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Image probing

Ferroelectric—polymer composite devices have been developed for large-area transducers, active noise control, and medical imaging appHcations. North American Philips, Hewlett-Packard, and Toshiba make composite medical imaging probes for in-house use. Krautkramer Branson Co. produces the same purpose composite transducer for the open market. NTK Technical Ceramics and Mitsubishi Petrochemical market ferroelectric—polymer composite materials (108) for various device appHcations, such as a towed array hydrophone and robotic use. Whereas the composite market is growing with the invention of new devices, total unit volume and doUar amounts are small compared to the ferroelectric capacitor and ferroelectric—piezoelectric ceramic markets (see Medical imaging technology). [Pg.209]

Most disease-specific molecular and cellular processes involve low concentrations and have low capacities. Therefore, molecular imaging requires highly sensitive imaging modalities to detect and quantify the imaging probes as it is done with short-lived radioisotopes. Optical imaging and ultrasound are next in sensitivity. MRI would require too high contrast agent concentrations... [Pg.1325]

A single cell layer of an excised piece of onion epidermis was selected as a test object for this micro-coil, (Figure 2.1.14), and an imaging experiment was carried out, similar to the one by Mansfield et al., who used a laboratory-made micro-coil probe and gradient system [31]. Other micro-coil types, e.g., volume coils or coils that are immersed into the objects, can be adapted to specific applications and mounted on commercial imaging probes. [Pg.71]

Fig. 2.1.17 Conventional NMR microscopy gradient system (Micro2.5, 2.5 C cm-1 A-1, 40-mm inner diameter) (right) and a conventional MAS probe (left). The probe is mounted into the separate gradient system instead of the original imaging probe. Fig. 2.1.17 Conventional NMR microscopy gradient system (Micro2.5, 2.5 C cm-1 A-1, 40-mm inner diameter) (right) and a conventional MAS probe (left). The probe is mounted into the separate gradient system instead of the original imaging probe.
Most of the commercially available NMR imaging probes have an accessible clear bore above and below the coil, which can be used for remote signal encoding. A detection-only probe can be inserted from the top into the bore of the magnet in such a way that the detection coil sits immediately above the imaging coil [Figure 2.6.5 (c)]. Similarly, an rf probe with a narrow body can be built that can be inserted into the... [Pg.150]

Over the last 10 years there has been a major initiative to bring HTS into the academic community. The NIH roadmap has a mission to build a better toolbox for medical research in the twenty-first century and to empower the research community to use small molecule compounds in their research, whether as tools to perturb genes and pathways, as imaging probes in basic or clinical applications, or as starting points to the development of new therapeutics for human disease. [Pg.71]

Wang M, Gao M, Miller KD et al (2009) Simple synthesis of carbon-11 labeled styryl dyes as new potential PET RNA-specific, living cell imaging probes. Eur J Med Chem 44 2300-2306... [Pg.57]

An interesting imaging probe Id that can selectively target bacteria was recently reported by Smith et al. [31] also based on a heptamethine chromophore. The probe is composed of a bacterial affinity group, which is a synthetic zinc (II) coordination complex that targets the anionic surfaces of bacterial cells and a near infrared dye. The probe allowed detection of Staphylococcus aureus in a mouse leg infection model using whole animal near-infrared fluorescence imaging. [Pg.71]

Lee JS, Kang NY, Kim YK, Samanta A, Feng S, Kim HK, Vendrell M, Park JH, Chang YT (2009) Synthesis of a BODIPY library and its application to the development of live cell glucagon imaging probe. J Am Chem Soc 131 10077-10082... [Pg.185]

PARACEST agents are particularly well adapted for the development of responsive probes, since the rate of exchange and the chemical shift of the protons leading to a PARACEST effect depend on various physico-chemical parameters. We will discuss several examples from this field in the following section on Responsive Imaging Probes. ... [Pg.100]

DESIGN CONSIDERATIONS TOWARDS SIMULTANEOUSLY RADIOLABELED AND FLUORESCENT IMAGING PROBES INCORPORATING METALLIC SPECIES... [Pg.131]

Fig. 6. Metallic imaging probes (a) and the fluorescence imaging (b) at the uptake of the Re(I) analog in tumor cells. Images adapted from Ref. (29). Fig. 6. Metallic imaging probes (a) and the fluorescence imaging (b) at the uptake of the Re(I) analog in tumor cells. Images adapted from Ref. (29).
Fig. 8. Schematic representation of a pyrene-conjugated multimodality imaging probe prototype. Fig. 8. Schematic representation of a pyrene-conjugated multimodality imaging probe prototype.
Fig. 11. Schematic representations of imaging probe components for 68Ga delivery. Fig. 11. Schematic representations of imaging probe components for 68Ga delivery.
D. Applications of Metalloporphyrins as Multimodal, Optical, and/or Radioactive Imaging Probes... [Pg.156]

Fig. 31. Proposed design for core-shell multimodal imaging probes incorporating iron nanoparticles. Fig. 31. Proposed design for core-shell multimodal imaging probes incorporating iron nanoparticles.
Scheme 4. Synthesis of the radiolabeled imaging probe [18F]FDG 28 in a PDMS-based microfluidic reactor... Scheme 4. Synthesis of the radiolabeled imaging probe [18F]FDG 28 in a PDMS-based microfluidic reactor...
Lee CC, Sui GD, Elizarov A, Shu CYJ, Shin YS, Dooley AN, Huang J, Dari-don A, Wyatt P, Stout D, Kolb HC, Witte ON, Satyamurthy N, Heath JR, Phelps ME, Quake SR, Tseng HR (2005) Multistep Synthesis of a Radio-labeled Imaging Probe Using Integrated Microfluidics. Science 310 1793— 1796... [Pg.19]

References [52-54] do not include any data directly comparing squaraine rotaxanes with common cyanine dyes such as Cy5 (GE Healthcare) and Alexa 647 (Life Technologies). Nevertheless, from the available data it can be concluded that squaraine rotaxanes are remarkably resistant to chemical and photochemical degradation, and likely to be very useful as a versatile fluorescent scaffold for constructing various types of highly stable, red and near infrared (NIR) imaging probes and labels. [Pg.170]

An overview of the synthesis, structure, photophysical properties, and applications of squaraine rotaxanes as fluorescent imaging probes and chemosensors is provided in a recent review [67]. Although a variety of squaraine dyes form rotaxanes with the molecular cage 25 or with a tetralactam macrocyclic system introduced by Leigh and co-workers [16, 17], there is no evidence in the literature that conventional cyanine dyes can be embedded in these macrocycles. [Pg.180]


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See also in sourсe #XX -- [ Pg.283 ]




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High-temperature imaging probe

Imaging atom-probe

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Imaging probes

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Imaging probes cantilevers

Imaging probes contact mode

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Imaging probes force regimes

Imaging probes liquid environments

Imaging probes sample roughness

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Imaging scanning probe microscopy

In-Situ Scanning Probe Microscopies Imaging and Beyond

Magnetic resonance imaging probes

Molecular imaging probes

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Molecular imaging strategies probes

Multistep Synthesis of a Radiolabeled Imaging Probe

Optical imaging with fluorescence probes

Probe calibration and image artefacts

Probes cellular imaging

Radiolabeled imaging probe, multistep

Radiolabeled imaging probe, multistep synthesis

Radionuclides for PET and SPECT Molecular Imaging Probes

Responsive Imaging Probes

Scanning Probe Microscopic image

The imaging probe

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