Red blood cells, antibody

Van Loveren, H., Verlaan, A.P. and Vos, J.G. (1991) An enzyme linked immrmosorbent assay of anti-sheep red blood cell antibodies of the classes... 

Hows J, Beddow K, Gordon-Smith E, Branch DR, Spruce W, Sniecinski I, Krance RA, Petz LD. Donor-derived red blood cell antibodies and immune hemolysis after allogeneic bone marrow transplantation. Blood 1986 67(1) 177-81. 

Nanobiotechnology-based methods, including nanoparticles such as liposomes Glass-like sugar matrices Resealed red blood cells Antibody-targeted systems... 

Blood Type Type of Oligosaccharide Antigens Present on Red Blood Cells Antibody in Serum l pes of Serum That Cause Agglutination When Mixed with Red Blood Cells... 

Type n immunopathologic reactions involve destruction of host cells (usually blood cells) through cytotoxic antibodies by one of two mechanisms (see Fig. 86-1). First, the drug binds to the cell as a hapten (e.g., the platelet or red blood cell). Antibodies (IgG or IgM) specific for the... 

Rabbit anti-(human type-0 red-blood cells) antibody Rabbit immunoglobulin IgG anti-(a-amylase) antibody... 

Sakem B, Matozan K, Nydegger UE, Weigel G, Griesmacher A, Risch L. Anti-red blood cell antibodies, ft ee light chains, and andphospho-lipid antibodies in intravenous immunoglobulin preparations. Israel Med Assoc J IMAJ October 2013 15(10) 617-21. 

The agglutination of incompatible red blood cells, which indicates that the body s immune system has recognized the presence of foreign cells in the body and has formed antibodies against them, results from the presence of polysaccharide markers on the surface of the cells. Types A, B, and O red blood cells... 

Miller Scott (1985) reported marked reduction in thymus weight in rats fed dioctyltin dichloride for 8 or 12 weeks at a level of 75 mg/kg diet. Numbers of lymphocytes together with T cell subpopulations were reduced in treated rats, but no difference was seen in antibody response to sheep red blood cells in vivo. No evidence was foimd of in vitro cytocidal effects of dioctyltin dichloride on blood lymphocytes. Evans et al. (1986) dosed pregnant and non-pregnant rats for 3 weeks at 75 mg/kg diet and reported severe thymic atrophy and extensive vacuolation of reticuloendothelial cells in pregnant animals only. 

Peeters, P. A. M., Brunink, B. G., Eling, W. M. C., and Crommelin, D. J. A. (1989). Therapeutic effect of chloroquirie (CQ) containing immunoliposomes in rats infected with Plasmodium berghei parasitized mouse red blood cells comparison with combinations of antibodies and CQ or liposomal CQ, Biochim. Biophys Acta, 981, 269-276. 

Immunologic abnormahties (eg, transfusion reactions, the presence in plasma of warm and cold antibodies that lyse red blood cells, and unusual sensitivity to complement) also fall in this class, as do toxins released by various infectious agents, such as certain bacteria (eg, Clostridium). Some snakes release venoms that act to lyse the red cell membrane (eg, via the action of phospholipases or proteinases). 

Astaxanthin has been shown to enhance in vitro antibody production by mouse spleen cells stimulated with sheep red blood cells and in human blood cells in vitro. Furthermore, it has not exhibited any mutagenicity in an in vitro study at doses up to 14.4 mg/day for 2 weeks. 

Type AB blood contains A and B antigens on the red blood cells. Therefore, individuals with this blood type produce neither anti-A nor anti-B antibodies and can receive a transfusion of any blood type. Individuals with type AB blood are referred to as universal recipients. 

Another type of cell surface antigen found on red blood cells is the Rh factor. Red blood cells that contain the Rh factor are referred to as Rh-positive and RBCs without this factor are referred to as Rh-negative. This antigen also stimulates antibody production. Therefore, Rh-negative individuals that produce anti-Rh antibodies should receive only Rh-negative blood. Rh-positive individuals that do not produce anti-Rh antibodies can receive Rh-negative or Rh-positive blood. Approximately 85% of Caucasians are Rh-positive and 15% are Rh-negative. Over 99% of Asians, 95% of American blacks, and 100% of African blacks are Rh-positive. 

P. D Orazlo and G.A. Rechnitz, Ion electrode measurements of complement and antibody levels using marker-loaded sheep red blood cell ghosts. Anal. Chem. 49, 2083-2086 (1977). 

Human IgG monoclonal antibody C5 IgG Anti-human globulin reagent for phenotyping and crossmatching red blood cells of receivers and donors M. sativa 35 S MSP + 0.13-1.0% TSP 38... 

The answer is a. (Katzung, p 162.) Many drugs can cause an immunohemolytic anemia. Methyldopa may cause a positive Coombs test in as many as 20% of patients, along with hemolytic anemia. Other drugs with similar actions on red blood cells are penicillins, quinidine, procainamide, and sulfonamides. These form a stable or unstable hapten on the red cell surface, which induces an immune reaction I immunoglobulin G (IgG) antibodies] and leads to dissolution of the membrane. 

In rodents, sheep red blood cells (SRBC) are routinely used for immunization. The antibody response is determined using the plaque forming cells assay (PFC) or by plasma SRBC-specific antibody titer [21, 22], As an alternative to SRBC, other T-cell-dependent antigen may be used, including keyhole limpet hemocyanin (KLH), tetanus toxoid (TT), or pneumococcal antigen. 

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