National Formulary

These white oils are subject to specifications from various organizations Codex in France, British Pharmacopoeia" (BP) in the United Kingdom, and National Formulary (NF) in the USA. 

U.S. Pharmacopeia XX, (USP XX-NF XV), The United States Pharmacopeial Convention Inc., Rockville, Md., 1980 National Formulary XIW, Amehcan Pharmaceutical Association, Washington, D.C., 1975. 

Specifications and Analysis. R%-MaHc acid that is sold in the United States meets the specifications of the Food Chemicals Codex and National Formulary, which are Hsted in Table 5 (40,41). MaHc acid is available in the following U.S. standard sieve sizes ... 

Parameter or substance Food Chemicals Codex National Formulary... 

Sorbic acid is produced and marketed in the United States in the dust-free powder form. The 1995 tmckload (TL) Hst price was U.S. 8.60— 8.80/kg for food grade and 12.41/kg for National Formulary (NF) grade. Water-soluble potassium sorbate is marketed as a powder or as granules. The 1995 TL Hst price was U.S. 7.90— 8.15/kg for food grade and 11.75/kg for NF grade. In addition to Eastman, the only U.S. producer, there are four Japanese producers and two producers in the European Union. Worldwide consumption in 1994 was approximately 2700—3000 metric tons and the nameplate productive capacity was approximately 2900—3100 metric tons. 

Table 4. National Formulary And Food Chemicals Codex Specifications...

Grades are T = technical, SQ = special quality, NF = National Formulary and Ph = photo. 

Arecoline is usually stated to be present to the extent of 0-1 per cent., but Chemnitius gives the yield of hydrobromide as 0-35 to 0-4 per cent. Arecaidine and guvacine occur in smaller quantities, whilst guvacoline and arecolidine are found only in minute amounts. Alkaloidal assay processes for areca nuts have been published by Bourcet, and the National Formulary Committee, and Bond has described a method of estimation for arecoline hydrobromide. A microchemical test for the identification of arecoline has been devised by Gornyi. ... 

Name listed in The United Sates Pharmacopeia-National Formulary may be the same as the generic name. 

For further information, see the current issue of the British National Formulary. 

British National Formulary. London British Medical Association The Pharmaceutical Press. (The chapter on drugs used in the treatment of infections is a particularly useful section. New editions of the BNF appear at regular intervals.)... 

Chlorine and iodine have been used extensively since their introduction as disinfecting agents in the early 19th century. Preparations containing these halogens such as Dakin s solution and tincture of iodine were early inclusions in many pharmacopoeiae and national formularies. More recent formulations of these elemens have improved activity, stability and ease of use. 

Implants are small, sterile cylinders of dmg, inserted beneath the skin or into muscle hssue to provide slow absorption and prolonged achon therapy. This is principally based on the fact that such dmgs, invariably hormones, are almost insoluble in water and yet the implant provides a rate of dissoluhon sufficient for a therapeuhc effect. The British Pharmacopoeia (1993) describes one implant, testosterone. The United States National Formulary (1990) also ineludes oestradiol. Implants are made fiom the pure drug into tablet form by compression or fusion. No other ingredient can be included sinee this may be insoluble or toxie or, most importantly, may influence the rate of drug release. 

The current British Pharmacopoeia and British National Formulary should be consulted for further information, including toxic manifestations. 

U.S. Pharmacopeia National Formulary. (1995) U.S. Pharmacopoeia Convention Inc., Rockville, MD. 

The 2000 U.S. Pharmacopoeia and National Formulary, USP 24-NF 19, was published in October 1999. It became official on 01.01.2000. USP-NF is one of, if not the most, widely recognized of the world s pharmacopoeial compendia of standards for drug strength, quality, purity, packaging, labelling and storage. USP-NF also provides standards for devices and diagnostics, as well as nutritional supplements. 

A statement of each method used in the testing of the sample. The statement shall indicate the location of data that establish that the methods used in the testing of the sample meet proper standards of accuracy and reliability as applied to the product tested. (If the method employed is in the current revision of the United States Pharmacopeia, National Formulary, Association of Official Analytical Chemists, Book of Methods, or in other recognized standard references, or is detailed in an approved new drug application and the referenced method is not modified, a statement indicating the method and reference will suffice). The suitability of all testing methods used shall be verified under actual conditions of use. 

The first official injection (morphine) appeared in the British Pharmacopoeia (BP) of 1867. It was not until 1898 when cocaine was added to the BP that sterilization was attempted. In this country, the first official injections may be found in the National Formulary (NF), published in 1926. Monographs were included for seven sterile glass-sealed ampoules. The NF and the United States Pharmacopeia (USP) published chapters on sterilization as early as 1916, but no monographs for ampoules appeared in USP until 1942. The current USP contains monographs for over 500 injectable products [1]. 

The United States Pharmacopeia 24 (USP)/77ie National Formulary 1, U.S. Pharmacopeial Convention, Rockville, MD, 1999, pp. 2113-2114. 

USP24. <601 > Aerosols, Metered Dose Inhalers, and Dry Powder Inhalers. The United States Pharmacopoeia and National Formulary 1895-1912, 2000. 

Trade associations and the compendia also played an important role in drug product control and quality during the nineteenth and twentieth centuries. The United States Pharmacopeia (USP) and National Formulary (NF) established standards of potency and... 

United States Pharmacopeial Convention, Fourth Supplement of the United States Pharmacopeia— National Formulary, United States Pharmacopeial Convention, Rockville, MD, 1988, pp. 2249-2250. 

In the early 1900s, the U.S. Pharmacopeia, National Formulary had excellent quality control guidelines and safe dosages for hundreds of herbs [25]. Products that are labeled as conforming to the U.S. Pharmacopeia (USP) or National Formulary (NF) standards should be recommended whenever possible. A product labeled as USP indicates that the active ingredient has been approved by the FDA or, alternately, that the use has been accepted by the USP. If the label contains the NF designation, the product has been neither approved by... 

USP 23-NF18 (1995) The US pharmacopoeia the national formulary. US Pharmacopeial Convention Inc, Rockville, MD... 

National Formulary, 14th Ed., American Pharmaceutical Association, Washington, DC, p. 145 (1975). 

Anon. National Formulary XIV page 308, 1975 Published by American Pharmaceutical Association. 

National Environmental Policy Act (NEPA), 10 228 21 590 National Fire Protection Association (NFPA), 15 767 24 284 National Formulary, 18 701 National Highway Traffic Safety... 

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