Bone marrow transplantation allogeneic

Close monitoring of HCT recipients for infections is necessary because recovery of immune function is slow, sometimes requiring over 2 years, even in the absence of immunosupressants.104 Fevers should be assessed and treated rapidly to minimize the likelihood of a fatal infection. HCT recipients—both autologous and allogeneic—lose protective antibodies to vaccine-preventable diseases the CDC and the European Group for Bone Marrow Transplantation have issued recommendations for reimmunization for HCT recipients.107... [Pg.1463]

Anonymous. Allogeneic peripheral blood stem-cell compared with bone marrow transplantation in the management of hematologic malignancies An individual patient data meta-analysis of nine randomized trials. J Clin Oncol 2005 23 5074-5087. [Pg.1464]

Hildebrandt GC, Duffner UA, Olkiewicz KM, et al. A critical role for CCR2/ MCP-1 interactions in the development of idiopathic pneumonia syndrome after allogeneic bone marrow transplantation. Blood 2004 103(6) 2417-2426. [Pg.255]

G-CSF and GM-CSF have also found application after allogenic or autologous bone marrow transplantation, to accelerate neutrophil recovery. (Allogenic means that donor and recipient are different individuals, and autologous means that donor and recipient are the same.)... [Pg.272]

Ochs, L. et al., Late infections after allogeneic bone marrow transplantations comparison of incidence in related and unrelated donor transplant recipients, Blood, 86, 3979, 1995. [Pg.46]

Autologous bone marrow transplant Neutropenia resulting from chemotherapy Allogeneic bone marrow transplant Peripheral blood progenitor cell mobilization Leukemias (leukopenias and fungal infection) March 1991 Sept. 1995 Nov. 1995 Dec. 1995 Nov. 1996... [Pg.146]

Chemotherapy-induced neutropenia Neutropenia during bone marrow transplant Severe chronic neutropenia Autologous or allogeneic bone marrow transplantation Mobilization of autologous PBPCs after chemotherapy Persistent or recurrent cutaneous T cell lymphoma Feb. 1991 June 1994 Dec. 1994 Dec. 1995 April 1998 Feb. 1994... [Pg.146]

Baud 0, Goulet O, Canioni D, et al Treatment of the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) by allogeneic bone marrow transplantation. N Engl J Med 2001 344 1758-1762. [Pg.219]

The experience shows that HSC transplantation (peripheral blood, bone marrow, and cord blood) is the effective method of treatment of oncological and hematological diseases. The number of transplantation centers and HSC transplantations carried out in them increases every year. For example, the European Group of Blood and Bone Marrow Transplantation (EBMT) included 145 transplantation centers from 20 European countries in 1990, and the number increased to 592 centers functioning in 38 European and 5 non-European countries in 2004. While 4234 autologous and allogeneic... [Pg.253]

HSC transplantations of peripheral blood were carried out in the Kyiv center of bone marrow transplantation during 2001-2005. That includes 2001 -30 transplantations, 2002 - 46, 2003 - 36, 2004 - 32, and 2005 - 30. Most of the transplantations were autologous. One allogeneic transplantation from relative donors was successfully carried out each 2003, 2004 and 2005. [Pg.257]

Bone marrow transplantation, particularly allogenic transplantation, is often a treatment of choice for individuals suffering from acute or chronic leukaemia, aplastic anaemia or various stem cell-related genetic disorders (e.g. thalassaemias). [Pg.263]

Patients who have received an allogeneic bone marrow transplant characteristically display depressed serum EPO levels for up to 6 months post-transplantation. Administration of EPO thus seems a logical approach to counteract this effect. Several clinical studies have validated... [Pg.272]

CassUeth PA, Harrington DP, Appelbaum FR, Lazarus HM, Rowe JM, Paietta E et al. Chemotherapy compared to autologous or allogeneic bone marrow transplantation in the management of acute myeloid leukaemia in first remission. N Engl J Med 1998 339 1649-56. [Pg.724]

Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) has occurred in patients with advanced HIV disease and also in allogeneic bone marrow transplant and renal transplant recipients taking valacyclovir at doses of 8 g/day. [Pg.1290]

G. Other applications Other possible uses of Orthoclone OKT3 are for prophylaxis and treatment of acute graft-versus-host disease (as an adjunct with allogeneic bone marrow transplantation) treatment of rejection after lung transplantation prophylaxis and treatment of rejection... [Pg.290]

Markus, P. M., Cai, X., Ming, W., Demetris, A. j., Fung, j. j., and Starzl, T. E. (1991). FK 506 reverses acute graft-versus-host disease after allogeneic bone marrow transplantation in rats. Surgery 110, 357-364. [Pg.256]

Brochstein JA, Keman NA, Groshen S, Cirricione C, et al. 1987. Allogenic bone marrow transplantation after hyperfractionated total body irradiation and cyclophosphamide in children with acute leukemia. NEJM. 317 1618-1624. [Pg.103]

Hagglund H, Remberger M, Klaesson S, LonnqvisL B, Ljungman P, Ringden O. Norethisterone treatment, a major risk-factor for veno-occlusive disease in the liver after allogeneic bone marrow transplantation. Blood 1998 92(12) 4568-72. [Pg.243]

Prevention of type 1 diabetes in nonobese diabetic mice by allogeneic bone marrow transplantation. Proc. Natl. Acad. Sci. USA 82, 7743-7747. [Pg.133]

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