Baccharis trimera

One of the most exiting findings in this area is perhaps the isolation of Bt-CD, a neoclerodane diterpenoid from Baccharis trimera (Less) DC or carqueja (Brazil) used to treat rheumatism and diabetes that shows anti-phospholipase A2 activity (11). Note also the anti-phospholipase A2 and anti-inflammatory activity of Santolina chamaecy-parissus (12). Cirsium japonicum DC, Crossotephium chinense L. Makino, Inula chinensis Rupr. ex Maxim., and Sigesbeckia orientalis L. are used in Asia for the treatment of inflammatory conditions. 

Januario AH, Simone LS, Silvana M, et al. Neo-clerodane diterpenoid, a new metallo-protease snake venom inhibitor from Baccharis trimera (Asteraceae) anti-proteolytic and anti-hemorrhagic properties. Chem Biol Interact 2002 150 243-251. 

Baccharis genistelloides Lam. = Baccharis trimera (Lam.) Pers. ( Carqueja , Charara ) is used for liver disorders and as an antithermic. Other popular uses in Brazil include digestive disorders, malaria, diabetes, ulcers, sore throat and tonsilitis, anaemia, diarrhoea, indigestion, urinary inflammation, intestinal worms and leprosy [16,17],... 

Fig. 2. Absorption UV/Visible spectra. A, Baccharis articulata (Ba) B, Baccharis trimera (Bt) populations. BA, Buenos Aires COR, Coriientes ER, Entre Rios SF, Santa Fe. Numbers indicate when there is more than one population of the same species...

Gene, R.M, Cartana, C., Adzet, T., Marin, E., Parella, T. Canigueral, S. (1996). Anti-Inflammatoiy and Analgesic Activity of Baccharis trimera Identification of its Active Constituents. Planta Medica, Vol 62, pp. 232-235, ISSN 0032-0943. 

Stoicke, H. Leng-Peschlow, E. (1987). Characterization of flavonoids from Baccharis trimera and their antihepatotoxic properties. Planta Medica, Vol 53, pp. 37-39, ISSN 0032-0943. 

Diterpene from Baccharis trimera with a Relaxant Effect on Rat Vascular Smooth Muscle. Phytochemistry, Vol 55, No. 6 (November 2000), pp. 617-619, ISSN 0031-9422. 

Herz, W., A.-M. Pilotti, A.-C. Soderholm, I.K. Shuhama, and W. Vich-newski New e /-clerodane-type diterpenoids from Baccharis trimera. J. Org. Chem. 42, 3913 (1977). 

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