Chronic fatigue syndrome

Suggested Alternatives for Differential Diagnosis Influenza, infectious mononucleosis, hepatitis, leptospirosis, infective endocarditis, malaria, tuberculosis, typhoid fever, cryptococcosis, histoplasmosis, ankylosing spondylitis and undifferentiated spondyloarthropathy, collagen vascular disease, chronic fatigue syndrome, malignancy, and osteomyelitis. 

See, D.M. et al., In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency syndrome patients, Immunopharmacology, 35, 229, 1997. 

Mental disorders, for example, multiple subtypes of anxiety, chronic fatigue syndrome, depression, sometimes together with chronic pain, posttraumatic stress disorders (PTSD), and schizophrenia... 

J. N. Baraniuk, B. Casado, H. Maibach, D. J. Clauw, L. K. Pannell, and S. S. Hess. A Chronic Fatigue Syndrome-Related Proteome in Human Cerebrospinal Fluid. BMC Neurology, 5(2005) 22. 

If I m having a bad day I sometimes still write, unless a reaction to a chemical is affecting my brain. When I can t think clearly, I can t write. And sometimes I feel so apathetic that I can t write. But I m thankful that I have the skill. I think education is so important to prevent others from getting this illness. I believe that chronic fatigue syndrome, fibromyalgia, sick building syndrome and similar conditions with other names are all forms of MCS. They ll find that out with more studies. People just don t know what s wrong with them. They think they ve got asthma, depression, attention deficit disorder and a lot of other problems that can be related to chemical exposures. 

The most recent SPECT scan (single photon computed tomography of the brain) studies, by a Harvard School of Public Health physician and researcher, have shown that people with MCS have blood flow patterns in the brain that are different from those of healthy controls and from people with Chronic Fatigue Syndrome.4... 

Chapter 13). Failure of central control of muscle action can also have severe consequences. Malfunctioning of some parts of the central control mechanism can result in failure of muscles to contract normally and in a coordinated manner, e.g. Parkinson s disease (Chapter 14) or result in excessive fatigue (chronic fatigue syndrome (Chapter 13)). 

Chronic fatigue syndrome was first identified among nursing and medical staff at the Royal Free Hospital in London and was originally termed Royal Free Hospital syndrome or illness. In fact, it had been diagnosed two cen-... 

Although chronic fatigue syndrome is generally considered to be a recent illness, compounded by contemporary stresses particularly after a viral attack, this appears not to be the case. Edgar Jones and Simon Wesseley researched the medical literature and discovered a report of a condition resembling chronic fatigue syndrome. An extract from their paper follows. 

Edgar Jones Simon Wessely, Case of chronic fatigue syndrome after Crimean war and Indian mutiny , British Medical Journal (1999) 319, 1645-1647. 

Neuroanatomically both the locus coeruleus and the raphe nuclei project to the spinal cord where they gate sensory pathways from the skeletomuscular areas. As there is evidence that both noradrenaline and 5-HT are dysfunctional in depression, it is perhaps not surprising to find that the pain threshold is often reduced in patients with depression. Conversely, different types of antidepressants have been shown to have an antinociceptive effect in both rodent models of neuropathic pain, and clinically in fibromyalgia, chronic fatigue syndrome, postherpetic neuralgia and diabetic neuropathy. In general, it would appear that the dual action antidepressants (such as the TCAs and SNRIs) are more effective than the SSRIs. 

The idea of reduced adrenal capacity as a possible model for PTSD has also been recently raised by Heim et ah, who concluded that low cortisol may not be a unique feature of PTSD, but may represent a more universal phenomenon related to bodily disorders, having an etiology related to chronic stress (Heim et al. 2000). There are numerous stress-related disorders such as chronic fatigue syndrome, fibromyalgia, rheumatoid arthritis, chronic pain syndromes, and other disorders that are characterized by hypocortisolism. In one study, Heim et al. showed decreased cortisol responses to low-dose DEX, but failed to observe blunted ACTH responses to CRF in women with chronic pelvic pain, some of whom had PTSD, compared to women with infertility (Heim et al. 1998). Since the data were not analyzed on the basis of the subgroup with and without trauma and/or PTSD, it is not possible to directly compare results of that study to other reports examining PTSD directly. 

Unlabeled Uses Prevention of relapses of depression chronic fatigue syndrome, obsessive-compulsive disorder... 

Goodnick, P.J. and Sandoval, R. (1993) Psychotropic treatment of chronic fatigue syndrome and related disorders. / Clin Psychiatry 54 13-20. 

Jones JE Viral etiology of chronic fatigue syndrome, in Chronic Fatigue and Related Immune Deficiency Syndromes. Edited by Goodnick PJ, Khmas NG. Washington, DC, American Psychiatric Press, 1993, pp 23-43... 

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