Contractors production

Drug product containers and closures specifications In-process materials Packaging material Labeling specifications Drug products specifications Procedures and specifications Batch production and control records, including Products from contractors Production records Packaging records... 

Conduct system safety engineering (analyses and incorporation of results into design, development, and operations Evaluate contractor-produced analyses and incorporation of results into contractor products Act as the technical conscience of the Agency... 

If grout and shims were used to level the machine, the machine may have to be raised so that existing grout can be removed, forms fabricated and positioned, new grout poured and left to set, and new shims sized and placed until the machine bed is as level as possible. The entire process can take days and require outside contractors production should not begin until the process is completed. 

A PHA is the initial effort in identifying hazards which singly or in combination could cause an accident or undesired event. PHA is a system-safety analysis tool used to identify hazard sources, conditions, and potential accidents (Roland and Moriarty, 1990). At the same time, PHA establishes the initial design and procedural safety requirements to eliminate or control these identified hazardous conditions. A PHA is performed in the early stages of the conceptual cycle of system development. It can be performed by engineers, contractors, production line supervisors, or safety professionals. Management must always first look at any risk involved in the operation of the system. 

The contractor is paid per foot drilled. Whilst this will provide an incentive to make hole quickly, the same risks are involved as in the turnkey contract. Footage contracts are often used for the section above the prospective reservoir where hole conditions are less crucial from an evaluation or production point of view. 

While tax and royalty fiscal systems are common, another prevalent form of fiscal system is the Production Sharing Contract, in which the investor (e.g. oil company) enters into an agreement with the host government to explore and potentially appraise and develop an area. The investor is a contractor to the host government, who retains the title of any produced hydrocarbons. 

Typically, the contractor carries the cost of exploration, appraisal and development, later claiming these costs form a tranche of the produced oil or gas ( cost oil ). If the cost oil allowance is insufficient to cover the annual costs (capex and opex), excess costs are usually deferred to the following year. After the deduction of royalty (if applicable) the remaining volume of production (called profit oil ) is then split between the contractor and the host government. The contractor will usually pay tax on the contractor s share of the profit oil. In diagrammatic form the split of production for a typical PSC is shown in Figure 13.11. 

Production levels will be influenced by external factors such as agreed production targets, market demand, the level of market demand for a particular product, agreements with contractors, and legislation. These factors are managed by planning of production rates and management of the production operation. 

The amount of land required varies as well, not only as a function of the amount of production that is anticipated, but also on the type of culture system that is used. It may take several hectares of static culture ponds to produce the same biomass of animals as one modest size raceway through which large volumes of water are constantly flowed. Constmction costs vary from one location to another. Local labor and fuel costs must be factored into the equation. The experience of contractors in building aquaculture facihties is another factor to be considered. 

Once the need for a LIMS has been justified, specifications have been written, and available vendors surveyed, the LIMS selection process begins. Each vendor s product must be evaluated for conformance to the specification and flexibiUty for future modifications. If an adequate solution is not available commercially, consideration must be given to constmcting a custom LIMS solution. This could be done in-house or by contractors. If the custom option is preferred, resources needed for future modifications and maintenance should be factored into the cost. 

Calcium carbonate is one of the most common filler/extenders used in the paint and coatings industry. Consumer and contractor paint formulas can include products from submicrometer size to coarse mesh sizes. The main function of calcium carbonate in paint is as a low cost extender. It is also used to improve brightness, appHcation properties, stabiHty, and exposure resistance. Coarse products help to lower gloss and sheen or even provide textured finishes. The selection of product type and particle size is deterrnined by the desired performance and cost of the coating. 

The actual coated fabrics themselves are not subject to these federal regulations. They are classified as "Articles of Commerce." However, in recent years most manufacturers have, for the convenience of their customers, generated an MSDS for their products. Their customers, the manufacturers, and contractors using these coated fabrics have requested this information because they are also covered under federal and state "Right to Know" laws and want to ensure the safety of their employees. 

Cut, erect, align, fit, bolt, thread or weld, and test Handle and haul, store, scaffold, lost time, tools and rentals, contractor s overhead and profit Craft rate, productivity, height, and complexity... 

