Damage oxidative

In addition to oxidation itself, gas diffusion into the base metal can be more damaging than the actual loss of metal from the surface. Thus the loss in mechanical properties owing to diffusion of oxygen into niobium makes it more difficult to protect niobium against oxidation damage than molybdenum, even though molybdenum has less resistance to normal oxidation effects than niobium. 

Vayalil PK, Mittal A, Kara Y, Elmets CA, Katiyar SK (2004) Green tea polyphenols prevent ultraviolet light-induced oxidative damage and matrix metal-loproteinases expression in mouse skin. J Invest Dermatol 122 1480-1487... 

As mentioned earlier, cancerous mutations can occur as a result of oxidative damage to DNA caused by free radicals generated as a damaging side-effect... 

Lee et al., 2001 Murine osteoblastic MC3T3 cells Genistein at physiological concentrations stimulates cell proliferation and prevents oxidative damage. 

LEE Y-s, CHEN X and ANDERSON J B (2001) Physiological concentrations of genistein stimulate the proliferation and protect against free radical-induced oxidative damage of MC3T3-E1 osteobast-like Nutr Res 21, 1287-98. 

As a species that has evolved in such an aggressive environment we have developed mechanisms that both defend against oxidative damage and can undertake damage repair. Free radical generation in vivo has even been adopted as a mechanism to protect against physical, chemical and biological injury. 

PORRiNi M and Riso P (2000) Lymphocyte lycopene concentration and DNA protection from oxidative damage is increased in women after a short period of tomato consumption. JNutr 130(2) 189-92. 

Both thermodynamic and kinetic factors are of importance for antioxidant capacity. The antioxidant has to be located in the right position at the right time in order to prevent oxidative damage to vital cell components and will need to be regenerated from the one-electron oxidised form in a recycling process ... 

Protection against oxidative damage of erythrocyte membrane by the flavonoid quercetin and its relation to iron chelating activity, FEBS Letters, 416, 123-9. 

Lafferty, J., Truscott, T.C., and Land, E.J., Electron transfer reactions involving chlorophylls a and b and carotenoids, J. Chem. Soc. Farad. Trans., lA, 2760, 1978. Burri, B.J., Clifford, A.J., and Dixon, Z.R., Beta-carotene depletion and oxidative damage in women, in Natural Antioxidants and Anticarcinogens in Nutrition, Health and Disease, Kumulainen, J.T. and Salonen, J.T., Eds., Royal Society of Chemistry, Stockholm, 1999, 231. 

---