Diabetic ulcers

Regranex (becaplermin, rPDGF) Neuropathic diabetic ulcers Janssen Ortho-McNeil... 

Diabetic ulcers Ulcers (e.g. diabetic leg ) caused by complications of diabetes... 

Regranex Platelet-derived growth factor Diabetic ulcers 7... 

Certain forms of dwarfism, type II diabetes, kidney disease, growth hormone insensitivity, cachexia, amyotrophic lateral sclerosis, peripheral neuropathy Wound healing, skin ulcers Diabetic ulcers, wound healing... 

Decubitus ulcer (e.g. bed sores, pressure sores) Diabetic ulcers Varicose ulcers Rodent ulcers Peptic ulcers Ulcer due to continuous pressure exerted on a particular area of skin often associated with bed-ridden patients Ulcers (e.g. diabetic leg ) caused by complications of diabetes Due to defective circulation, sometimes associated with varicose veins An ulcerous cancer (basal cell carcinoma), usually affecting the face Ulcer of the digestive tract, caused by digestion of the mucosa by acid and pepsin may occur in e.g. the duodenum (duodenal ulcer), or the stomach (gastric ulcer)... 

Topical sucralfate (4-10%) is also useful in management of decubitus ulcer, diabetic ulcers, chemical and thermal burns, radiation induced skin damage, vaginal ulceration, oral and genital ulceration. 

Sodium Hyaluronate Cream For leg ulcer, diabetic ulcer etc. 

N.A. Fixed oil, insulin-like peptide, mormordin, charantin, mormordicine." Treat diabetes, ulcers, urinary stones, a stomach tonic, induces menstruation. 

Shifts in the cutaneous microbiome have also been noted in chronic ulcer disease, such as those caused by venous stasis or diabetes (175). Patients with chronic ulcers treated with antibiotics have been shown to have an increased abundance of Pseudomonadaceae while an increase in Streptococcaceae has been noted in diabetic ulcers (175). A longitudinal shift in wound microbiota has also been shown to coincide with impaired healing in diabetic mice, and may interact with aberrantly expressed host cutaneous defense response genes leading to ulcerogenesis (176). When compared to controls, the feet of diabetic men has also been noted to have decreased populations of Staphylococcus species, a relative increase in the population of S. aureus and increased bacterial diversity, which may increase the risk for wound infections in diabetic patients (177). 

Bromelain has found application in a wide variety of inflammatory conditions. These include thrombophlebitis, skeletal muscle injuries, hematomas, oral inflammations, diabetic ulcers, and athletic injuries [2,5,88,93]. 

The FDA has approved several cell therapy products as devices for skin replacements for the treatment of acute (e.g., burns) and chronic (e.g., diabetic ulcers) inflammatory skin disorders. 

Regranex Becaplermin Ortho-McNeil 12/1997 Diabetic ulcers S. cerevisiae... 

Miller, M.S. Use of topical recombinant human platelet-derived growth factor-BB (becaplermin) in healing of chronic mixed arteriovenous lower extremity diabetic ulcers. J. Foot Ankle Surg. 1999, 38 (3), 227-231. 

The Effect of Sodium Carboxymethylcellulose Gel in Patients with Non-healing Lower Extremity Diabetic Ulcers, American College of Surgeons, Chicago, IL, October 13, 1997. 

Trade names PDGF (Novartis) Regranex (Janssen) (Cilag AG) Indications Diabetic ulcers less than or equal to 5 cm2 Category Platelet derived growth factor-BB Half-life N/A... 

Baccharis genistelloides Lam. = Baccharis trimera (Lam.) Pers. ( Carqueja , Charara ) is used for liver disorders and as an antithermic. Other popular uses in Brazil include digestive disorders, malaria, diabetes, ulcers, sore throat and tonsilitis, anaemia, diarrhoea, indigestion, urinary inflammation, intestinal worms and leprosy [16,17],... 

Becaplennin rhPDGF Diabetic ulcers Increased mortality secondary to malignancy, aythmatous rashes... 

The efficacy of Osteoset as a bone graft substitute has been questioned [32] and the evidence base for use in treating diabetic ulcer infections is sparse but anecdotally UK and USA centres are reporting positive results. This is clearly an area for further research. 

Diabetics tend to have poor circulation, and they are often afflicted with open sores, called diabetic ulcers. What is the relationship between these ulcers and flies ... 

Flies lay eggs, which develop into maggots, which hatch as flies. Diabetic ulcers are notoriously hard to heal, but maggots can be very helpful in the healing process. 

Choi, J.S., Leong, K.W., Yoo, H.S., 2008. In vivo wound healing of diabetic ulcers using electrospun nanofibres immobihzed with human epidermal growth factor (EGF). Biomaterials 29 (5), 587—596. 

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