Project methodologies

As experts in pharmaceutical marketplace analytics and projection methodologies, forecasters can assess the commercial potential of the development compound and work closely with the marketer/brand manager to develop a prescription and revenue projection for the NCE. Forecasters are often technically oriented and their role is to provide a numerical forecast for the compound, not focus on the strategic implications of their analysis. However, their interaction with the other members of the brand plan team often clarifies the assumptions associated with the disease marketplace and the place of the NCE within it. 

A project review process that is consistent with both the Dow Management of Change process and the Dow Global Project Methodology process. 

Raw materials, process streams, products and waste of any new process that has reached the pilot or production plant stage shall be reviewed and evaluated to determine if any potential reactive chemical hazards are involved. The GPM process fGlobal Project Methodology) requires an evaluation of the need to complete a project version review of the RC/PHA (Reactive Chemicals Process Hazard Assessment) review. This evaluation and recommendation is to be done by a member of the Process Safety Technology Center organization and should follow the RC/PHA protocol. 

Validation Approach The project methodology to be followed for validation of LIMS must be clearly defined in the Validation Plan to ensure that the most efficient approach is taken. This document should provide the project team and the LIMS Suppfier/Integrator with sufficient detail to allow the appropriate documentary evidence to be produced to support the finally handed over compliant system. It is important that the Validation Plan (or at least the relevant information) be issued to the LIMS Supplier/Integrator to ensure that no surprises regarding the validation expectations occur at a later stage in the project. It is acceptable for the supplier, integrator, and customer to use different validation methodologies, provided that the customer ... 

Protocol Offset Project Methodology, U.S. Envirormiental Protection Agency, 2008. 

Florida Commission on Hurricane Loss Projection Methodology (FCHLPM) 2007. Florida Public Hurricane Loss Model Acceptability Notification. Available on http //www.sbafla.com/methodology/index.asp. 

There are well-established demand projection methodologies developed by industrial organizations and companies, however, they..were.not disseminatedip.r. public use. 

Actually this methodology is regularly applied to fragrances however, it was further deployed on such other axes as skincare for instance. From our experience, the more evocative the products are, the more relevant this projective methodology tends to be. 

Smith, S.K., J. Tayman, and DA. Swanson. 2001. State and Local Population Projections Methodology and Analysis, New York Kluwer. 

Lagrange multipliers Xo and Xs are determined by the asymptotic projection methodology [10, 11, 40]. In practical applications, we invariably invoke the algebraic approximation by parameterizing the orbitals in a finite basis set This approximation may be written... 

Our experiences with the software developed within the ANDES project have shown that CBR is a helpful methodology for use in the interpretation of NDT data from field inspections. Because CBR systems can adapt to new situations they can cope with inspection of varying constructions in varying conditions. However, because CBR systems learn from classifications made by the operator this means that they will not be very useful for completely automatic interpretation. Fortunately, most of the NDT inspection requires the presence of an operator because of the required high reliability. 

Human error probabilities can also be estimated using methodologies and techniques originally developed in the nuclear industry. A number of different models are available (Swain, Comparative Evaluation of Methods for Human Reliability Analysis, GRS Project RS 688, 1988). This estimation process should be done with great care, as many factors can affect the reliability of the estimates. Methodologies using expert opinion to obtain failure rate and probability estimates have also been used where there is sparse or inappropriate data. 

The case studies that follow have mainly come from live product development projects in industry. Whilst not all case studies require the methodology to predict an absolute capability, a common way of applying CA is by evaluating and comparing a number of design schemes and selecting the one with the most acceptable performance measure, either estimated Cp, assembly risk or failure cost. In some cases, commercial confidence precludes the inclusion of detailed drawings of the components used in the analyses. CA has been used in industry in a number of different ways. Some of these are discussed below ... 

Fiksel, J. et al., 1982, Development, Application and Evaluation of a Value-Impact Methodology for Prioritization of Reactor Safety R D Projects, EPRI NP-2530, August. 

The design methodology does not take a position on who does this or that task. That is part of administrative or commercial flow, which varies in different parts of the world and even in different projects in one country. 

Product realization in the automotive industry is either called advanced product quality planning (APQP) or project management. In terms of their objectives there is no difference. In terms of the mechanics there may be some differences, depending on the methodologies employed by the organization. 

Remember that the objectives of the pilot are to refine the integration methodology and to estimate the expected costs of the project and benefits that integration will provide. 

This chapter summarizes climate projections presented by the recent Fourth Assessment Report (AR4) of the IPCC, both for the global scale and for the so-called European and Mediterranean region. Besides the IPCC projections, other results regarding the Mediterranean area will be reviewed as well. The emphasis will be mostly placed on temperature and precipitation projections, while other variables, such as wind, solar radiation, or sea level, will not be commented in depth. Some attention will be paid to methodologies used to develop projections, and the corresponding uncertainties will be commented. In general, projections will be given for the end of the current century. 

---