2’,4’-Dihydroxy acetophenone

Bellstein Handbook Reference) 4-Acetylresorclnol Acetophenone, 2, 4 -dihydroxy- AI3-00866 BRN 1282506 1-(2,4-Dihydroxyphenyl)ethan-one 2, 4 -Dihydroxyacetophenone EINECS 201-945-3 Ethanone, 1-(2,4-dihydroxyphenyl)- NSC 10883 Res-acetophenone Resoacetophenone Resorcinol, 4-acetyl-. Reagent specific tor iron. Solid mp = 146° d = 1.1800 insoluble in H2O, soluble in EtOH, TFA, C5H5N, AcOH, less soluble in EtzO, CeHfi. 

Me ether 2,4-Dihydroxy-6-methoxy-3,5-bis 3-methyl-2-butenyl)acetophenone. 2,4-Dihydroxy-6-methoxy-3,5-diprenylacetophenone C19H26O4 M 318.412 Constit. of Acronychia pedunculata. Yellow oil. 

Ethers of benzenepentol have been obtained by Dakin oxidation of the appropriately substituted acetophenone. Thus, the oxidation of 2-hydroxy-3,4,6-ttimethoxyacetophenone and 2-hydroxy-3,4,5-ttimethoxyacetophenone with hydrogen peroxide ia the presence of alkali gives l,2-dihydroxy-3,4,6-ttimethoxybenzene and l,2-dihydroxy-3,4,5-ttimethoxybenzene, respectively further methylation of these ethers yields the pentamethyl ether of benzenepentol (mp 58—59 degC) (253). The one-step aromatization of myoinositol to produce esters of pentahydroxybenzene is achieved by treatment with carboxylic acid anhydrides ia DMSO and ia the presence of pyridine (254) (see Vitamins). 6-Alkyl- or... 

Tetraazafulvalenes bearing two pyrazole subunits could be prepared by an original way. Tlius, treatment of benzylidene acetophenone with iso-pentylnitrite leads to an A, A -dihydroxy-bipyrazolyl-A, A -oxide, which in turn can be oxidized to TAF of type 100 (72CC961, 79JOC3211). Another type of oxidative dimerization was observed by the reaction of the electron-rich l-methyl-2,4-bis(dimethylamino)imidazole with silver salts (83TL3563). A bis-cation was isolated in 30% yield in the presence of sodium tetrafluo-roborate an unsymmetrical structure 101 was predicted from its NMR data (Scheme 40). 

The oxidation behavior of 3-oxa-chromanols was mainly studied by means of the 2,4-dimethyl-substituted compound 2,4,5,7,8-pentamethylM /-benzo[ 1,3]dioxin-6-ol (59) applied as mixture of isomers 27a it showed an extreme dependence on the amount of coreacting water present. In aqueous media, 59 was oxidized by one oxidation equivalent to 2,5-dihydroxy-3,4,6-trimethyl-acetophenone (61) via 2-(l-hydroxyethyl)-3,5,6-trimethylbenzo-l,4-quinone (60) that could be isolated at low temperatures (Fig. 6.41). This detour explained why the seemingly quite inert benzyl ether position was oxidized while the labile hydroquinone structure remained intact. Two oxidation equivalents gave directly the corresponding para-quinone 62. Upon oxidation, C-2 of the 3-oxa-chroman system carrying the methyl substituent was always lost in the form of acetaldehyde. 

Cleavage of carbon-nitrogen bonds adjacent to the carbonyl function can occur during the Clemmensen reaction. In most cases these reactions passed unnoticed until tlie products were re-examined by N. J. Leonard [117]. The processes were termed abnormal Clemmensen reactions. Prior to this work, the only unusual Clemmensen reduction processes noted were of (o-butoxy-2,4-dihydroxy-acetophenone which gives 1-etliyl-2,4-dihydroxybenzene [118] and of co-dimethylaminoacetophenone which gives ethylbenzene and dimetiiylamine [119],... 

C10H13NO3 2,4-Dihydroxy-5-ethyl-acetophenone oxime Gravimetric Te 35... 

Ilex pubescens Hook Am. Mao Dong Qing (Holly) (leaf, root) Flavone, ursolic acid, scopoletin, 3,4-dihydroxy acetophenone, hydroquinone, vomifliol.33 Treat angina pectoris, acute myocardial infarction, central angiospastic retinitis, cerebral thrombosis, thrombophlebitis. 

A variety of aromatic esters undergo light-induced rearrangements similar to the Fries rearrangement. Irradiation of 2-hydroxyphenyl acetate (Formula 419) gives o-dihydroxybenzene (Formula 420) (46%), 2,3-dihydroxyacetophenone (Formula 421) (22%) and 3,4-dihydroxy-acetophenone (Formula 422) (18%) (186). Phenyl acetate gives 2-... 

Reaction of 9-bromomethyl-4-oxo-4//-pyrido[ 1,2-a]pyrimidine-3-carboxylates 505 and their homologs with 2,4-dihydroxy-3-propyl-and -3-allyl-acetophenone 506 in boiling methyl ethyl ketone in the presence of potassium carbonate afforded 9-(4-acetyl-3-hydroxy-2-substituted phenoxymethyl) derivatives (507) [87EUP242230 88JAP(K)88/246375]. 

The required 4,7-dihydroxy coumarins were prepared from resorcinol using known methods [81]. Postulated structures of the newly synthesized compounds 39a-d, 40a-d, 41a-d and 42a-d were in agreement with their IR, 1H NMR spectral and elemental analysis data. In the IR spectrum of compound 39a, (R = 6-CH3) exhibited prominent bands around 1709, 1648 and 3042 cm-1 due to carbonyl lactone of coumarin, carbonyl of acetophenone... 

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