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Ursolic acids

Uronic acids 154,199, 322,426 Uroporphyrin 102 Ursolic acid 59, 71 UV lamps 13,14,16,137 with camera holder 13,17,136 UV absorber in plastics 281... [Pg.241]

Oleanolic acid, ursolic acid, betuhc acid... [Pg.533]

Other sorts of NO inhibitors are triterpenes, such as ursolic acid and 2-a-hydroxy ursolic acid and 2-a-hydroxy ursolic acid from Prunella vulgaris L., inhibit the production of NO by murine leukaemic monocyte macrophage cells, RAW 264.7, cultured in vitro. The IC50 values were 17 xM for ursolic acid and 27 jxM for 2-a-hydroxy ursolic (51). [Pg.52]

Figure 5.1 Structures of the pure triterpenes studied by GALDI MS hydroxydammarenone (20 hydroxydammar 24 en 3 one) 1, oleanolic acid (3 hydroxyolean 12 en 28 oic acid) 2, oleanonic acid (3 oxoolean 12 en 28 oic acid) 3, 18(3 glycyrrhetinic acid ((3(3,18(3,20(3) 3 hydroxy 11 oxoolean 12 en 29 oic acid) 4, uvaol (urs 12 en 3,28 diol) 5, ursolic acid (3 hydroxyurs 12 en 28 oic acid) 6, and ursonic acid (3 oxours 12 en 28 oic acid) 7... Figure 5.1 Structures of the pure triterpenes studied by GALDI MS hydroxydammarenone (20 hydroxydammar 24 en 3 one) 1, oleanolic acid (3 hydroxyolean 12 en 28 oic acid) 2, oleanonic acid (3 oxoolean 12 en 28 oic acid) 3, 18(3 glycyrrhetinic acid ((3(3,18(3,20(3) 3 hydroxy 11 oxoolean 12 en 29 oic acid) 4, uvaol (urs 12 en 3,28 diol) 5, ursolic acid (3 hydroxyurs 12 en 28 oic acid) 6, and ursonic acid (3 oxours 12 en 28 oic acid) 7...
Liu J. (1995) Pharmacology of oleanoUc acid and ursolic acid. J Ethno-pharmacol 49 57-68. [Pg.172]

He shou wu, a herhal formulation has been used for the treatment of skin tumors. For topical use, the powder is mixed with sesame oil and applied. He shou wu has been used for centuries to help maintain the youthful color of one s hair and also to help diminish hair loss. Holy basil contains ursolic acid (Fig. 7) — one of the cosmetic industry s latest favorites because not only does it quickly heal the skin, it also improves elasticity and removes wrinkles. It also shows benefits for preventing skin cancer. A poultice made from the herh is used topically for its antifungal and antibacterial actions. ... [Pg.511]

Shishodia S, Majnmdar S, Banerjee S, Aggarwal BB. (2003) Ursolic acid inhibits nnclear factor-kappa B activation indnced by carcinogenic agents throngh snppression of Ikappa Balpha kinase and p65 phosphorylation Correlation with down-regnlation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin Dl. Cancer Res 63 4375 383. [Pg.517]

XIV, R = CH3 and C2H5, respectively, Fig. 10b), whereas the sediment contains additional friedelin, i-friedelanol and ursolic acid. Furthermore, the friedelin photoproducts, i.e. dihydroputranjivic acid (3,4-r c<7-friedelan-3-oic acid, XV) and 4a- and 4P-3-norfriedelane (XVI) are dominant sedimentary components. Thus, characterizing photoproducts from terpenoids may provide additional biomarker tracer compounds for environmental studies. [Pg.102]

The triterpene ursolic acid (66) was identified as the active component of Origanum majorana Another triterpene which has been... [Pg.407]

Chung YK, Heo HJ, Kim EK, Inhibitory effect of ursolic acid purified from Origanum majorana L. on the acetylcholinesterase, Mol Cells 11 137—143, 2001. [Pg.424]

