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Oleanolic acids

Oleanolic acid, ursolic acrd, betulic acid... [Pg.59]

Matsuda H, Dai Y, Ido Y, et al. Studies on Kochiae fiructus. V. Antipruritic effects of oleanolic acid glycosides and the structure-requirement. Biol Pharm Bull 1998 21 1231-1233. [Pg.68]

Figure 3.1 Mass spectra of (a) a amyrine and (b) oleanolic acid obtained by DE MS... Figure 3.1 Mass spectra of (a) a amyrine and (b) oleanolic acid obtained by DE MS...
Figure 5.1 Structures of the pure triterpenes studied by GALDI MS hydroxydammarenone (20 hydroxydammar 24 en 3 one) 1, oleanolic acid (3 hydroxyolean 12 en 28 oic acid) 2, oleanonic acid (3 oxoolean 12 en 28 oic acid) 3, 18(3 glycyrrhetinic acid ((3(3,18(3,20(3) 3 hydroxy 11 oxoolean 12 en 29 oic acid) 4, uvaol (urs 12 en 3,28 diol) 5, ursolic acid (3 hydroxyurs 12 en 28 oic acid) 6, and ursonic acid (3 oxours 12 en 28 oic acid) 7... Figure 5.1 Structures of the pure triterpenes studied by GALDI MS hydroxydammarenone (20 hydroxydammar 24 en 3 one) 1, oleanolic acid (3 hydroxyolean 12 en 28 oic acid) 2, oleanonic acid (3 oxoolean 12 en 28 oic acid) 3, 18(3 glycyrrhetinic acid ((3(3,18(3,20(3) 3 hydroxy 11 oxoolean 12 en 29 oic acid) 4, uvaol (urs 12 en 3,28 diol) 5, ursolic acid (3 hydroxyurs 12 en 28 oic acid) 6, and ursonic acid (3 oxours 12 en 28 oic acid) 7...
Figure 5.2 GALDI mass spectra of (a) fresh hydroxydammarenone (1, sodium adduct [M+Na]+ at m/z 465) and (b) an equimolar mixture of hydroxydammarenone (1 H, m/z 465), uvaol (5 U, m/z 465), oleanonic acid (3 On, m/z 477), oleanolic acid (2 Ol, m/z 479), andglycyrrhetinic acid (4 G, m/z 493) [39]. In (a), a small amount of (M+16) is visible at m/z 481 in the unaged sample. Signals marked with crosses at m/z 413, 469, 483, and 507are contaminants in the spectrometer... Figure 5.2 GALDI mass spectra of (a) fresh hydroxydammarenone (1, sodium adduct [M+Na]+ at m/z 465) and (b) an equimolar mixture of hydroxydammarenone (1 H, m/z 465), uvaol (5 U, m/z 465), oleanonic acid (3 On, m/z 477), oleanolic acid (2 Ol, m/z 479), andglycyrrhetinic acid (4 G, m/z 493) [39]. In (a), a small amount of (M+16) is visible at m/z 481 in the unaged sample. Signals marked with crosses at m/z 413, 469, 483, and 507are contaminants in the spectrometer...
Oleanolic acid, 3 epi masticadienolic acid, 3 epi isomasticadienolic acid C30H48O3... [Pg.141]

FIGURE 1.7 Possible biosynthetic route for ginsenosides of the oleanolic acid type from squalene oxide. [Pg.44]

Oleanolic acid (109) Triterpenoid RTA-402 Oncology Inhibits IkB alpha kinase Phase I/II Reata 693, 694... [Pg.68]

Antidysrrhythmic activity. Oleanolic acid and uvaol, isolated from the leaves of Oka europaea ssp. africana, administered at a dose of 40 mg/kg, were active on ischemia and reperfusion arrhytmias° . [Pg.382]

Kubo, I., and A. Matsumoto. Secreted oleanolic acid on the cuticle Olea... [Pg.391]

Antileukemic activity. Aucubin, in combination with caffeic acid, chlorogenic acid, ferulic acid, p-coumaric acid, and vanillic acid, exhibited weak antileukemic activity (inhibitory concentration [ICJjo 26-56 pg/ mL, international system of units 2-11) on human leukemia and lymphoma cell lines. Water-insoluble compounds, such as triterpenoids (oleanolic acid and ursolic acid), monotepene (linalool), and flavonoid (luteolin) produced strong activity " . Anti-nematodal activity. Water extract of the dried seed, at various concentrations, was active on Meloidogyne incognita Anti-yeast activity. Ethanol (80%) extract of the dried entire plant, on agar plate at a concentration of 1 mg/mL, was inactive on Candida albicans K... [Pg.423]