Startup time may be defined as the time span between the end of construction and the beginning of normal operation. Hence it should start when the contractor finishes the whole plant or a specified section of it to enable comparisons to be made with other startup times. It is usual to define normal operation as (1) operations at a certain percentage of design capacity, (2) a specified number of days of continuous operation, or (3) the capabihiy of making products of a specified purity. 

Does contractor provide month-end balances to ABC Co. of ABC Co. owned raw materials, intermediates and finished product volumes ... 

Field labor usually runs 25% to 50% of the cost of a project. If one location has 20% lower labor productivity, the cost of the project may increase by 5% to 10%. Contractors have a good feel for the expected productivity in a given area. Such productivity adjustments are usually made with the U.S. Gulf Coast as unity. 

The confluence of sharply rising Operations and Maintenance (O M) costs. NRC requested Individual Plant Examinations (IPEs) and increased personal computer capabilities gave rise to the R R Workstation. Its uses and maintains-current PSA models and databases for individual plants to perform O M planning and scheduling, and uses the PSA in IPE models to identify plant design, procedure and operational vulnerabilities. The Risk and Reliability Workstation Alliance was organized by EPRI to support the R R Workshop in order to achieve O M cost reduction, plant productivity and safety enhancement through risk-based, user-friendly, windowed software louls (Table 3.6 8). The Alliance, initiated in 1992, includes 25 U.S. utilities and four international partners from Spain, France, Korea, and Mexico. SAIC is the prime contractor for the R R Workstation, with participation of five other PSA vendors. 

The quality of the product can only be verified by the subcontractor during its design and manufacture. (In such cases you need to rely on what the contractor tells you and to gain sufficient confidence you can impose quality system requirements, require certain design, manufacturing, inspection, and test documents to be submitted to you for approval, and carry out periodic audit and surveillance activities. This method is usually applied for one-off systems or small quantities when the stability of a long production run cannot be achieved to resolve problems.)... 

The life of the product- access to the records will probably not be needed for some considerable time, possibly long after the contract has closed. On defense contracts the contractor has to keep records for up to 20 years and for product liability purposes, in the worst case situation (taking account of appeals), you could be asked to produce records up to 17 years after you made the product. 

Even when the time comes to make a purchasing decision, an energy-efficient motor purchase is not a certainty. Sometimes an energy-efficient motor will be the economically efficient choice at other times, not. The capital investment decision is based on the cost in relation to performance, efficiency and reliability. Moreover, the decision depends on the application and the amount of time the motor is in operation. It can be the major component of a product (drill or mixer), or a minor component (computer disk drive) it can be the major component cost of a product (fan), or it can be a minor component cost (stereo tape deck) it can run almost constantly (fan, pump, and machinery), or only a few minutes a day (vacuums and power tools). For example, contractors purchase circular saws almost solely based on performance and reliability. Time is money, and since the saw is operating only a few minutes a day and the contractor is often not responsible for the electricity costs to run the motor, energy efficiency is not a consideration performance and reliability are what matter most. On the other hand, an industrial user, who runs huge electric motors twenty-four hours a day to work pumps, machinery, and ventilation equipment, is very concerned tvitli energy efficiency as well as performance and reliability. 

In practice, treatment (1) usually involves a contractor collecting a segregated batch of oil, reconditioning and returning it for re-use. A contractor can carry out the simple filtration process, but it is more usually done on-site. Re-refining is the removal of contaminants and oxidation products and previously incorporated additives to recover the lube base stock for new lubricant or other applications. 

At all times the interrelationship between budgets must be maintained - sales with finished products - products with consumption of materials - consumption of materials with labor using them, machine time and power. Machine time will influence maintenance, which will have its own content of labor, materials and work by outside specialist contractors. 

Once the performance and environmental conditions have been defined, the selection of a suitable material can be made, and this in turn can be followed, if necessary, with the necessary engineering calculations to establish strength requirements. The basic data needed for calculations have to be collected and have to pertain to the specific grade of the selected material. The pertinent information required for making determinations for longevity of the product and obtaining a general concept of the character and behavior of the selected material should be supplied by the manufacturer of the raw material and/or obtained in-house or via a contractor. 

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