Varicose ulcers

Varicose ulcers Due to defective circulation, sometimes associated with varicose veins... 

Decubitus ulcer (e.g. bed sores, pressure sores) Diabetic ulcers Varicose ulcers Rodent ulcers Peptic ulcers Ulcer due to continuous pressure exerted on a particular area of skin often associated with bed-ridden patients Ulcers (e.g. diabetic leg ) caused by complications of diabetes Due to defective circulation, sometimes associated with varicose veins An ulcerous cancer (basal cell carcinoma), usually affecting the face Ulcer of the digestive tract, caused by digestion of the mucosa by acid and pepsin may occur in e.g. the duodenum (duodenal ulcer), or the stomach (gastric ulcer)... 

Acetyl-ft-methyl choline 195 Cation Vasodilator, muscle relaxant radiculitis, varicose ulcers, discogenic low-back arthritis 141... 

A healed varicose ulcer has been observed to break down after treatment (41). 

El-Ghobarey AF, Mavrikakis M, Morgan I, Mathieu JP. Delayed healing of varicose ulcer with levamisole. BMJ 1977 1(6061) 616. 

Trypsin/balsam peru/castor oil is a topical enzyme combination that physiologically debrides tissue and improves epi-thelization by reducing premature epithelial desiccation and comiflcation. It is used in acute and chronic conditions such as varicose ulcers, decubital ulcers, eschar, dehiscent wounds and sunburn relieves pain and promotes healing debrides eschar and necrotic tissue stimulates vascular bed improves epithelization and reduces odor from necrotic wounds. 

Its actions on the cardiovascular system are more marked and pronounced than on the genitourinary and gastro-intenstinal systems. It has been used successfully to terminate attacks of supraventricular paroxysmal tachycardia. It is found to be more muscarinic than nicotinic in its actions. It is frequently employed to afford vasodilation in vasospastic conditions, namely chronic varicose ulcers, cold exposure and phlebits. 

Leaf preparations used in European traditions for eczema, varicose veins, supportive treatment of varicose ulcers, phlebitis, thrombophlebitis, hemorrhoids, menstrual spastic pain, soft tissue swelling from bone fracture and sprains, and other uses. Effectiveness of leaf preparation claims is unsubstantiated. ... 

M/sce//aneons - Asthenia, back pain, bacterial infection, chest pain, fever, flu-like symptoms, flushing, hot flushes, intermittent claudication, leg ulcer, malaise, moniliasis, ptosis, rigors, varicose vein, viral infection. 

For debridement of necrotic tissue and liquefication of slough in acute and chronic lesions such as pressure ulcers, varicose, diabetic, and decubitus ulcers, burns, postoperative wounds, pilonidal cyst wounds, carbuncles, and miscellaneous traumatic or infected wounds. Also stimulates vascular bed activity to improve epithelization. 

It is a sclerosing agent for bleeding oesophageal varices, varicose veins, bleeding gastroduodenal ulcers etc. 

Before commencing the sessions the patients were assessed by physical examination and full medical history including age, sex, occupation, residence, special habits of medical importance with particular emphasis on the history of the underlying disease including duration of ulcer, mode of onset, ulcer pain, history of deep vein thrombosis or varicose veins, trauma, lump, varicosities, contact dermatitis and symptoms suggestive of ischaemia. Photographic reference of ulcer and ulcer area measurements were carried out at the commencement of treatment and during the follow up laser therapy, which continued for 6 months. 

Calendula is stated to possess antispasmodic, mild diaphoretic, anti-inflammatory, antihemorrhagic, emmenagogue, vulnerary, styptic, and antiseptic properties. Traditionally, it has been used to treat gastric and duodenal ulcers, amenorrhea, dysmenorrhea and epistaxis crural ulcers, varicose veins,... 

Marshmallow has demulcent, expectorant, emollient, diuretic, antilithic, and vulnerary properties. Traditionally, it has been used internally for the treatment of respiratory catarrh and cough, peptic ulceration, inflammation of the mouth and pharynx, enteritis, cystitis, urethritis and urinary calculus, and topically for abscesses, boils, and varicose and thrombotic ulcers. 

