Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Chemokines and Cancer Metastasis

CXCR4 and CCR7 Receptors Play Special Roles in Cancer Metastasis [Pg.168]

As explained above, we initially found these two receptors significantly expressed in breast cancer cells. Soon many other reports documented that they were also expressed in many cancers. There are now too many reports to discuss, so I only use some examples that highlight the dominant role of these receptors. These include [Pg.168]

Retrospective Clinical Data Supports a Role for Chemokines in Cancer Metastasis [Pg.169]

The expression of CXCR4 in particular has heen reported to correlate with a worse prognosis in a wide variety of cancers [11]. This correlates with many mouse model reports where the expression of CXCR4 not only results in more abundant metastatic lesions, but also these lesions develop much faster than in tumors that do not express CXCR4. One of the outstanding questions refers to the mechanism of action of CXC R4 in these lesions. Unfortunately, the answer to this question is not likely to he simple, and it involves many aspects that are considered below. [Pg.170]

How Does the CXCR4/CXCL12 Axis Influence the Development of Metastatic Lesions  [Pg.170]

Functional Activation of Chemokine Receptors and Cancer Metastasis... [Pg.19]

Kakinuma, T. and Hwang S. T. (2006). Chemokines, chemokine receptors, and cancer metastasis. J Leukoc Biol 79(4) 639-51. [Pg.26]

Murphy PM. Chemokines and the molecular basis of cancer metastasis. N Engl J Med 2001 345 ... [Pg.736]

Cancer Metastasis and Chemokine-Chemokine Receptor System... [Pg.72]

Role of Chemokines and Their Receptors in Prostate Cancer Invasion and Metastasis... [Pg.157]

See other pages where Chemokines and Cancer Metastasis is mentioned: [Pg.643]    [Pg.167]    [Pg.168]    [Pg.170]    [Pg.172]    [Pg.174]    [Pg.643]    [Pg.167]    [Pg.168]    [Pg.170]    [Pg.172]    [Pg.174]    [Pg.7]    [Pg.18]    [Pg.158]    [Pg.308]    [Pg.459]    [Pg.169]    [Pg.268]    [Pg.10]    [Pg.47]    [Pg.336]    [Pg.341]    [Pg.344]    [Pg.302]    [Pg.379]    [Pg.387]    [Pg.387]    [Pg.654]    [Pg.1]    [Pg.9]    [Pg.10]    [Pg.18]    [Pg.21]    [Pg.23]    [Pg.27]    [Pg.31]    [Pg.63]    [Pg.64]    [Pg.68]    [Pg.68]    [Pg.71]    [Pg.73]    [Pg.73]    [Pg.98]    [Pg.104]    [Pg.109]    [Pg.110]    [Pg.113]    [Pg.114]    [Pg.153]   


SEARCH



Cancer metastasis

Chemokines cancer

Metastasis

© 2024 chempedia.info