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Liver inflammation

Canarium(spp) Burseraceae Antioxidant activity, colic, hemoorrhoids,jaundice, enema, scabies, gland inflammation, liver disease, wound healing, skin dermatitis, coughs, stomachic. Several species reported to be used in premature birthing, to expel the placenta, leprosy 17, 31... [Pg.142]

An indirect measurement of the iron-binding capacity of serum transferrin, the TIBC evaluation is performed by adding an excess of iron to plasma to saturate all transferrin with iron. The excess (unbound) iron is then removed and the serum iron concentration is determined. Unlike the serum iron level, the TIBC does not fluctuate over hours or days. The finding of a low serum iron level and a high TIBC indicates IDA. The TIBC is actually a measurement of the protein serum transferrin, which can be affected by a variety of factors. Patients with infection, malignancy, inflammation, liver disease, and uremia may have a decreased TIBC and a decreased serum iron level, which is consistent with the diagnosis of ACD. Oral contraceptive use and pregnancy can increase TIBC because the serum transferrin production is increased with a variety of other proteins. [Pg.1812]

In humans, hemoglobin concentration and hematocrit provide information about iron utilization in erythropoiesis. These parameters, however, can be confounded by inflammation, pregnancy, dehydration, polycythemia, hemoglobinopathies, and by deficiencies of vitamin B12 or folic acid (Gibson 1990). Plasma ferritin reflects body iron stores, but is also confounded by inflammation, liver diseases, leukemia, Hodgkin s disease, or alcohol intake. Transferrin saturation and plasma transferrin receptor are valuable parameters to support the diagnosis of iron deficiency and ineffective erythropoiesis (Thorstensen and... [Pg.812]

Hepatic Effects. Liver effects in humans were not reported in a compilation of cases and personal reports of acute dermal exposure to chlordane (EPA 1980a). Balistreri et al. (1973) reported clinical hepatic effects consisting of jaundice, hepatomegaly and elevated serum transaminases in an infant following "prolonged" dermal exposure to liquid chlordane. Liver biopsy revealed centrilobular necrosis, fatty infiltration, and minimal inflammation. Liver function tests were normal in a 47-year-old nurseryman who handled soil sprayed with chlordane and other chemicals for 2 years (Barnes 1967) there was no estimate of exposure concentration or dose. [Pg.73]

Iron storage diseases (hemochromatosis, multiple transfusions) Acute and chronic inflammations Liver diseases... [Pg.5290]

Toxicity. Many /V-nitrosamines are toxic to animals and cells in culture (4,6—8,88). /V-Nitrosodimethy1amine [62-75-9] (NDMA) is known to be acutely toxic to the Hver in humans, and exposure can result in death (89). Liver damage, diffuse bleeding, edema, and inflammation are toxic effects observed in humans as a result of acute and subacute exposure to NDMA. These effects closely resemble those observed in animals dosed with NDMA (89,90). [Pg.109]

Chinese Liver Fluke. The adult worm of the Chinese Hver fluke Clonorchis sinensis) can grow to be 2 cm long. Worms infect the bihary tree where they cause local inflammation, diarrhea, and hepatomegaly in the acute infection. Progressive biUary obstmction and cirrhosis can occur in the more advanced disease state. The presence of 20—200 worms is common, but they may number over 20,000. Infection is the consequence of eating raw fish that contain viable parasites. Untreated worms can Hve for up to 30 years. Treatment is with pra2iquantil (1). [Pg.244]

Hepatic Hepatic means "pertaining to the liver." For example, hepatitis is inflammation of the liver. Liver disorders are sometimes marked by jaundice, a yellowish coloration to the whites of the eyes and skin. Certain chemicals are hepatotoxins (toxic to the liver), usually as a result of chronic exposure. One example is carbon tetrachloride (CCI4). [Pg.531]

One of the first prodrugs, aspirin, is cleaved to the active agent, salcylic acid, in the liver as well as various other tissues. Despite the advent of numerous newer agents for the alleviation of the pain and inflammation characteristic of inflammatory diseases, aspirin remains the most widely used drug for this 108... [Pg.108]

Hepatitis is acute or chronic inflammation of the liver, which is frequently caused by infection with hepato-tropic viruses. Several forms of viral hepatitis (A, B, C, D, E) are known, which result from infection with viruses belonging to separate virus families, differing in their genomic organization, replication strategies, morphology and modes of transmission. [Pg.582]

Insulin resistance occurs when the normal response to a given amount of insulin is reduced. Resistance of liver to the effects of insulin results in inadequate suppression of hepatic glucose production insulin resistance of skeletal muscle reduces the amount of glucose taken out of the circulation into skeletal muscle for storage and insulin resistance of adipose tissue results in impaired suppression of lipolysis and increased levels of free fatty acids. Therefore, insulin resistance is associated with a cluster of metabolic abnormalities including elevated blood glucose levels, abnormal blood lipid profile (dyslipidemia), hypertension, and increased expression of inflammatory markers (inflammation). Insulin resistance and this cluster of metabolic abnormalities is strongly associated with obesity, predominantly abdominal (visceral) obesity, and physical inactivity and increased risk for type 2 diabetes, cardiovascular and renal disease, as well as some forms of cancer. In addition to obesity, other situations in which insulin resistance occurs includes... [Pg.636]

