Full text database

Typical bibliographic databases are the CA File of Chemical Abstracts Service CAS) or Medline of the US National Library of Medicine. Most electronic journals provide articles as full-text files, e.g., the Journal of the American Chemical Society ( ACS). 

Chemical Substructure Databases. Several patent databases are searchable by chemical substmcture (99). These are designed to give higher relevance of retrieval when searching chemical compounds than the bibHographic or full-text databases. 

GORE. The CORE Electronic Chemistry Library is a joint project of Cornell University, OCLC (On-line Computer Library Center), Bell Communications Research (Bellcore), and the American Chemical Society. The CORE database will contain the full text of American Chemical Society Journals from 1980, associated information from Chemical Abstracts Service, and selected reference texts. It will provide machine-readable text that can be searched and displayed, graphical representations of equations and figures, and full-page document images. The project will examine the performance obtained by the use of a traditional printed index as compared with a hypertext system (SUPERBOOK) and a document retrieval system (Pixlook) (6,116). 

NERAC, bibhography. Full Text Database Searching, pub. no. PB92-860469, ToUand, Conn., 1992. 

Searching of one or more on-line databases is a technique increasingly used ia novelty studies. The use of such databases enables the searcher to combine indexing parameters, including national and international classifications natural language words ia the full text of patents, ia their claims, or ia abstracts suppHed by iaventor and by professional documentation services and indexing systems of various sorts. Because the various patent databases have strengths and weaknesses that complement each other, the use of multiple databases is thus pmdent, and is faciUtated by multifile and cross-file techniques provided by the various on-line hosts. 

Full-Text Patent Databases. The LEXPAT database on the LEXIS— NEXIS system, the first commercially available full-text patent file, receives its greatest use from patent attorneys and has been relatively unused by other patent information speciaUsts. This may be attributed to search software that is quite different from the type familiar to information speciaUsts, no matter what their preferred host system. This situation has changed with dialog s release of the PATEULL files followed by STN s USPATEULL, both searchable by familiar Boolean techniques and featuring greater... 

For purposes of tracking statistics on database classes, several subclasses for word-oriented and number-oriented databases have been estabhshed. Word-oriented databases can be subdivided into bibhographic, patent/trademark, directory, dictionary, full-text, and other categories. The first pubHcly... 

The percentage of word-oriented databases continues to increase at a faster pace than numeric databases. The number of image databases was 358 in 1992, greater than twentyfold increase from 1989. Audio databases rose from 1 in 1988 to 109 in 1992. A breakdown of the subclasses within word-oriented databases is given in Table 3, showing that full-text databases have surpassed bibhographic ones. Directory databases are the third most numerous. 

Subject Categories. The deterrninant for user selection of a database is usually subject matter. That is, when chemical information is desired, a chemical database is selected. The form or media of the database is of secondary importance. The type of search may dictate the need for a full-text or statistical database. If none exists, however, a bibhographic database in the topic area may be used to locate full-text or numeric compilations in hard-copy form. 

Almost all the articles selected for the database can be ordered in full text through our document delivery department. 

Web in the life of the medicinal chemist. One may see the development of alerting services for the primary medicinal chemistry journals. The Web-based information search process could be replaced by a much more structured one based on metadata, derived by automated processing of the original full-text article. To discover new and potentially interesting articles, the user subscribes to the RSS feeds of relevant publishers and can simply search the latest items that appear automatically for keywords of interest. The article download is still necessary, but it may be possible for the client software to automatically invoke bibliographic tools to store the found references. Another application of the Chemical Semantic Web may be as alerting services for new additions to chemical databases where users get alerts for the new additions of structures or reactions. 

U.S. Patent and Trademark Office Web Patent Databases. The Patent and Trademark Office (PTO) [72] offers free World Wide Web access, http // www.uspto.gov/main/patents.htm, to a bibliographic patent database that uses the most current patent classification system, this may not match the classification data that appears on the printed patent, and to a full-text patent database that uses the classification data that appear on the printed patent, this may not match the current classification data. The databases start with January 1, 1976, patents. The full text of a patent includes all bibliographical data (e.g., inventor s name, the patent s title, the assignee s name, etc.) and the abstract, full description of the invention, and the claims. All the words in the text of the patent are searchable. If the patent number is known, the patent, regardless of year, can be ordered from the PTO. Automated searching of 1971 to date patents is available at some of the Patent and Trademark Depository Libraries. Prior to 1971 searching can be done at the PTO facilities or at the Patent and Trademark Depository Libraries. Commercial patent search services are also available. 

The following bibliographic databases provide, to varying degrees, access to the full span of life-science periodical literature, including all stages of a compound s development from early brief reports to comprehensive assessments after years of clinical use. Some of the databases have established links from their article citations to the articles full text. 

Iowa Drug Information Service. A bibliographical database with access to full text, IDIS [98] provides access to the therapeutic and clinical pharmaceutic English language journal literature from 17 countries. FDA Summary Basis of Approval documents are indexed and available in full text. Updated monthly, the database contains over 450,000 records from 1966 forward with bibliographic citation, keyword indexes, and, for over 60% of citations, the author s abstract. IDIS is commercially available in microfiche, compact disc, and web formats and via DataStar, DIALOG. 

Some Internet search sites that I have found particularly useful include the National Center for Biotechnology information (NCBI) Entrez cross-database search page (http //www.ncbi. nlm.nih.gov/sites/gquery), which includes PubMed Central containing a limited number of free, full text journal articles. In addition, High Wire Press run by Stanford University also contains many free articles from established journals (http //highwire.stanford.edu/) and is able to search the PubMed database simultaneously. 

It can be difficult if not impossible to find the domain structure of a protein of interest from the primary literature. The sequence may contain many common domains, but these are usually not apparent from searches of literature. Articles defining new domains may include the protein, but only in an alignment figure, which are not searchable. Perhaps, with the advent of online access to articles, the full text including figures may become searchable. Fortunately there have been several attempts to make this hidden information available in away that can be easily searched. These resources, called domain family databases, are exemplified by Prosite, Pfam, Prints, and SMART. These databases gather information from the literature about common domains and make it searchable in a variety of ways. They usually allow a researcher to look at the domain organization of proteins in the sequence database that have been precalculated and also provide a way to search new sequences... 

PubMed was developed by the National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM) at the National Institutes of Health (NIH). The PubMed database was developed in conjunction with publishers of biomedical literature as a search tool for accessing literature citations and linking to full-text journal articles at Web sites of participating publishers. Publishers that participate in PubMed supply NLM with their citations electronically prior to or at the time of publication. 

EBSCOhost (www.EBSCO.com)—a large database of full text articles with over 6,200 journals that are indexed and 5,000 journals in full text. Topics include the arts and sciences, business, health, and newspapers. 

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