Cytomegalic inclusion disease

Herpesviridae Cytomegalovirus Epstein-Barr virus Herpes simplex, types 1 and 2 Varicella-zoster virus Cytomegalic inclusion disease (i.e., widespread involvement of virtually any organ, especially the brain, liver, lung, kidney, intestine) Infectious mononucleosis Local infections of oral, genital, and other mucocutaneous areas systemic infections Chickenpox herpes zoster (shingles) other systemic infections... 

Christensen L, Beeman HW, Allen A. Cytomegalic inclusion disease. Arch Ophthalmol 1957 57 90. 

Smith ME. Retinal involvement in adult cytomegalic inclusion disease. Arch Ophthalmol 1964 72 44. 

The transfusion of blood and blood products carries many risks, some of which are very serious. Haemolytic reactions caused by red cell antibodies, non-haemolytic febrile reactions due to white cell antibodies, urticaria, rare but extremely severe anaphylactic reactions caused by anti-IgA in patients lacking IgA, changes of pH and electrolytes resulting from storage lesions in stored bank blood, bacterial contamination, transmission of disease (in particular hepatitis, cytomegalic inclusion disease, mononucleosis infec-tiosa, syphilis, toxoplasmosis and malaria), circulatory overload and several other complications have been discussed in SED VIII and in many recent review articles. Infection with the virus of cytomegalic inclusion disease (CMV) occurs frequently. In most people it is a benign disease. Like other viral diseases, however, it should be feared in patients with an impaired cellular immunity (1, 2CR). 

A 27- year-old male with a three-year history of AIDS complains of progressive blurring of vision for two days. Eye examination reveals evidence of retinitis consistent with cytomegalic virus inclusion disease. Intravenous treatment is started, and within five days the patient complains of muscular weakness and cramping. Blood chemistries show a creatinine of. 5.2 mEq/L and a Ca of 6.9 mEq/L. 

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