Dendritic cell subsets

Pulendran, B., Linggappa, J., Kennedy, M.K., Smith, J., Teepe, M., Rudensky, A., Maliszewski, C.R. and Maraskovsky, E. (1997) Developmental pathways of dendritic cells in vivo distinct function, phenotype, and localisation of dendritic cell subsets in FLT3 ligand-treated mice. Journal of Immunology 159,... 

De Heer HJ. Hammad H. Kool M. Lambrecht BN Dendritic cell subsets and immune regulation in the lung. Semin Immunol 2005 17 295-303. 

Xanthou G. Alissafi T, Semitekolou M, Simoes DC. Economidou E. Gaga M, Lambrecht BN. Lloyd CM. Panoutsakopoulou V Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets. Nat Med 2007 13 570-578. 

Bratke K, Lommatzsch M, Julius P, Kuepper M, Kleine HD, Luttmann W, Christian Virchow J Dendritic cell subsets in human bronchoalveolar lavage fluid after segmental allergen challenge. Thorax 2007 62 168-175. 

Iwasaki A, Kelsall B Location of distinct Peyer s patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3a, MIP-3 3, and secondary lymphoid organ chemokines. J Exp Med 2000 191 1381-1393. 

CCR7 Mature dendritic cells, subset T- and B-cells MIP-3P/ELC (CCL19), SLC/6Ckine/exodus 2 (CCUl)... 

Notably, 90% of AD patients show lesions colonized with Staphylococcus aureus and exhibit a significant reduction of colonization in nonlesional skin [17-19], Various products of S. aureus such as peptidoglycan and superantigens are known to induce the expression of proinflammatory cytokines in monocytes and dendritic cell subsets [20]. 

Pulendran B, Smith JL, Caspary G, Brasel K, Pettit D, Maraskovsky E, Maliszewski CR Distinct dendritic cell subsets differentially regulate the class of immune response in vivo. Proc Natl Acad Sci USA 1999 96 1036-1041. 

Maldonado-Lopez R, Moser M Dendritic cell subsets and the regulation of Thl/Th2 responses. Semin Iimnunol 2001 13 275-282. 

Pulendran, B., Smith, JU., Caspary, G., Brasel, K., Pettit, D., Mataskovsky, E., and Maliszewski, C Jl. (1999) Distinct Dendritic Cell Subsets Differentially Regulate the Class of Immune Response In Vivo, Proc. Natl. Acad. Sci. USA 96,1036 1041. 

Although Thl/Th2 skewing by the dendritic cell subsets seems to guide the immune response toward cellular or humoral mechanisms, the cytotoxic effects of CD8 T lymphocytes appears less affected. Both CDS a -dendritic cells and CDS a "-dendritic cells can induce cytotoxic T-lymphocyte activity and proliferation (66,67). 

Turville SG, Cameron PU, Handley A et al. Diversity of receptors binding HIV on dendritic cell subsets. Nat Immunol 2002 3 975-983. 

Villadangos, J.A., Schnorrer, P. Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo. Nature Reviews Immunology 7, 543-555 (2007)... 

Kadowaki N. Ho S. Antonenko S. Malefyt RW, Kastelein RA. Bazan F. Liu YJ Subsets of human dendritic cell precursors express different toll-hke receptors and respond to different microbial antigens. J Exp Med 2001 194 863-869. 

CD lb Known to be present on thymocytes and dendritic cells CDlc Isoform c also known as non-classical MHC class I-like surface antigen present on thymocytes CD2 Defines T cells involved in antigen non-specific cell activation CD3 Also known as T cell receptor-associated surface glycoprotein on T cells CD4 Defines MHC class Il-restricted T cell subsets... 

Two Subsets of Naive Dendritic Cells with Distinct Migration and Functional Potentials... 

Dalod M, Hamilton T, Salomon R, et al. Dendritic cell responses to early murine cytomegalovirus infection subset functional specialization and differential regulation by interferon alpha/beta. J Exp Med 2003 197(7) 885-898. 

The mechanism(s) underlying this protective default are only partially understood, but it appears that this immunological rheostat is set via the activity of local dendritic cell (DC) subsets [7]. Immature DC, such as those found within the respiratory... 

To characterize IRIV-elicited immune responses in vitro, we addressed cell proliferation and cytokine expression in peripheral blood mononuclear cell (PBMC) cultures, as well as IRIV effects on dendritic cells (DC). In all experiments, PBMC were obtained from healthy donors and, if needed, further separated into different cell subsets. Finally, cells were cultured in the presence or absence of IRIV as indicated. 

Vernon P, Alio V, Riviere C, Bernard J, et al. 2007. Major subsets of human dendritic cells are efficiently transduced by self-complementary Adeno-associated vims vectors 1 and 2. J Virol. 81 5385-5394. 

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