Menthol ointments

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Inunctions Inunctions are ointments applied with friction, intended for local application and quick absorption. The term was formerly applied to preparations consisting of wool fat in which mercury or other medicinal agents were incorporated. A Compound Menthol Inunction (retitled Compound Menthol Ointment in 1936) remained official in the National Formulary until 1960. ... 

Camphor, eucalyptus oil, and menthol ointment contains camphor 5.2%, eucalpytus oil 1.2%, and menthol 2.8%. Inactive ingredients are carbomer 954, cedar leaf oil, cetyl alcohol, cetyl palmitate, cyclomethicone copolyol, dimethicone copolyol, dimethicone, ethylene diamine... 

Menthol, also known as peppermint oil, is used widely in toothpastes, mouthwashes, gum, sore-throat lozenges, lip balms, and nasal decongestants. For topical analgesic use, it is available in creams, lotions, ointment, and patches. The patches can be trimmed to fit the affected area. 

Rx Testosterone-menthol eutectic ointment (2% testosterone) (100 g) Testosterone-menthol eutectic mixture 6.33 g Hydrophilic petrolatum 93.67 g... 

Monoterpenes, 10-carbon-containing terpenoids, are composed of two isoprene units, and found abundantly in plants, e.g. (+)-limonene from lemon oil, and (—)-linalool from rose oil. Many monoterpenes are the constituents of plant volatile oils or essential oils. These compounds are particularly important as flavouring agents in pharmaceutical, confectionery and perfume products. However, a number of monoterpenes show various types of bioactivity and are used in medicinal preparations. For example, camphor is used in liniments against rheumatic pain, menthol is used in ointments and liniments as a remedy against itching, bitter-orange peel is used as an aromatic bitter tonic and as a remedy for poor appetite and thymol and carvacrol are used in bactericidal preparations. 

S. K. Pant, P. N. Gupta, K. M. Thomas, B. K. Maitin, and C. L. Jain, Simultaneous determination of camphor, menthol, methyl salicylate, and thymol in analgesic ointments by gas-liquid chromatography, LC-GC, 8 322. 

Ointments Capreomycin sulfate GC Disperse in CHC13, 50°C, filtered, ISTD added 1,95% OV-210-1.5% OV-17, Supelco 130°C FID Resolved from menthol, methyl salicylate and thymol 10-campho-rsulphonic acid, HPLC [384] [378]... 

Toxicity. The minimum lethal dose has been estimated to be about 2 g. The application of drops or ointments containing menthol to the nostrils of infants is dangerous and may cause instant collapse. Ingestion of excess menthol may cause severe abdominal pain and coma. 

Menthol is largely used as a flavoring or olfactory agent in a variety of products, including cigarettes, liqueurs, cough drops, mouthwashes, toothpastes, and shampoos. Menthol has been used in different medications to relieve symptoms of asthma and rhinitis and is a constituent of cold remedies and ointments designed to be rubbed on to the chest or applied around and even into the nostrils. Applied to the skin, it acts as a rubefacient and counter-irritant, but substantial concentrations of volatile oil can be inhaled from the skin. 

Menthol is a white, waxy crystalline compound having a strong odor of peppermint. Its main source is oil of peppermint from the plant, Mentha arvensis. It is an ingredient of decongestant ointments and nasal sprays and is also used to flavour toothpaste and cigarettes. 

As outlined when discussing absorption bases, the drug may also be dissolved in water to form a solution to be levigated into an ointment base or cream. Such addition softens creams even to the point of converting them to thick lotions. The chosen vehicle, of course, must have an inherent capacity to emulsify or otherwise take up the solution. Aromatic materials such as essential oils, perfume oils, camphor, and menthol, which volatilize if added when the base is hot, are incorporated into these semisolids while they are stiU being mixed but near the temperature where a particular system starts to congeal. Volatile materials are often introduced into the formulation as hydroalcoholic solutions. 

Commercially available common cold preparations may contain Menthol, Camphor, Turpentine, Clove oil. Thymol, Eucalyptus oil, yellow soft paraffin oil, and that essential oils that evaporate at the tempera-tme of the human body. When the ointment is rubbed on the skin, a local stimulation of the peripheral blood vessels is obtained,... 

Menthol, Methyl Salicylate, and Menthol Cream and Ointment... 

This cream and ointment contain menthol in an alcohol base gel, combinations of methyl salicylate, and menthol in cream and ointment bases, as well as a combination of methyl salicylate, menthol, and camphor in a nongreasy cream base all are suitable for topical application. The varieties include the ointment (methyl salicylate, 18.3% ... 

Benzocaine (ethyl p-aminobenzoate) is used topically by itself or in combination with menthol or phenol in nonprescription dosage forms such as gels, creams, ointments, lotions, aerosols, and lozenges to relieve pain or irritation caused by such conditions as sunburn, insect bites, toothache, teething, cold sores or canker sores in or around the mouth, and fever blisters. Benzocaine is a lipophilic local anesthetic agent with a short duration of action. 

Calnan CD (1975) Sensitivity to benzamine lactate. Contact Dermatitis 1 56 Calnan CD (1978) Oxypolyethoxydodecane in an ointment. Contact Dermatitis 4 168 Calnan CD (1979) Allergy to idoxuridine ointment. Contact Dermatitis 5 194-195 Calnan CD (1980) Allergy to the local anaesthetic diperodon. Contact Dermatitis 6 367 Calnan CD, Harmon RRM, Wells GC (1961) Photodermatitis from soap. Br Med J 2 1266 Camarasa G (1976) Contact dermatitis from mercurochrome. Contact Dermatitis 2 120 Camarasa G, Alomar A (1978) Menthol dermatitis from cigarettes. Contact Dermatitis 4 169... 

Nasal sticks and so called inhalation ointments with volatile ingredients such as menthol and eucalyptol are mainly used in self-care. The same is true for vapours. 

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