Moved] Cranberry fruit of Early Black cultivar was fractionated chromatographically and fractions were analyzed for flavonoid content. The effects of the flavonoid fractions and ursolic acid, an abundant triterpenoid in cranberry peel, were assessed in two models of colon cancer and one model of breast cancer. Clonogenic soft agar assays were used to determine the effect of these compounds on tumor colony formation in HCT-116, HT-29 and MCF-7 cells. MTT and trypan blue assays were performed to assess their ability to inhibit tumor cell proliferation. TUNEL assays were performed to assess apop-totic response to the cranberry compounds. The proanthocyanidins inhibited tumor colony formation in HCT-116 and HT-29 cells in a dose-dependent manner, with greater effect on the HCT-116 cell line. Ursolic acid strongly inhibited tumor colony formation in both colon cell lines. These compounds also decreased proliferation in all three tumor cell lines with the HCT-116 cell line most strongly affected. (150 words)... [Pg.285]

Liberty, A. M. Hart, P. E. Neto, G. G. Ursolic Acid and Proanthocyanidins from Cranberry (Vaccinium macrocarpon) Inhibit Colony Formation and Proliferation in HCT-116 and HT-29 Colon and MCF-7 Breast Tumor Cells. Proceedings of the 233rd American Chemical Society National Meeting, Chicago, IL, March 25-29, 2007. [Pg.675]

Kams, and P. W. Geno. Isolation and CA097 characterization of ursolic acid from Coffea arabica L. (coffee) leaves. [Pg.188]

Mamedova, M. E., and S. M. Aslanov. Contents of ursolic acid in flowers of Olea europaea L. (Azerbaijan). Rast Resur 1992 28(3) 79-81. [Pg.390]

Mipando. Cardiotonic and antidys-rhythmic effects of oleanolic and ursolic acids, methyl maslinate and uvanol. Phytomedicine 2004 11(2-3) 121-129. [Pg.398]

Antileukemic activity. Aucubin, in combination with caffeic acid, chlorogenic acid, ferulic acid, p-coumaric acid, and vanillic acid, exhibited weak antileukemic activity (inhibitory concentration [ICJjo 26-56 pg/ mL, international system of units 2-11) on human leukemia and lymphoma cell lines. Water-insoluble compounds, such as triterpenoids (oleanolic acid and ursolic acid), monotepene (linalool), and flavonoid (luteolin) produced strong activity " . Anti-nematodal activity. Water extract of the dried seed, at various concentrations, was active on Meloidogyne incognita Anti-yeast activity. Ethanol (80%) extract of the dried entire plant, on agar plate at a concentration of 1 mg/mL, was inactive on Candida albicans K... [Pg.423]

The betulinic acid level in the E. florida leaves increased significantly in the May, June, Jully (autumn - winter) and, September, October and November (winter) which was mainly due to the accumulation of this compound in vegetal tissue. Some authors related with the pentacyclic triterpenes, just as betulinic, acid ursolic, acid, p-amyrine and lupeol, are supposed to be toxic to insects, due to their ability to inhibit acyl chain packing in the lipid bilayers of the insect membranes [Rodriguez et al, 1997 Prades et al., 2011]. [Pg.189]

Huang MT, Ho CT, Wang ZY, et al. Inhibition of skin tumorigenesis by rosemary and its constituents carnosal and ursolic acid. Cancer Res 1994 54 701-708. [Pg.44]

Chimaphila umbellata (L.) W. Barton Mei Li Cao (whole plant) Arbutin, ursolic acid, homoarbutin, chimaphilin, isohomoarbutin, hyperin, avicularin, kaempferol, renifolin, beta-amyrin, ericolin, andromedotoxin, chinic acid.48 Diuretic, relieve stomach, tooth and after-birth pains, antifungal. [Pg.51]

Clinopodium chinense (Benth.) C. gracile (Benth.) O. Kuntze. C. polycephalum (Benth.) C. umbrosum (Bleb.) C. Koch. Duan Xue Liu Guang Feng Lun Cai Feng Lun Cai (whole plant) Dydimin, hesperidin, siosakuranetin, apigenin, ursolic acid.48 Hemostatic, stimulate uterine contractions, antibacterial. [Pg.56]

Cynomorium coccineum L. C. songarium L. Su Yang (Juniper) (stem) Anthocyanin, beta-sitosterol, palmitic acid, ursolic acid, daucosterol, catechin, naringenin-4 -0-pyranogluoside, succinic acid.53-215 Improve immunity, stimulate endocrine system, aphrodisiac, spermatopoietic. [Pg.66]

Ilex chinensis Sims Shi Ji Qing (Wintergreen holly) (leaf) Protocatechuic acid, protocatechuic aldehyde, ursolic acid, tannic acid.33 Treat angina pectoris, thrombophlebitis, extremity ulceration. [Pg.93]

