Metastasis cancer

Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001 410 50-6. 

Key Words Chemokine receptor cancer metastasis migration. 

It appears that activated carbon might be a potential carrier for lymphatic delivery, or to peritoneal or pleural cavities, the most common sites in cancer metastasis. Minimal side effects are expected, since constant low concentrations of drug are maintained in the general circulation. 

Urquidi, V., Sloan, D., Kawai, K., Agarwal, D., Woodman, A. C., Tarin, D., Goodison, S. (2002). Contrasting expression of thrombospondin-1 and osteopontin correlates with absence or presence of metastatic phenotype in an isogenic model of spontaneous human breast cancer metastasis. Clin. Cancer Res. 8(1), 61-74. 

Wolman, S. R., Karyotypic progression in human tumors, Cancer Metastasis Reviews, 2 257-293 (1983). 

J. C. Byrd and R. S. Bresalier, Mucins and mucin binding proteins in colorectal cancer, Cancer Metastasis Rev., 23 (2004) 77-99. 

Fraser, A. G. Programmed cell death in C. elegans. Cancer Metastasis Rev. 18 285-294,1999. 

Fuqua SA (2001) The role of estrogen receptors in breast cancer metastasis. J Mammary Gland Biol Neoplasia 6 407... 

Inhibition of Metastasis by Protease Inhibitors. Cancer metastasis can be inhibited by either synthetic or naturally occurring protease inhibitors. Thus, various synthetic inhibitors of serine proteases have been found to prevent tumor cell invasion through amniotic membranes in vitro and to inhibit cancer metastasis in vivo [for reviews, see Aznavoorian et al. (A4) and Duffy (D6). In... 

F5. Fidler, I. J., Critical factors in the biology of human cancer metastasis Twenty-eighth G. H. A. Clowes Memorial Award Lecture. Cancer Res. 50, 6130-6138 (1990). 

J3. Jessup, J. M., and Thomas, P. C., Carcinoembryonic antigen Function in metastasis by human colorectal carcinoma. Cancer Metastasis Rev. 8, 263-280 (1989). 

L2. Liotta, L. A., Principles of molecular cell biology of cancer Cancer metastasis. In Cancer Principles and Practice of Oncology (V. DeVita, Jr., S. Heilman, S. Rosenberg, eds.), 4th ed., pp. 134-149. Lippincott, Philadelphia, 1993. 

N3. Nicolson, G. L., Cancer metastasis, organ colonization and cell surface properties of malignant cells. Biochim. Biophys. Acta 695, 113-176 (1982). 

Joseph J, Mudduluru G, Antony S, Vashistha S, Ajitkumar P, Somasundaram K (2004) Expression profiling of sodium butyrate (NaB)-treated cells Identification of regulation of genes related to cytokine signaling and cancer metastasis by NaB. Oncogene 23 6304—6315 Kao H-Y, Lee C-H, Komarov A (2002) Isolation and characterization of mammalian HDACIO A novel histone deacetylase. J Biol Chem 277 187-193... 

Since the Tc complex of (95) proved to be a powerful radiopharmaceutical for the detection of bone cancer metastasis, considerable efforts have been made to provide the reasons for the specificity. In the preparation of the corresponding radiopharmaceuticals, all three stereoisomers are present from the reaction with meso-dmsa. The reason for the osteotropic behavior may arise from deprotonation of the noncoordinated carboxylic acid groups, and the active complex in solution therefore bears a 5— charge. 

Gray-Schopfer VC, da Rocha Dias S, Marais R (2005) Cancer Metastasis Rev 24 165... 

Blobe GC, Obeid LM, Hannun YA (1994) Regulation of protein kinase C and role in cancer biology. Cancer Metastasis Rev 13 411-431... 

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