Anemone raddeana Regel A. rivularis Buch-Hamilton ex DC A. rivularis Buch-Hamilton ex DC var. flore-minore Maxim. A. vitifolia (Buch. Ham.) Nakai Yin Lian Hua, Liang Tao Jian Cao Yu Mei Ye Mian Hua (Anemone) (rhizome) Raddeanin A, hederasaponin B, raddanoside, ranuneulin, oleanolic acid.33-48 Antitumor, anti-inflammatory, antirheumatic arthritis. [Pg.28]

Aralia chinensis L. A. cordata Thunb. var. continentalis (Kitag.) Y. C. Chu A. elata (Miq.) Seem. A. elata (Miq.) Seem. F. subinermis Y. C. Chu Jia Mu, Du Huo (Aralia) (root) Diterpenoids such as (-) pimaradene, (-) kaurene derivatives, l-pimara-8, 15-dien-19-oic acid, aralosides, araligenin, oleanolic acid, beta-taralin, alpha-taralin.20 48 50 Carminative, for arthralgia, gastroenteritis, headache, diuretic, antidiabetic, antiseptic. [Pg.31]

Aristolochia contorta Bunge. A. kaempferi Willd. A. longa Thunb. A. recurvilabra Hance Ma Dou Ling (stem) Aristolochic acid A, aristolochic acid D, aristoloside, magnoflorine, oleanolic acid, beta-sitosterol, hederagenin.48 This herb is toxic. Treat pulmonary disorders, antitussive, an expectorant in asthma and bronchitis. [Pg.33]

Calendula officinalis L. Jin Tsan Jiu (Marigold) (whole plant) Arnidiol, carotenes, calenduline, cerylalcohol, flavoxanthin, lycopene, oleanolic acid, inulin, rebixanthin, violaxanthin. tocopherol, salicylic acid.50 Treat bleeding gums, bleeding piles, for amenorrhea, bruises, cholera, cramps, eruption, fevers, flu. [Pg.44]

Clematis intriicata Bunge. C. mandshurica Rupr. Tie Xian Lian (Clematis) (whole plant) Clematoside A, oleanolic acid.48 Relieve arthritis pain and related infections. [Pg.55]

Codonopsis lanceolata (Sieb. et Zucc.) Trautv. Yang Lu (Bellflower) (whole plant) Apigenin, luteolin, alpha-spinasterol, stigmastenol, oleanolic acid, echinocystic acid, albigenic acid.48 Treat lung abscesses, stimulate milk flow, treat amenorrhea. [Pg.57]

Ligustrum lucidum Mill. L. japonicum Thunb. Nu Zhen Zi (Wax tree) (fruit) Nuzhenide, oleanolic acid, ursolic acid.33-445 Increase leukocyte count, a cardiac tonic, diuretic, treat urological tumors. [Pg.99]

Melaleuca leucadendra L. Bai Qian Ceng (Cajeput) (leaf) Cajuputol, cineole, eucalyptol, lignin, melaleucin, pinene, terpinol, 1-limonene, dipentene, nerolidiol, sesquiterpenes, azulene, sesquiterpene alcohols, valeraldehyde, benzaldehyde, betulinic acid, oleanolic acid, ursolic acid, quercimeritrin, isoquercitrin, gallic acid.50 Treat dropsy, oil is for gout, inhaled to treat colds, rhinitis, embrocation against rheumatism. It is an anodyne, antispetic. [Pg.110]

Oldenlandia chrysotricha L. O. corymbosa L. Shi Da Chuan Shui Xian Cao (leaf) Biflorine, biflorone, gamma-sitosterol, stigmasterol, ursolic acid, oleanolic acid.50 Ferbrifuge, for hepatomegaly, lymphadenitis, neophasia, splenomegaly. [Pg.117]

Panax ginseng C. A. Meyer P. pseudoginseng Wall. Ren Seng (Ginseng) (root) Triterpenoid, quinquenosides, ginsenosides, oleanolic acid, panaxynol, beta-elemene, spemine, putrescine, spermindine.26-53-510-511 A stimulant, tonic, expectorant. [Pg.120]

Prunella vulgaris L. Xia Ku Chao (Heal-all) (leaf) Caffeic acid, d-camphor, cyanidin, delphinidin, d-fenchone, hyperoside, oleanolic acid, rutin, ursolic acid.48 450 Antibacterial, antipyretic, cardiac tonic, diuretic, anticancer. [Pg.134]

Swertia diluta (Turcz.) Benth. et Hook. f. S. mileensis L. Qing Ye Dan (whole plant) Oleanolic acid.33 Treat acute icteric hepatitis. [Pg.158]

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