White soft paraffin

Oilatum light liquid paraffin, white soft paraffin... 

Liquid paraffin, white soft LacriLube Allergan... 

Lawrence CM, Smith AG. Ampliative medicament allergy concomitant sensitivity to multiple medicaments including yellow soft paraffin, white soft paraffin, gentian violet and Span 20. Contact Dermatitis 1982 8(4) 240-5. 

Water, purified 995 g Paraffin, white soft q.s. for supplementing the evaporated... 

Simone and Popino have considered the stability of neomycin in both hydrophobic and hydrophilic ointment bases. No loss of potency over a period of 1 year at 20°C was reported for formulations containing carboxymethylcellulose, polyethylene glycol(P.E.G.) or white-soft paraffin. However, formulations containing hydrous lanolin were reported to be unstable. All materials used in the formulations were obtained from U.S. sources. Coates et al3°l investigated the use of P.E.G. from British sources and described neomycin as being incompatible with the materials tested. 

Therefore 15 g of the 1% hydrocortisone ointment need to be diluted with white soft paraffin to make up 30 g of 0.5% hydrocortisone ointment. 

Second, dead lambs were smeared with neatsfoot oil (an oil obtained by boiling feet and leg bones of cattle), left with the mother for 2-18 hours and then substituted by neatsfoot oil-treated foster lambs. Here 91% were accepted. The best acceptance rate (100%), however, was achieved by draping the skin of the dead lamb over the alien one. This is the method of choice because it is not only most effective but also saves labor as no treatment is necessaiy (Alexander eta/., 1987). Ewes accept alien lambs if they are rubbed with non-polar oils such as white soft paraffin or liquid paraffin. Polar materials such as polyethylene glycol, glycerol silicone, or diisooctyl phthalate have no effect. Ewes appear to use non-polar volatiles for discrimination (Alexander etal., 1989). 

Eczema may be so mild that no treatment is required beyond avoiding known irritants and applying a soothing and protective ointment which keeps the skin moist and so reduces inflammation. There are many such over-the-counter remedies based on liquid paraffin and soft white paraffin, both of which are hydrocarbons obtained from refined petroleum and which contain nothing that can irritate the skin. Liquid paraffin is also called mineral oil and is available under a variety of trade names, such as Nujol, while soft white paraffin is better known as Vaseline. Emulsified mixtures of liquid paraffin and soft white paraffin make excellent skin creams. 

Paraffin gauze is bleached cotton or combined cotton and rayon cloth impregnated with yellow or white soft... 

Longworth, A.R. Prench, J.D. Quality control of white soft paraffin. J. Pharm. Pharmacol. 1969, 21, 1S-5S. 

Barry, B.W. Grace, A.J. Grade variation in the rheology of white soft paraffin BP. J. Pharm. Pharmacol. 1970, 22, 147S-156S. 

White soft paraffin and yellow soft paraffin are mixtures of semi-solid hydrocarbons. They are used as bases for ointments, as emollients in skin diseases, and as lubricants in treating dry eyes. Soft paraffin is also known as petroleum jelly, petrolatum, and Vaseline. 

Although soft paraffin has been used to treat irritant contact dermatitis (17) and to protect the skin from other sensitizers (18), hypersensitivity reactions can occur, but are rare (19-26). Yellow soft paraffin is slightly more antigenic than white soft paraffin (24). Contact sensitization to a neat cutting oil containing chlorinated paraffin occurred in 12 men (27). Contact urticaria mimicking dermatitis has also been reported (28). 

Synonyms vaselinum album white petroleum jelly white soft paraffin. 

Amerchol CAB- Porlan 500 petrolatum and wool alcohols white soft paraffin and lanolin alcohols yellow soft paraffin and lanolin alcohols. 

Anionic emulsifying wax (3-30%) may also be mixed with soft and liquid paraffins to prepare anhydrous ointment bases such as emulsifying ointment BP. A preparation of 80% anionic emulsifying wax in white soft paraffin has been used as a soap substitute in the treatment of eczema. 

In an attempt to reduce the photodegradation of a development compound, Merrifield et al. (1996) compared the free acid of compound to a number of its salts, each of which they incorporated into a white soft paraffin base. Their results (Table 6.12) showed that after a 1 h exposure in a SOL2 light simulation cabinet, the disodium salt showed significant degradation. 

Oil phase Mineral oil Isopropyl myristate Beeswax Cottonseed oil Cetostearyl alcohol Lanolin (and derivatives) White soft paraffin Yellow soft paraffin Canola oil Cetyl alcohol Arachis (peanut) oil Oleic acid Isopropyl palmitate Castor oil Stearyl alcohol Jojoba oil Stearic acid Silicone oils... 

Table 13.5 Light Stability of Compound B as Free Acid and Various Salt Forms Incorporated into a White Soft Paraffin Base...

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