Ilex pubescens Hook Am. Mao Dong Qing (Holly) (leaf, root) Flavone, ursolic acid, scopoletin, 3,4-dihydroxy acetophenone, hydroquinone, vomifliol.33 Treat angina pectoris, acute myocardial infarction, central angiospastic retinitis, cerebral thrombosis, thrombophlebitis. [Pg.93]

Ligustrum lucidum Mill. L. japonicum Thunb. Nu Zhen Zi (Wax tree) (fruit) Nuzhenide, oleanolic acid, ursolic acid.33-445 Increase leukocyte count, a cardiac tonic, diuretic, treat urological tumors. [Pg.99]

Melaleuca leucadendra L. Bai Qian Ceng (Cajeput) (leaf) Cajuputol, cineole, eucalyptol, lignin, melaleucin, pinene, terpinol, 1-limonene, dipentene, nerolidiol, sesquiterpenes, azulene, sesquiterpene alcohols, valeraldehyde, benzaldehyde, betulinic acid, oleanolic acid, ursolic acid, quercimeritrin, isoquercitrin, gallic acid.50 Treat dropsy, oil is for gout, inhaled to treat colds, rhinitis, embrocation against rheumatism. It is an anodyne, antispetic. [Pg.110]

Nerium indicum Mill. Jia Zhu Tao (Indian oleander) (leaf, stem, flower, root) Oleandrin (toxic), oleandrose, neriodorin, nerioderin, karabin, scopoletin, scopoline, neriodin, ursolic acid, adynerin 33>45° Treats psychosis, congestive heart failure, analgesic, emmenagogue. [Pg.116]

Oldenlandia chrysotricha L. O. corymbosa L. Shi Da Chuan Shui Xian Cao (leaf) Biflorine, biflorone, gamma-sitosterol, stigmasterol, ursolic acid, oleanolic acid.50 Ferbrifuge, for hepatomegaly, lymphadenitis, neophasia, splenomegaly. [Pg.117]

Oldenlandia diffusa L. Bai Hua Shi Shi Cao (aerial part) Asperuloside, palderoside, desacetylasperuloside, beta-sitosterol, stigmasterol, ursolic acid, oldenlandoside.33 Treats mahgnant tumors, hepatomas, hepatomegaly, cancer of the cervix, esophagus, stimulates reticuloendothelial system. [Pg.117]

Plantago asiatica L. depressa Willd. exaltata Horn. P. loureiri Roem. et Schult. P. major L. P. major L. var. asiatica DC Che Chen Zi (Plantain) (seed) d-xylose, 1-arabinose, d-galacturonic acid, 1-rhamnose, plantasan, plantenolic acid, plantagin, homoplantagin, aucubin, ursolic acid, hentriacontane.48-510 Diuretic, expectorant, intestinal infection, diarrhea caused by bacteria. [Pg.128]

Prunella vulgaris L. Xia Ku Chao (Heal-all) (leaf) Caffeic acid, d-camphor, cyanidin, delphinidin, d-fenchone, hyperoside, oleanolic acid, rutin, ursolic acid.48 450 Antibacterial, antipyretic, cardiac tonic, diuretic, anticancer. [Pg.134]

Punica granatum L. Shi Liu Pi (Pomegranate) (pericarp, root bark) Pelletierine, isopelletierine, methylisopelletierine, methyl-pelletierine, pseudopelletierine, gallotannic acid, sitosterol, ursolic acid, maslinic acid, elegic and gallic acid.33-450 This herb is toxic. Purges intestinal parasites. [Pg.136]

Rubus coreanus Miq. R. crataegifolius Bunge. R. matsumuranus Levelle Vaniot R. matsumuranus Levelle Vaniot var. concolor (Kom.) Kitag. R. saxatilis L. Fu Pen Zi (Briar rose) (fruit, root) Beta-sitosterol, stigmasterol, campesterol, cholestanol, ursolic acid, flavonoids.48 Diuretic, aphrodisiac, level infection, j oint infection caused by arthritis. [Pg.142]

Solarium incanum L. Huang Shui Jia (root) Beta-sitosterol, D-glucose, ursolic acid, alkaloids, solasodine, solamargine.55 Treat liver inflammation, lymphatic gland, a detoxicant. [Pg.152]


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