Quality assurance plan

Sample weight Aliquot taken Final volume 

Ca) 14 samples submitted by supervisor, with 7 samples per species (beef and poultry) fortified at least at 50 ppb for poultry and 100 ppb for beef. A blank tissue must also be included. 

Notification from Chemistry Division is required to commence official 

Intralaboratory Check Samples a. System, minimum contents. i. Frequency At least one check sample biweekly per analyst containing both cyromazine and melamine using different species. At least one out of four of these samples is to be confirmed by mass spectrometry. ii. Random replicates chosen by supervisor or Laboratory QA Officer. iii. Records to be maintained by analyst and reviewed by supervisor and Laboratory QA Officer for (a) All replicate findings. (b) Control chart on percent difference between replicates. (c) All % recoveries. b. Acceptability criteria. If unacceptable values are obtained, then i. Stop all official analyses for that analyst. ii. Investigate and identify probable cause. iii. Take corrective action. iv. Repeat Phase III of section J.3 above if cause was analyst-related. 

Sample Acceptability a. Matrix Red meat and poultry muscle and Stability 

Compliance with gas cylinder rules (with their latest amendments) and all relevant codes of design, fabrication and testing is a must. Stage inspection clause should be put in work order. Final test must be carried out in the presence of the purchaser s representative and should be as per statutory requirements. It is better to test the vessel again after installation as per standard procedures. 

IS 2825-1969 for unfired pressure vessels provides the foUowing classification 

Weld efficiency factors should be between 0.55-0.60 only. 

Full reports for dye penetration and radiography (exposed films) should be produced when asked for by purchaser. 

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Adequacy of the Quality Systems supported through Quality Assurance Plans (QAPs). in design, process, installation and servicing. 

Produce a plan that defines how an assurance of quality will be obtained, i.e. a quality assurance plan. 

Monitoring programs must have their own quality assurance programs. These may be called project quality assurance plans or protocols for specific purposes O). If reliable vendors of services are used, the bulk of the quality assurance effort can be placed on those activities unique to the program. Without reliable vendors, QA efforts will be ineffective since it is not cost effective to police quality assurance practices at all lower levels nor to screen all data for its validity. 

The program must require the vendors to measure a number of reference samples and/or duplicates submitted in a planned sequence. It should require prompt measurement and reporting of these data and should maintain the results in a control chart format. Prompt feedback and follow-up of any apparent data discrepancies and reconciliation of the results with control charts maintained by the vendors are required to minimize the length of uncertain performance. The quality assurance plan should include random sampling of the vendors data for their validity and conformance with quality assurance requirements. If quality assurance is properly practiced at all levels, an inspection of 5 percent of the total data output should be adequate. 

The program quality assurance plan may need periodic or emergency revisions Ongoing review of the data should reveal whether any deficiencies are due to Inadequate performance of vendors or to defects In the quality assurance plan Defects In the plan could result from Inadequate quality assessment techniques If measured levels of contaminants were significantly different from anticipated levels, for example ... 

Reproduced by permission from Quality Assurance Plan for Pesticide Air Monitoring , California... 

Cahfomia Air Resources Board, Quality Assurance Plan for Pesticide Monitoring, California Air Resources Board, Sacramento, CA (1999). 

Eastern Lake Survey Phase I Quality Assurance Plan... 

Ocean Data Evaluation System (ODES) Data Submissions Manual QA/QC Guidance for Sampling and Analysis of Sediments Water and Tissue for Dredged Material Evaluations Chemical Evaluations Quality Assurance Plan for the National Pesticide Survey of Drinking Water Wells Analytical Method 2, Chlorinated Pesticides Quality Assurance Project Plan for Analytical Control and Assessment Activities in the National Study of Chemical Residues in Lake Fish Tissue... 

Unlike quality assurance plans, which address primarily regulatory requirements involving comprehensive documentation, quality control programs are science based, the components of which may be defined statistically. The two most important components of quality control are (1) determination of the precision of analysis and (2) determination of the accuracy of measurement. 

B92003 Quality Assurance Plan for the National Pesticide Survey of Drinking Water Wells Analytical Method 2, Chlorinated Pesticides 810B92001 Quality Assurance Project Plan for the National Pesticide Survey of Drinking Water Wells... 

You have your methodology both verified and validated as required for measurements needing a high level of confidence. But, you must also assure that your analyst Is experienced In performing the type of analysis you need, that you have standards for the analytes available, and that you have a written quality assurance plan that documents good laboratory practice. 