The infusion of 1 ounce of the flowers or herb to 1 pint boiling water is prescribed both for internal use in 1-2 tablespoonful doses, and externally as a lotion for chronic ulcers and varicose veins. The infusion is also given to children (in doses according to age) suffering from measles and other feverish and eruptive complaints. Sprained muscles gain relief from the hot fomentation. Marigold is frequently combined with Witch Hazel when a lotion is required. 

Vasodilators such as naftidrofuryl (Praxilene) and oxpentifylline (pentoxifylline) (Trental) increase blood flow to skin rather than muscle they have also been successfully used in the treatment of venous leg ulcers (varicose and traumatic). 

Indications 1) Yang qi insufficiency with concomitant blood vacuity, external invasion of cold evils, 2) cold entering the channels and network vessels. Thromboangiitis obliterans, varicose veins, frostbite (before skins swells and cracks or after healed), callouses and corns, dysmenorrhea, hernia, colic testalgia, chronic rheumatoid arthritis, Raynaud s disease, fibromyalgia, sciatica, peptic ulcer, chronic urticaria, midline pain, chilblains, and gangrene... 

Fig. 10.6 Diabetic Ulcer varicose treatment using Nanoskin . After 3 months we can see the completely healing...

Nitrofurazone (Furacin) has over the years been used in solution or powder for leg ulcers and varicose eczema. Many cases of contact allergy occurred and subsequently descreased the dermatologic use of this drug topically (Braun and ScHUTZ 1968). Each individual case tends to be dramatic, i.e., the extent and severity of the dermatitis is clinically striking, so that, unlike neomycin dermatitis, diagnosis presents no problem. The frequency of the dermatitis has probably been exaggerated, and may be less than that due to neomycin. 

It should be stated that venous leg ulcers are chronic and there is no medication or surgery to cure the disease other than the compression therapy. A sustained graduated compression mainly enhances the flow of blood back to the heart, improves the functioning of valves and calf muscle pumps, reduces oedema, and prevents the swelling of veins. Mostly elderly people are prone to develop DVT, varicose veins, and venous leg ulcers. Venous leg ulcers are the most frequently occurring type of chronic wound, accounting for 80-90% of all lower extremity ulceration. 

Small intracutaneous or reticular veins are present in over half of the world s Westernized population (Krijnen et al. 1998). Even without treatment, only a minority of these individuals develop clinically relevant varicosis. Clinically relevant varicose veins which give rise to complaints and complications are present in approximately 10% of the Western population (Madar et al. 1986). Approximately 1% of the population suffers from leg ulceration at some point in their lives (Callam 1992). There is evidence of venous disease in 60% to over 90% of leg ulcers (Callam 1992). 

Da Silva A, Widmer LK, Martin H, et al. (1974) Varicose veins and chronic venous insufficiency. Vasa 2 118-125 Fagrell B (1982) Microcirculatory disturbances - the final cause for leg ulcers Vasa 11 101-103... 

Venous ulcers (including healed ulcers), deep vein thromhosis, superficial thrombophlebitis, varicose veins with severe edema, postthrombotic syndrome, mild lymphedema... 

When venous valves are weakened and allow regurgitation of blood, there is an abrupt increase in venous pressure (Alguire and Mathes, 1997 Beebe-Dimmer et al., 2005 Hjelmstedt, 1968). The increased pressure and resulting venous hypertension are the primary cause of chronic venous insufficiency (CVI) (Belcaro et al., 1989 Browse, 1986 Browse and Bumand, 1982 Hjelmstedt, 1968). The continued prevalence of hypertension leads to dilation of the incompetent veins, resulting in varicose veins like those shown in Figure 20.12, the most conunon manifestation of CVI (Alguire and Mathes, 1997 Bhutia et al., 2008 McLafferty et al., 2007). If left untreated, CVI can cause dramatic cosmetic changes in skin, lower limb pain, edema, deep vein thrombosis, and ulcers (Adhikari et al., 2000 McLafferty et al., 2007 Robertson et al., 2008 Schoonover et al., 2009 Tran and Meissner, 2002 Van Den Bos and... 

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