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Drug selection

Muronomab-CD3 is a murine monoclonal antibody directed against the CD3 complex of the T-lymphocyte antigen receptor. This drug selectively diminishes the T-lymphocyte pool resulting in a strong lymphopenia. Similar to other nonhuman antibodies the generation of human antimurine antibodies (HAMA) limits its long-term use. [Pg.619]

Selective serotonine reuptake inhibitor (SSRI) is an abbreviation for the class of antidepressants known as the Selective Serotonin Reuptake Inhibitors. Examples of SSRIs include fluoxetine, paroxetine, citalopram, and sertraline. These drugs selectively inhibit the serotonin transporter thus prolonging the synaptic lifespan of the neurotransmitter serotonin. [Pg.1113]

The NSAIDs have a variety of uses that vary depending on the drug selected. NSAIDs are used for the following conditions ... [Pg.162]

Stockfisch TP. Partially unified multiple property recursive partitioning (PUMP-RP) a new method for predicting and understanding drug selectivity. J Chem Inf Comput Sci 2003 43 1608-13. [Pg.373]

The Cadila system [13] has been designed to formulate tablets for drugs based on their physical (solubility, hydroscopicity, etc), chemical (functional groups), and biologically interrelated (dissolution rate) properties. The system first identifies the desirable properties for optimum compatibility with the drug, selects those excipients that have the required properties, and then recommends proportions based on the assumption that all tablet formulations comprise at least one binder, one disintegrant, and one lubricant. Other... [Pg.684]

Halliwell, B. (1991). Drug antioxidant eflfects. A basis for drug selection Drugs 42, 469-605. [Pg.110]

Contreras et al., in press) indicate that PCP binding sites and sigma opioid sites may be distinct due to differences in drug selectivity and regional distribution. [Pg.39]

Drug selection for the management of patients with hypertension should be considered as adjunctive to nonpharmacologic approaches for blood pressure lowering, and ultimately the attainment of target blood pressure in many cases maybe more important than the antihypertensive agent used. [Pg.9]

Determine if any drugs need to be discontinued, or alternate drugs selected, to prevent worsening of renal function. [Pg.372]

Once the organism has been identified and sensitivities are known, drug selection should be adjusted to reflect the susceptibilities of the organism. Streptococcal, staphylococcal, and enterococcal species sensitive to P-lactam antibiotics should be treated with continuous IP dosing to increase efficacy and minimize resistance.49 Peritonitis caused by S. aureus or P. aeruginosa are often associated with catheter-related... [Pg.399]

Recommend treatment (including drug selection, dosing, monitoring, and alternative treatments) for group B Streptococcus based on guidelines of the Centers for Disease Control and Prevention. [Pg.721]

Identify factors that guide drug selection for an individual patient. [Pg.803]

Recommend an approach to drug selection in patients with multiple drug allergies. [Pg.819]

Develop a pharmacotherapeutic plan for a patient with acute gouty arthritis or uric acid nephropathy that includes individualized drug selection and monitoring for efficacy and safety. [Pg.891]

Gather patient history. Assess factors involved in drug selection. Inquire about social history and alcohol use. Ask the patient about drug allergies and chronic health problems such as asthma. [Pg.908]

Duration of therapy, like drug selection, depends on patient age and disease severity. Standard 10-day oral therapy is more effective than shorter courses for uncomplicated AOM in children younger than 2 years of age and those with recurrent infections, as well as in older patients with severe illness.5,24 Exceptions to the 10-day regimen are for azithromycin and ceftriaxone. In older children with mild or moderate illness, antibiotic therapy is needed only for 5 to 7 days. [Pg.1065]

Review the dosages of all medications to be sure that they are appropriate for age, weight, and major organ function. Verifiy that the drugs selected are not contraindicated in the patient with allergies or other intolerances. [Pg.1137]


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Anticancer drugs selective toxicity

Antihypertensive drugs selection

Antiinflammatory drugs, nonsteroidal selection

Antimicrobial agents/drugs selection

Antiparasitic drugs selective toxicity

Antipsychotic drugs selective serotonin reuptake inhibitors with

Antitumor drugs selective toxicity

Application of the Methodology to Selected Drugs

Beta-blocking drugs selectivity

Bioavailability testing drug product selection

Biopharmaceutics candidate drug selection

Bioreductive drug selectivity

COX-2-selective nonsteroidal anti-inflammatory drugs

Candidate drug salt selection

Candidate drug selection biopharmaceutical support

Candidate drug selection lead identification

Candidate drug selection preformulation

Candidate drug selection, preferred

Chemical formulas selected drugs

Cleaning Dirty Drugs with Selectivity Filters Basic Insights

Compound selection drug properties

Developing countries drug selection

Drug action selectivity

Drug candidate selection

Drug delivery intestine-selective

Drug delivery kidney-selective

Drug delivery selective

Drug delivery selectivity

Drug delivery site-selective

Drug delivery systems vehicle selection

Drug delivery tumor-selective

Drug design lead’ structure selection

Drug discovery stages candidate selection

Drug products, formulation development excipient selection

Drug products, formulation development state selection

Drug selection genomics

Drug selective electrode

Drug target selection

Drug validation methods selection

Drugs dose selection

Drugs, chiral selected single compounds

Elimination half life selected drugs

Formulary systems drug selection

Hypoxia-selective cytotoxins drugs

In Vitro Profiling Drug Activity, Selectivity and Liability

Kinetics controlling bioreductive drug selectivity towards hypoxic cells

Look up the names of both individual drugs and their drug groups to access full information Selective serotonin re-uptake inhibitors (

Lung Model Selection for Drug Absorption Studies

Medication errors drug selection

Membranes drug design selectivity

National drug policies selection

Nonsteroidal anti-inflammatory drugs selective

Nonsteroidal anti-inflammatory drugs selective cyclooxygenase-2 inhibitors

Predicting Selectivity and Druggability in Drug Discovery

Pregnancy drug selection

Pulmonary drug delivery selectivity

Quantitative structure-activity relationships selective drug design

SELECTED DRUGS AND THEIR MECHANISMS OF ACTION

Selected Drugs from Early Recorded History

Selected Examples of Drug Action at some Common Target Areas

Selected drug transporters

Selected drug transporters INDEX

Selecting a Receptor Appropriate for Drug Design

Selection drug factors

Selection of Drugs

Selection, natural product drug

Selection, natural product drug development

Selective Drug Delivery for the Treatment of Other Hepatic Disorders

Selective delivery of drugs

Selective drugs, activity toward

Selective drugs, activity toward receptors

Selective estrogen receptor modulators drugs

Selective serotonin reuptake inhibitors drug administration

Selective serotonin reuptake inhibitors drug interactions

Selective serotonin reuptake inhibitors drug overdose

Selective serotonin reuptake inhibitors drug withdrawal

Selective serotonin reuptake inhibitors drugs

Selective toxicity antifungal drugs

Selective toxicity antiparasite drugs

Selective toxicity antiviral drugs

Selectivity drug design

Selectivity, drug

Selectivity, drug

Serotonin reuptake inhibitors, selective interaction with other drugs

Solubility candidate drug salt selection

Stability candidate drug salt selection

Target-selective drug design

Therapeutic range selected drugs

Tumour-selective drug delivery

Using Drug Resistance as a Selection Technique

Wrapping as a Selectivity Filter An Exercise in Drug Design

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