Virchow cell

Hultcrantz, R, Ericsson, J.L.E. and Hirth, T. (1984). Levels of malonedialdehyde production in rat liver following loading and unloading of iron. Virchows Arch. [Cell Pathol.] 45, 139-146. 

Rudolf Virchow (1821- 1902) proceeded to replace tissues with cells as the dominant materialist monads of life and disease. According to his cell doctrine, all cells, and hence all life, came from cells No developed tissue can be traced back either to any large or small simple element, unless it be to a cell (quoted from Libby, 1922, p. 267). (The phrase, Omnis cellula e cellula , however, frequently attributed to Virchow, seems to have been first used as an epigraph by Francois Raspail (1794-1878) (Harris, 1999, P- 33)). 

Keenan, K. P., J. W. Combs and E. M. McDowell, Regeneration of hamster tracheal epithelium after mechanical injury, Virchows Arch. [Cell Pathol.] 41, Parts I, II, and II 193-252 (1982). 

In 1846, Virchow first recognized the existence in the CNS of a fragile, non-nervous, interstitial component made up of stellate or spindle-shaped cells, morphologically distinct from neurons, which he named neuroglia, or... 

Altmannsberger M, Dirk T, Droese M, Weber K, Osborn M (1986) Keratin polypeptide distribu tion in benign and malignant breast tumors subdivision of ductal carcinomas using monoclo nal antibodies. Virchows Arch B Cell Pathol Incl Mol Pathol 51(3) 265 275 Assefnia S, Jones LP, Torre KM, Furth PA (2006) Expression of p63 in a mouse model of Brcal mutation related breast cancer. Poster presented at the Annual Meeting of the American Association for Cancer Research, Washington, DC (Meeting Abstracts)... 

Moll R, Franke WW, Vole Platzer B, Krepler R (1982b) Different keratin polypeptides in epider mis and other epithelia of human skin a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas. J Cell Biol 95(1) 285 295 Moll R, Krepler R, Franke WW (1983) Complex cytokeratin polypeptide patterns observed in certain human carcinomas. Differentiation 23(3) 256 269 Moll R, Dhouailly D, Sun TT (1989) Expression of keratin 5 as a distinctive feature of epithelial and biphasic mesotheliomas. An immunohistochemical study using monoclonal antibody AE14. Virchows Arch B Cell Pathol Incl Mol Pathol 58(2) 129 145 Moll R, Schiller DL, Franke WW (1990) Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns. J Cell Biol 111(2) 567 580... 

Watanabe R, Tanaka Y. 1982. Age-related alterations in the size of human hepatocytes A study of mononuclear and binucleate cells. Virchows Arch 39 9-20. 

Virchow, who was largely responsible for the acceptance of the cell theory, developed microscopy of cells from normal and diseased tissues as a major tool (histopathology) in the clinical armory. He believed the vital functions of the cell, growth, maintenance, and multiplication were discharged by its nucleus the specialised, distinguishing functions were made possible by the extranuclear constituents. In a Sunday evening lecture in Edinburgh in 1868, On the Physical Basis of Life , Thomas Huxley described cells as protoplasmic masses usually... 

Walker C, Virchow J-C, Bruijnzeel PLB, Blaser K T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma. J Immunol 1991 146 1829-1835. 

Bratke K, Lommatzsch M, Julius P, Kuepper M, Kleine HD, Luttmann W, Christian Virchow J Dendritic cell subsets in human bronchoalveolar lavage fluid after segmental allergen challenge. Thorax 2007 62 168-175. 

Idzko M, Hammad H, van Nimwegen M, Kool M, Willart MA, Muskens F, Hoogsteden HC, Luttmann W, Ferrari D, Di Virgiho F, Virchow JC Jr, Lambrecht BN Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells. Nat Med 2007 13 913-919. 

