 

Fast atom bombardment mass spectrometry and related techniques. J. M. Miller, Adv. Inorg. Chem. Radiochem., 1984,28,1 (118). 

FIG. 14 Distribution of alkanemono- and disulfonates in a commercial product (Hostapur SAS 93) by fast atom bombardement-mass spectrometry (FAB-MS). Conditions glycerol/H20, KCI, 3-nitrobenzylalcohol. 

The treatment of sucrose with anhydrous HF89 results in the formation of a complex mixture of pseudooligo- and poly-saccharides up to dp 14, which were detected by fast-atom-bombardment mass spectrometry (FABMS). Some of the smaller products were isolated and identified by comparison with the known compounds prepared86 88 a-D-Fru/-1,2 2,1 -p-D-Fru/j (1), either free or variously glucosylated, was a major product, and this is in accord with the known stability of the compound. The mechanism of formation of the products in the case of sucrose involves preliminary condensation of two fructose residues. The resultant dianhydride is then glucosylated by glucopyranosyl cation.89 The characterization of this type of compound was an important step because it has permitted an increased understanding of the chemical nature of caramels. 

In line with the policy of Advances to provide periodic coverage of major developments in physical methodology for the study of carbohydrates, A. Dell (London) here surveys the use of fast-atom-bombardment mass spectrometry in application to carbohydrates. This technique has achieved rapid prominence as the soft ionization technique of choice for structural investigation of complex carbohydrate sequences in biological samples. The author s extensive personal involvement in this field makes her chapter a critical, state-of-the-art overview for the specialist, as well as a valuable primer for the reader unfamiliar with this technique. 

Oka, H. et al., Identification of unlawful food dyes by thin-layer chromatography-fast atom bombardment mass spectrometry, J. Chomatogr. A, 674, 301, 1994. 

Drucker, D. B. Aluyi, H. S. Boote, V. Wilson, J. M. Ling, Y. Polar lipids of strains of Prevotella, Bacteroides and Capnocytophaga analyzed by fast atom bombardment mass spectrometry. Microbios 1993, 75, 45-56. 

Drucker, D. B. Fast atom bombardment mass spectrometry of phospholipids for bacterial chemotaxonomy. ACS Symp. Ser. 1994, 541,18-35. 

Heller, D. N. Cotter, R. J. Fenselau, C. Uy, O. M. Profiling of bacteria by fast atom bombardment mass spectrometry. Anal. Chem. 1987,59, 2806-2809. 

Other MS based analytical approaches have occasionally been applied to ancient resin samples, in particular for paint varnishes. Such techniques include FABS (fast atom bombardment mass spectrometry) [35], MALDI (matrix assisted laser desorption-ionization mass spectrometry) and GALDI (graphite assisted laser desorption-ionization mass spectrometry) [36 38]. 

S. Beranova-Giorgianni and D. M. Desiderio. Fast Atom Bombardment Mass Spectrometry of Synthetic Peptides. In Methods in Enzymology Solid-Phase Peptide Synthesis, ed. G. B. Fields. Methods in Enzymology 289. Academic Press, San Diego, 1997, 478-499. 

M. Barber, R. S. Bordoli, G. J. Elliott, R. D. Sedgwick, and A. N. Tyler. Fast Atom Bombardment Mass Spectrometry. Anal. Chem., 54(1982) 645A-657A. 

H. Oka, Y. Ikai, T. Ohno, N. Kawamura, J. Hayakawa, K. Harada, and M. Suzuki. Identification of Unlawful Food Dyes by Thin-Layer Chromatography-Fast Atom Bombardment Mass Spectrometry. J. Chromatogr., A674(1994) 301-307. 

L. M. Mallis, H. M. Wang, D. Loganathan, and R. J. Linhardt. Sequence Analysis of Highly Sulfated, Heparin-Derived Oligosaccharides Using Fast Atom Bombardment Mass Spectrometry. Anal. Chem., 61(1989) 1453-1458. 

R. M. Caprioli and W. T. Moore. Continuous-Flow Fast Atom Bombardment Mass Spectrometry. In Methods in Enzymology Mass Spectrometry, ed. J. A. McCloskey. Methods in Enzymology 193, Academic Press, San Diego, 1990, 214-237. 

J.M. Gilliam, P.W. Landis and J.L. Occolowitz, On-line accurate mass measurement in fast atom bombardment mass spectrometry, Anal. Chem., 56 (1984) 2285-2288. 

Y. Ito, T. Takeuchi, D. Ishii, M. Goto and T. Mizuno, Direct coupling of micro high performance liquid chromatography with fast atom bombardment mass spectrometry. II Application to gradient elution of bile acids, J. Chromatogr., 385 (1986) 201-209. 

Note. Abbreviations g.l.c., gas-liquid chromatography e.i.-m.s., electron-impact mass spectrometry c.i.-m.s., chemical-ionization mass spectrometry h.p.l.c., high-performance liquid chromatography h.p.a.e., high pH anion-exchange f.a.b.-m.s., fast-atom-bombardment mass spectrometry l.s.i.-m.s., liquid secondary-ion mass spectrometry n.O.e., nuclear Overhauser enhancement. Details of these methodologies are given in Ref. (3). 

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