Optical imaging with fluorescence probes

HabiboUahi, P., et al. Optical imaging with a cathepsin B activated probe for the enhanced detection of esophageal adenocarcinoma by dual channel fluorescent upper GI endoscopy. Theranostics 2(2), 227 (2012)... 

Optical imaging with collinear optical coherence and confocal fluorescence microscopy (OCM-CFM). This noninvasive imaging technique combines the use of reflection confocal microscopy in tandem with optical coherence microscopy to characterize scaffolds and tissue constructs. It can probe the interior of scaffolds with the same resolution as conventional laser scanning confocal microscopy but with greater sensitivity (P). 

The specificity of the detection scheme was demonstrated by correlating optical images of the nanowire barcodes acquired with and without fluorescence excitation. In this manner, multiple probes could be used simultaneously for the detection of a diverse set of analytes. 

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