Focus on safety

To evaluate a job effectively, you should have some experience and be trained in the intended purpose of the JHA, have an open mind, and have examples of correct methods. Focusing on safety is essential to the job being evaluated. 

Sobel JD. Use of antifungal drugs in pregnancy a focus on safety. Drug Saf 2000 1 77-85. 

For two decades, the Ethyl Corporation had controlled the worldwide market for the tetraethyl lead additive discovered by Thomas Midgley, Jr. (Chapter 6). Ethyl s 2 million annual advertising budget identified tetraethyl lead with baseball, football, and the American Way of Life. The company funded almost all the research about tetraethyl lead s effect on human health. As a result, research on tetraethyl lead had focused on safety in the factory workplace rather than on the health of the general population. 

SPI s Polyurethane Division has an active Product Stewardship Issues Group, which has made available a variety of education materials and workshops. Emphasis has been placed on the educational materials, group s stewardship philosophy, focusing on safety and health issues and the literature available. Some examples of the literature available are listed. 

Management focuses on safety-oriented programs to prevent business interruptions. 

While the above examples focus on safety matters associated with pharmacological off-targets, it has to be emphasized that the knowledge of physicochemical properties of compounds is equally important at any phase of drug discovery. For example, poor solubility and permeability can prevent decent exposure and extensive hepatic metabolism might create inactive or toxic metabolites. 

FMEA is focused on safety consequences of component failures. Identified failure modes of a component are analyzed case by case. The analysis process results in an explicit and documented decisions that take into account the risk associated with a given failure mode. The decision can be just the acceptance (supported by a convincing justification) of the consequences of the failure or it can suggest necessary design changes to remove (or mitigate) the consequences or causes of the failures. Documentation is an important output of FMEA. This documentation can be then referred to by a safety case for the considered system. 

We have a program at Phillips, for folks who come into the plant, yard men included—folks who dig the holes and turn the wrenches. It has a focus on safety, and it is a peer mentoring program, but it is voluntary and seems to work fairly well. The structured formal programs with mentor assignments were not so successful some programs worked and some didn t. 

Greater focus on safety over the life cycle of chemicals... 

Selection in this chapter is strictly focused on safety related data in the field of explosion protection, neglecting all the other aspects like maintenance or financial considerations (this will be the objective of Chapter 9). Here, selection means the appropriate choice of electrical apparatus according to temperature class and MESG or MIC/MIC (CH4) grouping, taking into account the combustible raw materials and products in the relevant plant. 

Beutner and co-workers developed a practical and efficient 4-hydroxyquinolinone esters and amides that focuses on safety The desired 4-hydroxyquinolinone esters 94 were synthesized from substituted isatoic anhydrides 95. This chemistry was without the need for chromatography. 

Moureau, N. Vascular access with a focus on safety. Infusion 1999, 6, 16-26. 

Roberts HR. Clinical experience with activated factor VII focus on safety aspects. Blood Coagul Fibrinolysis 1998 9(Suppl 1) S115-18. 

Laboratory work must be conducted with the realization that safe operation is only achieved by constant focus on safety. The point is not to be afraid, but to be aware of potential hazards and responsible for one s behavior. Hazard identification is crucial for accident prevention. Adverse effects can be avoided when both the manager and the worker make safety a priority. This section identifies the primary hazards in the radioanalytical chemistry laboratory, and ways to minimize the possibility of accidents. 

It can be suggested that a consequence of this focus on Brand Zero has produced a depersonalisation of health and safety management. Within a project or organisational context, one individual alone is not able to prevent all accidents it requires shared practice if only because of the logistical and physical demands of the site. Yet under Brand Zero, this shared focus can be easily affected by others, and so responsibility for success resides within the shared workplace, which in turn can lead to individual disassociation with health and safety management at a personal level. Just one incident can therefore ruin the figures and potentially disenchant those who should still be focused on safety management in practice. 

So far the discussion has focused on safety versus reliability at the physical level. But what about the social and organizational levels above the physical system Are safety and reliability the same here as implied by High Reliability Organization (HRO) advocates who suggest that High Reliability Organizations (HROs) will be safe The answer, again, is no [124]. 

The definition of the word incident covers not just safety and environmental harm but also economic loss. Most of the literature to do with incident investigation and analysis focuses on safety-related events. But there is no reason why the techniques developed to investigate and understand such events could not also be used to address lost production, reduced efficiency, and unexpected equipment failure. 

When the activity is carried out in a lesson the risks involved can be discussed with the pupils and their responses used to help them understand why, for safety reasons, it is important to follow a particular procedure and the measures that can be taken to control risk. Such discussions, ways to keep safe, as part of a lesson will also help to develop pupils life skills and understanding of risks in general. Pupils ideas can also be used each time a lesson focusing on safety awareness is taught. Discussions could focus on ... 

Much has been written about subgroup analysis for efficacy assessment (e.gv Yusuf et al., 1991 Assmann et al., 2000 Cui ef al., 2002 Li et al., 2007 Wittes, 2009 Lipkovich et al., 2011). Many of the analytical issues related to efficacy subgroup analysis are applicable to subgroup analysis for safety. In this chapter, we will follow the definition adopted by Yusuf et al. (1991) who defined subgroup as a group of patients characterized by a common set of paramefers prior to treatment initiation. In clinical trials, we refer to those characteristics as characteristics at baseline. Also, we focus on safety experience as reflected by adverse events, laboratory measurements, x-ray, ECG, etc. As a general rule, we do not include lack (f efficacy as an adverse event in this chapter. 

In addition to interaction between technical specialists, it was further noted the need for training and educational programs to achieve these objectives. It was also recommended that follow-up efforts should focus on safety management and safety technology development for weapons-related nuclear materials (exclusive of nuclear reactors, weapons dismantlement, waste disposal and other areas in which Memoranda of Cooperation exist between DOE and Minatom). However, it was further recognized that technical exchanges in the area of nuclear materials safety might benefit from a Memorandum of Cooperation between DOE and Minatom in this area and that efforts should be directed towards this accomplishment. 

Week M, Reinartz T (1999) Untersuchungen von werkzeug- und spannsystemen unter sicherheit-stechnischen gesichtspunkten [investigations on tool and tool-clamping systems with focus on safety]. Institut fiir Arbeitswissenschaft, Kassel (in German)... 

---