Mononucleosis, infectious

GVL Graft-versus-leukemia IM Intramuscular infectious mononucleosis... 

Dysmotility has been reported in Lyme disease [166] and in postviral syndromes associated with cytomegalovirus and herpes simplex virus [167], Altered intestinal motility can also be part of infectious mononucleosis [168]. 

VassalloM, Camilleri M, Caron BL, Low PA Gastrointestinal motor dysfunction in acquired selective cholinergic dysautonomia associated with infectious mononucleosis. Gastroenterology 1991 100 252-258. 

Immunocytochemical methods were developed to detect specific antibodies in sera from patients affected by different infectious diseases. P3-HR1 cells, which express Epstein-Barr-virus-induced virus capsid antigens (VCA), were used to search for specific human IgM (class M immunoglobulins) to VCA in infectious mononucleosis patients. After treatment of cells with serial dilutions of sera, HRP-conjugated anti-IgM antibody was added and detected with CL substrate [25],... 

Suggested Alternatives for Differential Diagnosis Influenza, infectious mononucleosis, hepatitis, leptospirosis, infective endocarditis, malaria, tuberculosis, typhoid fever, cryptococcosis, histoplasmosis, ankylosing spondylitis and undifferentiated spondyloarthropathy, collagen vascular disease, chronic fatigue syndrome, malignancy, and osteomyelitis. 

Suggested Alternatives for Differential Diagnosis Adenoviruses, arenaviruses, California encephalitis, coxsackieviruses, cytomegalovirus, dengue fever, eastern equine encephalitis, echoviruses, infectious mononucleosis, Japanese encephalitis, Lyme disease, meningitis, parainfluenza virus, rhinoviruses, bacterial sepsis, severe acute respiratory syndrome (SARS), St Louis encephalitis, upper respiratory infection, Venezuelan encephalitis, and West Nile encephalitis. 

Suggested Alternatives for Differential Diagnosis Dengue, measles, Rocky Mountain spotted fever, rubella, tick bite fever, epidemic typhus, Q fever, typhoid, malaria, trypanosomiasis, hepatitis, infectious mononucleosis, herpes, and influenza. 

Suggested Alternatives for Differential Diagnosis Anthrax, brucellosis, dengue, ehrlichiosis, infectious mononucleosis, Kawasaki disease, leptospirosis, malaria, meningitis, men-ingococcemia, relapsing fever, Rocky Mountain spotted fever, syphilis, toxic shock syndrome, toxoplasmosis, tularemia, typhoid fever, rubella, measles. 

Common childhood vaccines include the three-in-one measles, mumps and rubella and the diphtheria vaccine. Infectious mononucleosis, also knov/n as glandular fever, is caused by the Epstein-Barr virus and no vaccine is available. 

A viral etiology has been implicated in Burkitt s lymphoma, and there is some evidence that Epstein-Barr virus causes infectious mononucleosis in Europe and Burkitt s lymphoma in Africa. It has been suggested that if the cause of the Burkitt s lymphoma is viral, then entry of the virus particles into the lymphoid colls of the body may derange a part of the cell immune process, subsequently affecting the production of the IgM antibody, a theory which is compatible to the dysproteinemia sometimes seen in multiple myeloma and other lymphomas (N2). Also in support of this is the observation that C-reactive protein was markedly elevated in the serum of patients with Burkitt s lymphoma, and disappeared entirely from the blood when they were cured (MIO). The relationship between malarial infection and Burkitt s lymphoma has been dealt with in a previous section on malaria. 

Hypersensitivity Fever, skin eruptions of various types, including exfoliative dermatitis, infectious mononucleosis-like, or lymphoma-like syndrome, leukopenia, agranulocytosis, thrombocytopenia, Coombs positive hemolytic anemia, jaundice, hepatitis, pericarditis, hypoglycemia, optic neuritis, encephalopathy, Leoffler s syndrome, vasculitis, and a reduction in prothrombin. 

Lymphadenopathy Patients who receive tacrolimus ointment and who develop lymphadenopathy should have the etiology of their lymphadenopathy investigated. In the absence of a clear etiology for the lymphadenopathy, or in the presence of acute infectious mononucleosis, consider discontinuation of tacrolimus ointment. Monitor patients who develop lymphadenopathy to ensure that the lymphadenopathy resolves. 