Unphysiologically high levels of NO formed by iNOS expressed in tissues (e.g., liver, stomach, and lung) with chronic inflammation following infections of... [Pg.858]

Systemic treatment of 13-cis retinoic acid frequently leads to cheilitis and eye irritations (e.g., unspecific cornea inflammation). Also other symptoms such as headache, pruritus, alopecia, pains of joints and bone, and exostosis formation have been reported. Notably, an increase of very low density lipoproteins and triglycerides accompanied by a decrease of the high density lipoproteins has been reported in 10-20% of treated patients. Transiently, liver function markers can increase during oral retinoid therapy. Etretinate causes the side effects of 13-cis retinoid acid at lower doses. In addition to this, generalized edema and centrilobulary toxic liver cell necrosis have been observed. [Pg.1077]

The principal adverse reaction associated with warfarin is bleeding, which may range from very mild to severe. Bleeding may be seen in many areas of the body, such as the bladder, bowel, stomach, uterus, and mucous membranes. Other adverse reactions are rare but may include nausea, vomiting, alopecia (loss of hair), urticaria (severe skin rash), abdominal cramping, diarrhea, rash, hepatitis (inflammation of the liver), jaundice (yellowish discoloration of the skin and mucous membranes), and blood dyscrasias (disorders). [Pg.420]

Increased accumulation of liposomes, especially small liposomes, has been reported to occur at sites of inflammation (Williams et al., 1986) and in tumors (Turner et al., 1988 Gabizon and Papahadjopoulos, 1988) (cf. Sec. VI.B). However, it is well established that endo-cytosis of liposomes by MPS cells, primarily those located in liver and spleen, accounts for most of the uptake of liposomes—and, in general, uptake of particulate matter—from the blood circulation. [Pg.283]

Infection with one or more strains of viral hepatitis often causes acute inflammation of the liver, while chronic infection with hepatitis B or C can lead to cirrhosis. Hepatitis B and C are common in intravenous drug users and can also be transmitted through sexual contact, but many cases of hepatitis C are idiopathic.5,6 Hepatitis C is a more common cause of cirrhosis than hepatitis B in the United States while hepatitis B is more common in the rest of the world.7 See Chapter 21 on viral hepatitis for a complete discussion of infectious hepatitis. [Pg.324]

Primary biliary cirrhosis is characterized by progressive inflammatory destruction of the bile ducts. Immune-mediated inflammation of intrahepatic bile ducts results in remodeling and scarring, causing retention of bile within the liver and subsequent hepatocellular damage and cirrhosis. The number of patients affected with primary biliary cirrhosis is difficult to estimate because many people are asymptomatic and incidental diagnosis during routine health care visits is common. [Pg.327]

Diagnosing viral hepatitis may be difficult because most infected individuals are asymptomatic. Because symptoms cannot identify the specific type of hepatitis, laboratory serologies must be obtained (Table 21-2). In addition, liver function tests may be obtained to assess the extent of cholestatic and hepatocellular injury. However, the definitive test to determine the amount of damage and inflammation of hepatic cells is a liver biopsy. [Pg.348]

Liver biopsy Mild inflammation and minimal fibrosis (grade 1, stage 1 disease) that is consistent with chronic hepatitis C... [Pg.350]

The incidence of liver complications associated with PN ranges from approximately 7% to 84%, and end-stage liver disease develops in as many as 15% to 40% of adult patients on long-term PN.35 Patients often develop a mild increase in liver enzymes within 1 to 2 weeks of initiating PN, but this generally resolves when PN is discontinued. Severe liver complications include hepatic steatosis (fat deposition in liver), steatohepatitis (a severe form of liver disease characterized by hepatic inflammation that may progress rapidly to liver fibrosis and cirrhosis), cholestasis, and cholelithiasis.35... [Pg.1506]

C-reactive protein A nonspecific inflammatory marker that may be elevated in osteomyelitis as well as other infections and inflammatory diseases represents a specific protein produced by the liver during times of inflammation. [Pg.1563]

Steatohepatitis A severe form of liver disease caused by fat deposition in the liver, characterized by hepatic inflammation that may rapidly progress to liver fibrosis and cirrhosis. [Pg.1577]


See other pages where Liver inflammation is mentioned: [Pg.474]    [Pg.577]    [Pg.365]    [Pg.474]    [Pg.577]    [Pg.365]    [Pg.199]    [Pg.404]    [Pg.48]    [Pg.49]    [Pg.50]    [Pg.167]    [Pg.386]    [Pg.148]    [Pg.410]    [Pg.456]    [Pg.744]    [Pg.888]    [Pg.939]    [Pg.943]    [Pg.411]    [Pg.85]    [Pg.151]    [Pg.88]    [Pg.89]    [Pg.115]    [Pg.284]    [Pg.903]    [Pg.1008]   
See also in sourсe #XX -- [ Pg.89 , Pg.93 , Pg.94 , Pg.96 , Pg.323 ]

See also in sourсe #XX -- [ Pg.404 ]




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