Decision making Select closure alternative Establish schedule and funding profile Establish public and community communications program Develop schedule baseline Develop cost baseline and manpower estimates Develop health and safety plan Develop special technology Prepare facility closure plan Implement quality assurance plan Install special systems (e.g., CMS) Partial release of areas to EPA closure criteria learned ... 

The software design specification is written by the system supplier and must identify how the supplier intends to provide system software under a software quality assurance plan. The design specification must describe the subsystem software that will make up the computer system software and subsystem interfaces to implement the aims set out in the FDS. Each subsystem should be traceable back to statements in the FDS. 

In many instances operating system software has already been developed and is offered as a fundamental part of the computer system ready for application software to be developed or configured. In such cases it is prudent to establish the existence of the respective software quality assurance plans and procedures and the design, development, and testing records. Identification and examination of this documentation can be conducted and recorded as part of the supplier audit. (See Sec. VI.)... 

Supplier prequalification response Supplier audit report Project and quality plans Software quality assurance plan Commercial and purchasing specs. 

Commonwealth of Virginia Quality Assurance Plan for Bureau of Chemistry, July 1986. 

Establish procedures for segregating sick people from exposed but asymptomatic people at clinics. Develop quality assurance plan. 

ANSI (1989), IEEE Standard for Software Quality Assurance Plans, ANSI/IEEE Std. No. 730.1-1989, The Institute of Electrical and Electronic Engineers, New York. 

Quality measurements have several elements. Quality assurance plans and quality control procedures are an essential beginning. In addition, it is necessary to have qualified scientists whose training needs to be documented and updated on a continuous basis. Quality measurements also require proper use of reference materials where available, and laboratories must repeatedly test their ability to perform through taking part in proficiency testing schemes. The provision of another essential element in quality measurements, namely validated methods, is the primary contribution from the work of AOAC. 

An important part of a quality assurance plan includes the external validation of sweat analysis accuracy through participation in proficiency testing. The CAP offers a proficiency testing program consisting of six specimens per year. Participants receive feedback concerning their performance on these specimens relative to others in their peer group. 

NADP Quality Assurance Plan for Deposition Monitoring", National Atmospheric Deposition Program, 1984. 

Pre-shipment inspection can be performed along with vendor audits to address issues such as software development and quality assurance plans, operational reports, and specific vendor/purchaser inspection reports. 

National Surface Water Survey Western Lake Survey (Phase 1, Synoptic Chemistry) Quality Assurance Plan... 

Before the equipment is delivered to the site it will normally undergo the type and routine tests in the factory. These tests are often referred to as the factory acceptance tests (FAT). Some documents are required before the FAT and others afterwards. Those required before are usually the inspection reports as part of the quality assurance plan, instruction manuals for transportation, storage, installation and commissioning routine maintenance. 

The next fonr chapters are devoted to various aspects of data interpretation, data presentation, and quahty assurance. Chapter 9 considers interpretation of data for radionuchde identification by decay scheme. Chapter 10 reviews the important topics of data calculation, measurement uncertainty, data evaluation, and reporting the results. Chapter 11 describes the quality assurance plan that must govern all laboratory operations. Chapter 12 discusses methods diagnostics to correct the analytical and measurement problems that can be expected to plague every laboratory. 

Erroneous values have a way of creeping into results despite the control measures in the Quality Assurance Plan (QAP). The data review process must be designed to remove such mistakes. Data review should accompany each step of the analytical process from sample receipt to calculation of activity. Thereafter, weeding out erroneous values becomes a management responsibility during data compilation for presentation andretention. Especially for the reality checks described below, the data compiler must be knowledgeable about radioanalytical chemistry processes as well as the pattern of analytical results related to sources of radionuclides, or must be assisted by specialists in these topics. 

As these QA measures became more pervasive and intricate, their formal organization as a quality assurance plan (QAP) was deemed necessary. Every laboratory should prepare a QAP that meets all the requirements stated by its operating license, its nuclear materials license (see Section 13.8.2), and all local, state, and federal regulations. In addition, the laboratory must prepare a QAP suitable for each customer who may have different format preferences or requirements. 

A radioanalytical chemistry laboratory requires a Radiation Safety Manual (RSM) or Radiation Protection Plan (RPP) in addition to a Quality Assurance Plan (QAP). The format is controlled by the licensing agency for the facility the Nuclear Regulatory Commission (NRC) requires the RSM, while the Department of Energy (DOE) requires the RPP. These plans are stand-alone documents that deal specifically with radiation safety issues and practices to set safe operating parameters in the laboratory. 

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