Existing commercial chemical substances

AH of the amyl alcohols are TSCA and EINECS (European Inventory of Existing Commercial Chemical Substances) registered. 

The LD q for sodium bromide taken orally by rats is 3.5 g/kg body weight, and the TD q orally in rats is 720 mg/kg (8). RTECS Hsts data on reproductive effects in male and female rats. Sodium bromide is Hsted in the TSCA Inventory, the Canadian Domestic Substances Hst (DSL), the European Inventory of Existing Commercial Chemical Substances (EINECS), the Japanese Existing and New Chemical Substances (ENCS), and the Korean Existing Chemicals Hst (ECL). It is not regulated by the U.S. Department of Transportation. 

In the European Union, coal-derived complex chemical substances, ie, those contained in the European Inventory of Existing Commercial Chemical Substances, have been classified for carcinogenicity in the twenty-first adaptation to technical progress of the European Commission (EC) Dangerous Substances Directive 1994 67/548/EEC (57). The EC Regulation 793/93 requires data sets to be submitted by producers or importers to the... 

EINECS The European inventory of existing commercial chemical substances... 

Existing substances are substances deemed to be on the EU Market between 1 January 1971 and 18 September 1981 and listed in EINECS, the European INventory of Existing Commercial Chemical Substances (EU 2006j, ECB 2006). The substances placed on the market for the first time after this target date are new (Section 2.4.1.5). 

EINECS European Inventory of Existing Commercial Chemical Substances... 

EC (2002) European inventory of existing commercial chemical substances (EINECS). http //esis.jrc.ec.europa.eu/index. php PGM = ein. Accessed 29 Oct 2011... 

In Europe, 100,204 commercial chemical substances have been recognized and numbered under EINECS (European INventory of Existing Commercial chemical Substances) by the European Chemical Bureau (ECB) System. Another 4,381 new substances are classified under ELINCS Information System (European List of Notified Chemical Substances) since May 11, 1981. Among these. In Europe 1,230 chemical substances are officially identified as irritant or corrosive with Xi and C pictograms and risk sentences. 

The European Inventory of Existing Commercial Chemical Substances (EINECS) consists of substances on the market in the European Community between 1971 and 1981.19 These substances may be imported or manufactured without further notification. The list of 100,106 substances was published in 1990, and the contents are fixed. All chemicals that will be marketed after the September 18,1981 are not placed on the EINECS. These chemicals have to be notified before they will be placed on the market according to the sixth Amendment of Directive 67/548/EEC, Directive 79/831/EEC. Once assessed, these new chemicals are listed on the European List of New Chemical Substances (ELINCS).20 These substances must be notified by each new importer/manufacturer (although sometimes reduced notification packages may be accepted if the substance has already... 

REACH introduces a single system covering both existing and new substances under the old system and categorises substances as either non-phase-in substances (i.e. those not produced or marketed prior to the entry into force of REACH) or phase-in substances (those listed in the European Inventory of Existing Commercial chemical Substances Information System - EINECS, or those that have been manufactured in the Community, but not placed on the Community market, in the last fifteen years). 

CAS Registry Numbers are also widely used as standard identifiers for chemical substances in many of the commercial chemical inventories of governmental regulatory agencies, such as the Toxic Substances Control Act (TSCA) Inventory in the United States, the European Inventory of Existing Commercial Chemical Substances (EINECS), and the Canadian Domestic and Non-Domestic Substance Lists (DSL/NDSL). 

Existing substances are defined as those substances in use within the EU before September 1981 and listed in EINECS (European Inventory of Existing Commercial Chemical Substances). Accordingly, substances not listed in EINECS are regarded as new substances and subject to a notification procedure (Section 2.2.2). 

CHEMLIST is aregulated chemicals listing. Regulated substances listed on the Environmental Protection Agency Toxic Substances Control Act Inventory, the European Inventory of Existing Commercial Chemical Substances, and the Domestic and Nondomestic Substances List from Canada are well covered, as well as other lists of hazardous substances. More than 249,000 substances are listed. 

Not surprisingly, there are many synthetic chemicals and formulations commercially available. In Europe alone more than 100000 chemicals (not formulations) are on the European Inventory of Existing Commercial Chemical Substances (EINECS), which lists chemicals on the market before September 1981. This list differentiates between existing and all new chemicals produced since 1981 that have to be notified. During the period between 1981 and 2000 more than 2700 new substances were notified in Europe (Figure 1.3). For new substances, the obligatory notification system requires the manufacturer or importer to provide information suitable for risk assessment to be submitted to the competent authorities. The details required are dependent on the production volume or import quantities of the chemical. 

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