Although infections are generally thought to be particularly frequent and possibly severe in patients treated with steroids, they have been used as short-term adjunctive therapy to reduce the severe symptoms associated with such bacterial infections as acute H. influenzae and miliary tuberculosis and in viral infections, such as hepatitis and infectious mononucleosis. 

B virus have been reported in cases of infectious mononucleosis. 

Unlabeled Uses Oral, parenteral Prophylaxis of herpes simplex and herpes zoster infections, infectious mononucleosis. 

Infectious mononucleosis. sesses antimalarial activity similar to that... 

Non-specific itching rashes, e.g. sulphonamides, penicillins, ampicillin in infectious mononucleosis... 

The Epstein-Barr viruses play an etiological role in infectious mononucleosis, an acute infections disease that affects lymphoid tissue throughout the body. A strong association of this virus with Burkitf s lymphoma and perhaps nasopharyngeal carcinoma also has been observed. 

A number of virus diseases and virus related topics are described in this encyclopedia. Check alphabetical index for antiviral drugs, cancer research, cluckenpox, common cold coxsackie virus, dengue (breakbone fever), hepatitis, infectious mononucleosis, influenza, measles, mumps, Norwalk virus, poliomyelitis, rabies. Rift Valley fever, vaccinia, virus diseases (plants), and yellow fever. 

The first scientific report of an orally transmitted outbreak of Chagas disease in Brazil was made in 1968 (Nery-Guimaraes et ah, 1968). This occurred in the district of Teutonia, municipality of Estrela (Rio Grande do Sul state) in the year 1965, between March 13 and March 22. Seventeen people from an Agricultural School (workers, students, and lecturers that usually had meals there) fell sick. The initial unconfirmed diagnosis was typhoid fever. Other possible diagnoses like infectious hepatitis, toxoplasmosis, infectious mononucleosis, and food poisoning were also discarded. Then, some of the infected people presented with clinical symptoms of acute myocarditis, and, based on clinical observations,... 

Herpesviridae Cytomegalovirus Epstein-Barr virus Herpes simplex, types 1 and 2 Varicella-zoster virus Cytomegalic inclusion disease (i.e., widespread involvement of virtually any organ, especially the brain, liver, lung, kidney, intestine) Infectious mononucleosis Local infections of oral, genital, and other mucocutaneous areas systemic infections Chickenpox herpes zoster (shingles) other systemic infections... 

C8. Charlesworth, J. A., Quin, J. W., MacDonald, G. J., Lennane, R. J., and Boughton, C. R., Complement lymphocytotoxins and immune complexes in infectious mononucleosis Serial studies in uncomplicated cases. Clin. Exp. Immunol. 34, 241-247 (1978). 

W3. Wallace, M., Leet, G., and Rothwell, P., Immune complex-mediated glomerulonephritis with infectious mononucleosis. Aust. N. Z. J. Med. 4, 192-195 (1974). 

Increased in severe viral infections such as mumps, varicella (chicken pox), influenza A and B, common cold, viral meningitis, infectious mononucleosis, measles (rubeola), or rotavirus-V enteritis. Severe viral infections are defined by increased lymphocyte count. 

Barr virus confirmed that he had infectious mononucleosis. He was kept in bed for 2 weeks, by which time the signs of inflammation and hepatocellular damage entirely disappeared. However, mild anemia (hemoglobin 110-120 g/L) with reticulocytosis (50%-6.0%), increased serum unconjugated bilirubin, and splenomegaly still remained, suggesting the presence of persistent hemolysis. The physician therefore performed further examinations to confirm the diagnosis of hemolytic anemia. 

Infectious mononucleosis Risk of developing skin rash... 

Acute dacryoadenitis usually responds rapidly to systemic corticosteroids. Patients with viral dacryoadenitis associated with acute epidemic parotitis (mumps), infectious mononucleosis, or herpes zoster infection should receive supportive therapy, such as rest, local application of ice, and use of oral analgesics, such as acetaminophen. Supportive therapy for mumps should be continued for its typical 2- to 4-week self-limiting course. 

Drugs can give diagnostic clues, e.g. ampicillin and amoxicillin causing rash in infectious mononucleosis — a diagnostic adverse effect, not a diagnostic test. 

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