Assessments expert

US-EPA has formed the Risk Assessment Forum, a standing committee of senior US-EPA scientists, to promote US-EPA consensus on difficult and controversial risk assessment issues and to ensure that this consensus is incorporated into appropriate US-EPA risk assessment guidance. To fulhil this purpose, the Forum assembles US-EPA risk assessment experts in a formal process to study and report on issues from a US-EPA scientific perspective. Major Fomm guidance documents are developed in accordance with the US-EPA s regulatory and policy development process and become US-EPA pohcy upon approval by the Administrator or the Deputy Administrator. The Risk Assessment Forum products include risk assessment guidelines, technical panel reports on special risk assessment issues, and peer consultation and peer review workshops addressing controversial risk assessment topics. 

Lin JH. Transporter-mediated drug interactions clinical implications and in vitro assessment. Expert Opin Drug Metab Toxicol 2007 3(1) 81—92. 

Risk assessment experts of natural and technical sciences produce the best estimate of the physical harm that a risk source may induce. 

Concern assessment experts of social sciences including economics identify and analyze the issues that individuals or society as a whole link to a certain risk. For this purpose the repertoire of the social sciences such as survey methods, focus groups, econometric analysis, macro-economic modelling, or structured hearings with stakeholders may be used. 

Mattes WB. Cross-species comparative toxicogenomics as an aid to safety assessment. Expert Opin Drug Metab Toxicol. 2006 2(6) 859-874. 

I-III studies ADRs notified to the company during clinical studies. If the product has been marketed, then all postmarketing experience should be assessed. Expert reports are not a promotion platform for the product but an assessment of the data generated, an explanation of the results and an interpretation. An expert report should not normally exceed 25 pages of A4. The expert reports should also make clear whether or not the studies submitted have been conducted according to GLP standards and whether the clinical studies have been conducted to GCP principles and in accord with the Declaration of Helsinki. A statement of the enviromental effects of the product is also necessary. 

In order to ensure the effectiveness of the assessment, overseas investment experts (with overseas investment experience) in this field are invited to score the secondary assessment indexes. For the sake of avoiding the subjective influence of various experts on the assessment result, it is required that the number of assessment experts should not be too less. It is assumed that the number of invited senior experts for overseas investment management is m and m>6. 

Marrone AK, Beland FA, Pogribny IP (2015) The role for microRNAs in drug toxicity and in safety assessment. Expert Opinion on Drug Metabolism Toxicology 11 601-611. 

Some of the material in this section was developed while the author was the Chair of the Risk Assessment Expert Committee of the Major Industrial Accidents Council of Canada... 

Unprecedented coupling between corrosion scientists, geochemists, and risk assessment experts can serve as a useful model for any high-priority thrust in corrosion. Our understanding of corrosion, welding, phase stability, and nickel-chromium-molybdenum superalloys has been advanced to levels equal to any other alloy system. While translation to practice awaits policy and political decisions, this research has led to a vast improvement in corrosion science and to technological confidence that an engineered waste barrier can be perfected to contain nuclear waste. 

At the wider level, it is crucial that safety assessment experts communicate their belief that their calculated results, although imperfect, provide sufficiently reliable input for decision makers. Numerical results of analyses extending out to geological times, if presented without sufficient discussion of their significance, lead understandably to accusations of over-optimism, immodesty or even irrationality. On the other hand, failiure to emphasise the conservative nature of safety analyses and the existence of a broad base of scientific facts which make estimates scientifically justifiable would dqprive decision makers and public of a crucial element determining their confidence in and acceptance of waste repositories. 

In this paper the intention is to review the techniques for theoretical studies which are now available and to provide some illustrations of their use based on current RARDE studies. It should be stressed that this review is carried out from the perspective of an explosives formulator or hazard assessment expert rather than that of a theoretical chemist. The aim is to challenge the theoreticians to employ the powerful techniques now at their disposal in attempts to describe the chemistry of explosives decomposition which will provide new insights to explosives formulators and novel answers to the need for higher performance, reduced hazard explosive systems. 

Much of this is also changing with international lending organizations such as the World Bank and the Interamerican Development Bank requiring environmental risk assessments to be conducted as part of the development project. Many countries now have their own local risk assessment experts and are not as dependent on outside expertise as they formerly were. One thing is sure safety does save money. Throughout this book, you can see numerous examples and sources of cost-benefit to safety. Businesses attribute this to better preventative safety management systems. 

Hadjimichael, M. 2009. A fuzzy expert system for aviation risk assessment. Expert Systems with Applications 36 6512 6519. 

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