Immunohistochemical studies

Xia M, Qin S, McNamara M, Mackay C, Hyman BT (1997) lnterleukin-8 receptor B immunore-activity in brain and neuritic plaques of Alzheimer s disease. Am J Pathol 150 1267-1274 Xia MQ, Bacskai BJ, Knowles RB, Qin SX, Hyman BT (2000) Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes in vitro ERKl/2 activation and role in Alzheimer s disease. J Neuroimmunol 108 227-235 Xia MQ, Qin SX, Wu LJ, Mackay CR, Hyman BT (1998) Immunohistochemical study of the beta-chemokine receptors CCR3 and CCR5 and their Ugands in normal and Alzheimer s disease brains. Am J Pathol 153 31-37... [Pg.190]

Immunohistochemical studies carried out in our laboratories have demonstrated the presence of xanthine oxidase in synovial endothelial cells (Stevens etal., 1991). As expected, the activity of this enzyme per unit weight of tissue is generally higher in synovia taken from RA patients due to their increased vascularity (Allen et al., 1987). In addition, it has also been shown that rheumatoid synoviocytes contain increased levels of iron-saturated ferritin (Morris et d., 1986). Xanthine oxidase (but not dehydrogenase) is able to mobilize iron from ferritin, supplying the necessary transition metal catalyst for the Haber-Weiss reaction and promoting OH formation (Biemond eta/., 1986). [Pg.100]

Injury (either physical or chemical) to the comeal endothelial cells has a marked efiect on occular function as these cells are responsible for maintaining the thickness and clarity of the cornea, yet they cannot be replaced if damaged. Immunohistochemical studies have revealed that enzymatic antioxidant defences, SOD, CAT and GSHPx, are similarly distributed in the corneal epithelium and endothelium (Rao etal., 1985 Attala et d., 1987, 1988). Other antioxidants include ascorbate, carotenoids and vitamin E (Fleath, 1962). [Pg.128]

Oka, S., Ogino, K., Hobara, T., Yoshimura, S., Okazaki, Y., Takemoto, T., Kato, N., lida, Y. and Uda, T. (1990b). An immunohistochemical study of copper, zinc-containing superoxide dismutase detected by a monocloncal antibody in gastric mucosa and gastric cancer. Histopathology 17, 231-236. [Pg.168]

Previous studies have also indicated that fenfluramine produces signs of neuronal degeneration (Harvey and McMaster 1975 Harvey and McMaster 1977 Harvey et al. 1977). Recent immunohistochemical studies also indicated that fenfluramine produced morphological damage to 5-HT terminal fields (Appel and De Souza 1988). Collectively, the neurochemical and histological data support the idea that fenfluramine is neurotoxic to 5-HT. [Pg.149]

Lidov, H.G.W., and Molliver, M.E. An immunohistochemical study of serotonin neuron development in the rat Ascending pathways and terminals fields. Brain Res Bull 8 389-430, 1982. [Pg.300]

Takahashi S., Iwanaga T Takahashi Y., Nakano Y., et al. (1984). Neuron-specific enolase, neurofilament protein and S-100 protein protein in the olfactory mucosa of human fetuses an immunohistochemical study. Cell Tiss Res 238, 231-234. [Pg.251]

Miller RH, David S, Patel R, Abney ER, Raff MC 1985 A quantitative immunohistochemical study of macroglial cell development in the rat optic nerve in vivo evidence for two distinct astrocyte lineages. Dev Biol 111 35-41... [Pg.106]

Jones, B. E. Beaudet, A. (1987). Distribution of acetylcholine and catecholamine neurons in the cat brainstem a choline acetyltransferase and tyrosine hydroxylase immunohistochemical study. J. Comp. Neurol. 261, 15-32. [Pg.51]

Shiromani, P. J., Armstrong, D. M. Gillin, J. C. (1988). Chohnergic neurons from the dorsolateral pons project to the medial pons a WGA-HRP and choline acetyltransferase immunohistochemical study. Neurosci Lett. 95, 19-23. [Pg.142]

Lavoie B., Parent A. (1990). Immunohistochemical study of the serotoninergic innervation of the basal ganglia in the squirrel monkey. J. Comp. Neurol. 299, 1-16. [Pg.215]

Immunohistochemical studies have shown that 8 receptors are closely associated with descending serotoninergic neurons [49]. 8 receptor-positive fibers were also found apposed to tyrosine hydroxylase-positive neurons in the locus coeru-... [Pg.465]

