Molecular imaging strategies probes

Cheng, Z., Winant, R. C., and Gambhir, S. S. (2005). A new strategy to screen molecular imaging probe uptake in cell culture without radiolabeling using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. J. Nucl. Med. 46 878-886. 

The key challenge for the successful use of NMR velocity-imaging techniques to characterize fluid flow properties is the interpretation of the measured parameters. Different experimental strategies provide information about flow processes at different spatial and dynamic scales in porous media. In principle, the flow velocity can be probed either as a local quantity with an image resolution below the pore level,2425 or as a macroscopic flow property corresponding to local volume and temporal averages of fluid molecular displacements.26 One must develop a suitable methodology to correctly determine the parameters that best describe the properties of interest. 

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