Essential element

Table 1. Chemical Elements Essential to Healthy Growth of Plants ...

An inventor may estabHsh utiHty by providing several working examples which disclose preparation, appHcation, and even some or all of the benefits of the invention. UtiHty may also be substantiated by merely disclosing several appHcations for the invention. One method of determining the breadth or scope of an invention is to define the invention by only those elements essential to performing the intended task. This definition should then become the broadest cl aim of the patent appHcation. 

Cobalt is one of twenty-seven known elements essential to humans (28) (see Mineral NUTRIENTS). It is an integral part of the cyanocobalamin [68-19-9] molecule, ie, vitamin B 2> only documented biochemically active cobalt component in humans (29,30) (see Vitamins, VITAMIN Vitamin B 2 is not synthesized by animals or higher plants, rather the primary source is bacterial flora in the digestive system of sheep and cattle (8). Except for humans, nonmminants do not appear to requite cobalt. Humans have between 2 and 5 mg of vitamin B22, and deficiency results in the development of pernicious anemia. The wasting disease in sheep and cattle is known as bush sickness in New Zealand, salt sickness in Florida, pine sickness in Scotland, and coast disease in AustraUa. These are essentially the same symptomatically, and are caused by cobalt deficiency. Symptoms include initial lack of appetite followed by scaliness of skin, lack of coordination, loss of flesh, pale mucous membranes, and retarded growth. The total laboratory synthesis of vitamin B 2 was completed in 65—70 steps over a period of eleven years (31). The complex stmcture was reported by Dorothy Crowfoot-Hodgkin in 1961 (32) for which she was awarded a Nobel prize in 1964. 

Perhaps, first of all, we must know that our food is nutritious, that it contains the elements essential to growth and maintenance of our bodies in optimum amount along with the calories needed for the fuel supply. As our living habits become more complex, we are increasingly dependent on precise analysis because the naturally balanced diet of our ancestors is no longer to be had by most of us. 

Oxygen A gaseous element essential to human life comprises about 20% of the air... 

P Phosphorous Combined with other elements in nature another element essential to life... 

The following references present work relevant to this manuscript that have been published since the time of submission. For a description on the embryonic developmental expression of DDC, TH, serotonin and dopamine see Lundell and Hirsh, 1994. For a more detailed examination of elements essential in the alternative splicing of Ddc see Shen et al., 1993 and Shen and Hirsh, 1994. For additional work on the use of gene transfection in the treatment of Parkinson s disease see Kang et al., 1993. 

Ecologically, copper is a trace element essential to many plants and animals. However, high levels of copper in soil can be directly toxic to certain soil microorganisms and can disrupt important microbial processes in soil, such as nitrogen and phosphorus cycling. Copper is typically found in the environment as a solid metal in soils and soil sediment in surface water. There is no evidence that biotransformation processes have a significant bearing on the fate and transport of copper in water. 

Some such starts were undoubtedly abiotic but the main paths only became firmly established in reproductive organisms. These pathways are set out in detail in wall charts and in all biochemical textbooks, but they usually omit the inorganic elements essential to all pathways. The primitive pathways to nucleic acids involved the synthesis of phosphorylated sugars and we envisage the bases as starting from HCN and NH3... 

Thirdly, some obvious applications of coordination chemistry are omitted from this volume if they are better treated elsewhere. This is the case when a specific application is heavily associated with one particular element or group of elements, to the extent that the application is more appropriately discussed in the section on that element. Essentially all of the coordination chemistry of technetium, for example, relates to its use in radioimmunoimaging inclusion of this in Chapter 20 of this volume would have left the chapter on technetium in Volume 5 almost empty. For the same reason, the applications of actinide coordination complexes to purification, recovery,... 

Chemical elements essential to life forms can be broken down into four major categories (1) bulk elements (H, C, N, O, P, S) (2) macrominerals and ions (Na, K, Mg, Ca, Cl, PO4A SC>4 ) (3) trace elements (Fe, Zn, Cu) and (4) ultratrace elements, comprised of nonmetals (F, I, Se, Si, As, B) and metals (Mn, Mo, Co, Cr, V, Ni, Cd, Sn, Pb, Li). The identities of essential elements are based on historical work and that done by Klaus Schwarz in the 1970s.1 Other essential elements may be present in various biological species. Essentiality has been defined by certain... 

Inorganic or metal-containing medicinal compounds may contain either (a) chemical elements essential to life forms—iron salts used in the treatment of anemia—or (b) nonessential/toxic elements that carry out specific medicinal purposes—platinum-containing compounds as antitumor agents or technetium... 

Mossessova, E. and Lima, C. D. Ulpl-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast. Mol. Cell 2000, 5, 865-76. 

All of the data in Fig 7.5 were analyzed using linear regression. The summation of the helix and core-regressed flow rates are plotted in Fig. 7.5 as the red dotted line. The experimental superposition for the flows induced by the screw elements essentially overlaid the regression line for the screw configuration rate. Thus, it was concluded that the helix is the pump in the single-screw extruder, and core rotation reduces the flow by dragging the fluid back toward the extruder inlet. 

Hydrogen fusion via either the proton-proton chain or the CNO cycle in the centre of stars comes to an end when most of the hydrogen has been transformed into helium. Helium fusion produces two elements essential to life, namely carbon and oxygen. In fact, carbon constitutes 18% of our bodies, and oxygen 65%, whilst the fractions of these same elements in solar material are just 0.39% and 0.85%, respectively. Only hydrogen and helium are more abundant in the Sun. 

The elements essential for life can be divided into macroelements (daily requirement > 100 mg) and microelements (daily requirement < 100 mg). The macroelements include the electrolytes sodium (Na), potassium (K), calcium (Ca), and magnesium (Mg), and the nonmetals chlorine (Cl), phosphorus (P), sulfur (S), and iodine (I). 

FIGURE 1-12 Elements essential to animal life and health. Bulk elements (shaded orange) are structural components of cells and tissues and are required in the diet in gram quantities daily. For trace elements (shaded bright yellow), the requirements are much smaller for humans, a few milligrams per day of Fe, Cu, and Zn, even less of the others. The elemental requirements for plants and microorganisms are similar to those shown here the ways in which they acquire these elements vary. 

Selenium is a trace element essential to life. For example, the selenium-containing enzyme glutathione peroxidase catalyzes the destruction of peroxides (ROOH) that are harmful to cells. Conversely, at high concentration, selenium can be toxic. 

Nonmetallic elements predominating in the ash are phosphorus (700 g in the human body), sulfur (175 g), and chlorine (105 g). Not only are these three elements essential to all living cells but also selenium, fluorine, silicon (Box 4-B), iodine, and boron are needed by higher animals and boron by plants (Fig. 1-17). Iodine deficiency may affect one billion human beings and may cause 20 million cases per year of cretinism, or less severe brain damage.158... 

System Crystallographic elements Essential symmetry Number of point groups... 

TRACE ELEMENT (Mlcronutrient). An element essential to plant and animal nutrition in trace concentration, i.e., minute fractions of 1% (1000 ppm or less). Plants requite iron, copper, boron, zinc, manganese, potassium, molybdenum, sodium, and chlorine. Animals require iron, copper, manganese, cobalt, selenium, and potassium. Such elements are also called micronutrients. Do not confuse with tracer. 

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