Bacterial pneumonias

AN AMPEROMETRIC ENZYME IMMUNOSENSOR BASED ON SCREEN-PRINTED ELECTRODE FOR THE DETERMINATION OF KLEBSIELLA PNEUMONIAE BACTERIAL ANTIGEN... 

The aim of our investigation was the development of the amperometric enzyme immunosensor for the determination of Klebsiella pneumoniae bacterial antigen (Ag), causes the different inflammatory diseases. The biosensing pail of the sensors consisted of the enzyme (cholinesterase) and antibodies (Ab) immobilized on the working surface of the screen-printed electrode. Bovine seiaim albumin was used as a matrix component. 

Pneumonia - bacterial Pneumonia - viral Radiculopathy - Guillain-Barre type Reye s syndrome [6] A Rhabdomyolysis Toxic shock syndrome... 

Indications Bone and joint infections, bacterial bronchitis, endocervical and urethral chlamydia, bacterial gastroenteritis, endocervical and urethral gonorrhea, intra-abdominal infections, empiric therapy for febrife neutropenia, pelvic inflammatory disease, bacterial pneumonia, bacterial prostatitis, acute sinusitis, skin and soft tissue infections, typhoid fever, bacterial urinary tract infections, chancroid, meningococcal carriers, bacterial septicemia, prophylaxis in prevention of bacterial urinary tract infections Common drug examples ... 

GRO and IL-8 in patients with ARDS or pneumonia (bacterial or P. carinii)... 

Boiselle PM, Tocino I, Hooley RJ, Pumerantz AS, Selwyn PA, Neklesa VP, Lange RC (1997) Chest radiograph interpretation of Pneumocystis carinii pneumonia, bacterial pneumonia, and pulmonary tuberculosis in HIV-positive patients accuracy, distinguishing features, and mimics. JThorac Imaging 12 47-53... 

It was established that Ab to Klebsiella pneumoniae didn t demonstrate the cross-reactivity to antigens of the relative bacterial species so, it could be considered that antibodies investigated was highly specific only to the own antigen. The physical-chemical characteristics of the immunological interaction such as constants of formation of Ag-Ab complex were obtained. The binding constants of immune complex were Ka =(9.7 l.l)-10 and Ka,=(1.7+0.3)T0 (mg/ml)f... 

The natural and semi ynthetic penicillins are used in tire treatment of bacterial infections due to susceptible microorganisms. Fbnicillins may be used to treat infections such as urinary tract infections, septicemia, meningitis, intra-abdominal infection, gonorrhea, syphilis, pneumonia, and other respiratory infections. Examples of infectious microorganisms (bacteria) that may respond to penicillin therapy include gonococci, staphylococci,... 

Meropenem (Merrem IV) inhibits syndiesis of die bacterial cell wall and causes die deadi of susceptible cells. This drug is used for intra-abdominal infections caused by Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, and odier susceptible organisms Meropenem also is effective against bacterial meningitis caused by Neisseria meningitidis, Streptococcus pneumoniae, and Hemophilus influenzae. 

Extensive screening methodology was used to find the suitable microorganism. As a result, K. pneumoniae IFO 3319 out of 450 bacterial strains was found to give the corresponding (2J, 3S)-hydroxy ester with 99% de and >99% ee in kilogram scale quantitatively [29g]. 

Many bacterial polysaccharides contain phosphoric ester groups. There is a limited number of examples of monoesters. More common are phosphoric diesters, connecting an amino alcohol or an alditol to the polysaccharide chain. Another possibility is that oligosaccharide or oligosaccharide-alditol repeating units are connected to a polymer by phosphoric diester linkages. In addition to the intracellular teichoic acids, several bacteria, for example, different types of Streptococcus pneumoniae, elaborate extracellular polymers of this type. These polymers are generally discussed in connection with the bacterial polysaccharides. 

Although viral infections are important causes of both otitis media and sinusitis, they are generally self-limiting. Bacterial infections m complicate viral illnesses, and are also primary causes of ear and sinus infections. Streptococcus pneumoniae and Haemophilus influenzae are the commonest bacterial pathogens. Amoxycillin is widely prescribed for these infections since it is microbiologically active, penetrates the middle ear, and sinuses, is well tolerated and has proved effective. 

Fractionation. The process by which components are extracted firm bacterial eells or from the medium in whieh the baeteria are grown and obtained in a purified form. The polysaccharide antigens of Neisseria meningitidis are separated from the bacterial cells by treatment with hexadecyltrimethylammonium bromide and those of Streptococcus pneumoniae with ethanol. The purity of an extracted material may be improved by resolubilization in a suitable solvent and precipitation. After purification, a component may be dried to a powder, stored indefinitely and, as required, incorporated into a vaccine in precisely weighed amounts at the blending stage. 

Nosocomial bacterial pneumonia developing in patients on mechanical ventilation... 

Routine antibiotic use is not warranted because the primary infectious agents associated with asthma exacerbations are viruses.2,3 Antibiotics should be reserved for situations when bacterial infection is strongly suspected (e.g., fever and purulent sputum, pneumonia, and suspected sinusitis). 

Increased insensible losses (from his fever caused by bacterial pneumonia) and lack of access to water (from his altered level of consciousness)... 

The vast majority of conjunctivitis cases are viral in nature. For acute bacterial conjunctivitis, the cause is primarily grampositive organisms.11 The primary pathogens in acute bacterial conjunctivitis are Streptococcus pneumoniae, Staphylococcus aureus, or Haemophilus influenzae.12... 

Disruption of host defenses owing to intravenous catheters, indwelling Foley catheters, burns, trauma, surgery, and increased gastric pH (secondary to antacids, H2 blockers, and proton pump inhibitors) may place patients at higher risk for infection. Breaks in and entry into the skin provide a route for infection because the natural barrier of the skin is disrupted. Increased gastric pH can allow for bacterial overgrowth and has been associated with an increased risk of pneumonia.18... 

Bacterial meningitis is the most common cause of CNS infections. An epidemiologic review of bacterial meningitis in 1995 revealed that Streptococcus pneumoniae (pneumococcus) was the most common pathogen (47%), followed by Neisseria... 

S. pneumoniae, N. meningitidis, and H. influenzae type b dramatically. Prior to the availability of Hib conjugate vaccines, Hib meningitis or other invasive disease was documented in 1 in 200 children by the age of 5 years.5 Widespread use of the Hib vaccine has reduced the incidence of invasive Hib disease by 99% and has shifted the age distribution of bacterial meningitis to older age groups (from 15 months in 1986 to 25 years in 1995).1,6 Recent data indicate that routine use of the 7-valent... 

The etiology of bacterial pneumonia varies in accordance with the type of pneumonia. 

Streptococcus pneumoniae is the most common bacterial pathogen associated with community-acquired pneumonia. 

TABLE 68-1. Common Bacterial Pathogens by Type of Pneumonia... 

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