The maintenance of fi receptor/adenylyl cyclase coupling indicates that chronic morphine treatment does not downregulate the fi receptor to the extent of abolishing function. This has been confirmed by immunohistochemical studies which have shown that morphine treatment does not internalize or downregulate the cloned fi receptor [80, 89]. [Pg.472]

Yasuda K, Yamashita S, Aiso S, et al. Immunohistochemical study of gamma-glutamyl transpeptidase with monocloncal antibodies. I. Preparation and characterization of monoclonal antibodies to gamma-glutamyl transpeptidase. Acta Histochem. Cytochem. 1986 19 589-592. [Pg.282]

Waldvogel, H. J., Fritschy, J. M Mohler, H., and Faull, R. L. M. (1998) GABAa receptors in the primate basal ganglia an autoradiographic and a light and electron microscopic immunohistochemical study of the ai and p2 3 subunits in the baboon brain../. Comp. Neurol. 397,297-325. [Pg.106]

Fritschy, J. M., Paysan, J., Enna, A., and Mohler, H. (1994) Switch in the expression of rat GABAA-receptor subtypes during postnatal development an immunohistochemical study. J. Neurosci. 14,5302-5324. [Pg.110]

Demirkesen C, Hoede N, Moll R (1995) Epithelial markers and differentiation in adnexal neoplasms of the skin an immunohistochemical study including individual cytokeratins. JCutan Pathol 22(6) 518 535... [Pg.126]

Moll R, Franke WW, Vole Platzer B, Krepler R (1982b) Different keratin polypeptides in epider mis and other epithelia of human skin a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas. J Cell Biol 95(1) 285 295 Moll R, Krepler R, Franke WW (1983) Complex cytokeratin polypeptide patterns observed in certain human carcinomas. Differentiation 23(3) 256 269 Moll R, Dhouailly D, Sun TT (1989) Expression of keratin 5 as a distinctive feature of epithelial and biphasic mesotheliomas. An immunohistochemical study using monoclonal antibody AE14. Virchows Arch B Cell Pathol Incl Mol Pathol 58(2) 129 145 Moll R, Schiller DL, Franke WW (1990) Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns. J Cell Biol 111(2) 567 580... [Pg.128]

Immunohistochemical study ND not determined GLUT1 facilitative glucose transporter MCT1 monocarboxylate transporter CRT creatine transporter LAT1 L-type amino acid transporter TAUT taurine transporter ENT equilibrative nucleoside transporter Oatp organic anion-transporting polypeptide PAH p-aminohippuric acid RUI retinal uptake index TR-iBRB rat retinal capillary endothelial cells. [Pg.333]

Shinoda K, Yagi H, Fujita H, Osawa Y, Shiotani Y. 1989. Screening ofaromatase-containing neurons in ratforebrain an immunohistochemical study with antibody against human placental antigen X-P2 (hPAX-P2). J Comp Neurol 290 502-515. [Pg.89]

Traditionally, immunohistochemical studies have been performed with antibodies of polyclonal origin. Antibodies are said to be polyclonal when they are collected from different clones of cells, after a significant immune response. Specifically, the presence of an antigen causes lymphocytes in an exposed area to... [Pg.195]

Teaktong T, Graham AJ, Johnson M, Court JA, Perry EK (2004) Selective changes in nicotinic acetylcholine receptor subtypes related to tobacco smoking an immunohistochemical study. Neuropathol Appl Neurobiol 30 243-254... [Pg.205]

Terada, M., Iwanaga, T., Takahasi-Iwanaga, H., Adachi, I., Arakawa, M., and Fujita, T. (1992) Calcitonin gene-related peptide (CGRP)-immunoreactive nerves in the tracheal epithelium of rats an immunohistochemical study by means of whole-mount preparations. Arc/t. Histol. Cytol. 55, 219-233. [Pg.139]

Bansal, G., Martenson, R. E., Leveille, P., and Campagnoni, A. T. (1987) Characterization of a novel monoclonal anti-myelin basic protein antibody use in immunoblotting and immunohistochemical studies. J. Neuroimmunol. 15, 279-294. [Pg.436]

Bohlhalter S, Weinmann O, Mdhler H, Fritschy JM (1996) Laminar compartmentalization of GABAA-receptor subtypes in the spinal cord an immunohistochemical study. J Nemosci... [Pg.240]

Fray AE, luce PG, Banner SJ, et al (1998) The expression of the glial glutamate transporter protein EAAT2 in motor neiuon disease an immunohistochemical study. Eiu" J Neurosci 10 2481-2489... [Pg.290]

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