Takahashi, K., Isobe, T., Ohtsuki, Y., Akagi, T., Sonobe, H., and Okuyama, T. (1984) Immunohistochemical stndy on the distribution of alpha and beta subunits of S-100 protein in human neoplasm and normal tissues. Virchow Arch. B Cell. Pathol. 45, 385-396. 

McDowell, E. M., Keenan, K. P., and Huang, M. (1984a). Effects of vitamin A-deprivation on hamster tracheal epithelium. A quantitative morphologic study. Virchows Arch. B Cell Pathol. Inch Mol. Pathol. 45,197-219. 

Kamiyama, R. (1982). Fibrous long spacing-like fibers in the bone marrow of myeloproliferative disorder. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. 39, 285-291. 

Biesterfeld, S., Striepecke, E., and Bocking, A. 1995. Single-cell-based quantification of the proliferation fraction by image analysis. Virchows Arch. 427 339-341. 

Chen IL, Lee CY (1970) Ultrastructural changes in the motor nerve terminals caused by beta-bungarotoxin. Virchows Arch B Cell Pathol 6 318-25... 

M. L. Hautekeete and A. Geerts, The hepatic stellate (Ito) cell Its role in human liver disease, Virchows Arch. 430 195-207 (1997). 

G. Ramadori, The stellate cell (Ito-cell, fat-storing cell, lipocyte, perisinusoidal cell) of the liver. New insights into pathophysiology of an inMguing cell, Virchows Arch. [B] 67 147-158 (1991). 

L20. Luttmann, W., Matthiesen, T., Matthys, H., and Virchow, J. C., Synergistic effects of interleukin-4 or interleukin-13 and tumor necrosis factor-a on eosinophil activation in vitro. Am. J. Respir. Cell Mol. Biol. 20, 474-480 (1999). 

M19. Miiller-Hocker, J., Johannes, A., Droste, M., Kadenbach, B., Pongratz, D., and Hubner, G., Fatal mitochondrial myopathy in Kearns-Sayre syndrome with deficiency of cytochrome oxidase in the cardiac and skeletal muscle An enzyme-histochemical ultra-immunocytochemical fine structural study in longterm frozen autopsy tissue. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. 52, 353-367 (1986). 

In 1852 Robert Remak explicitely rejected the free-formation idea and concluded that Cells always come from the division of other cells. In 1855 Rudolf Virchow reached the same conclusion by studying a great number of normal and pathological adult tissues, and condensed it with the motto omnis cellula e cellula . The final version of the cell theory is therefore the combination of Schleiden and Schwann s first theory with the conclusion of Remak and Virchow All living creatures are made of cells and of cell products, and cells are always generated by the division of other cells. ... 

Ghadially EN, Lock CJL, Lalonde JMA, Ghadially R. Platinosomes produced in synovial membrane by platinum coordination complexes. Virchows Arch., B, Cell Pathol. 1981 35 123-131. Beretta GL, Righetti SC, Lombardi L, Zunino F, Perego P. Electron microscopy analysis of early localization of cisplatin in ovarian carcinoma cells. Ultrastruct. Pathol. 2002 26 331-334. Ruben GC. Ultrathin (Inm) vertically shadowed platinum-carbon replicas for imaging individual molecules in freeze-etched biological DNA and material science metal and plastic specimens. J. Electron. Microsc. Tech. 1989 13 335-354. 

For the second route, leukocytes reach the CNS from blood to subarachnoid space. In this pathway, leukocytes travel from the internal carotid artery, across postcapillary venules at the pial surface of the brain into the subarachnoid space and the Virchow-Robin perivascular spaces. There, they might encounter cells of the monocyte/myeloid lineage that are competent for antigen presentation. The perivascular regions, wkere there is direct communication with the CSF compartment, are considered probable sites of lymphocyte-APC interaction and therefore, of immune surveillance of CNS. This pathway is also dependent on P-selecdn. 

Shimizu A, Yamanaka N Apoptosis and cell desquamation in repair process of ischemic tubular necrosis. Virchows Arch.B Cell Pathol.lncl.Mol.Pathol. 64 171 -180,1993... 

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