Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Candidate drug selection lead identification

High-throughput drug-like property profiling is increasingly used during lead identification and candidate selection. HTS pharmaceutical profiling may include ... [Pg.20]

DOS seems mainly important for lead identification. Based on the lead structure, additional structural complexity can be introduced in a direct manner by generating focused libraries. For the synthesis of complex molecules, total synthesis as it exists today and the development of selective reactions that accompany, it remain of major importance. Even in case of the successful identification of advanced leads or drug candidates from DOS, an efficient total synthesis is always required in order to provide sufficient amounts of a limited set of derivatives for detailed medicinal chemistry studies up to clinical trials. [Pg.156]

See other pages where Candidate drug selection lead identification is mentioned: [Pg.235]    [Pg.192]    [Pg.266]    [Pg.209]    [Pg.22]    [Pg.407]    [Pg.266]    [Pg.103]    [Pg.296]    [Pg.28]    [Pg.726]    [Pg.181]    [Pg.22]    [Pg.102]    [Pg.49]    [Pg.121]    [Pg.277]    [Pg.183]    [Pg.116]    [Pg.657]    [Pg.58]    [Pg.445]    [Pg.410]    [Pg.115]    [Pg.321]    [Pg.375]    [Pg.321]    [Pg.366]    [Pg.169]    [Pg.27]    [Pg.351]    [Pg.589]    [Pg.114]    [Pg.228]    [Pg.288]    [Pg.312]    [Pg.341]    [Pg.184]    [Pg.247]    [Pg.535]    [Pg.837]    [Pg.146]    [Pg.1968]    [Pg.1362]    [Pg.1367]    [Pg.126]    [Pg.2]    [Pg.113]    [Pg.142]   
See also in sourсe #XX -- [ Pg.22 ]



SEARCH



Candidate selection

Candidates

Candide

Drug candidate selection

Drug identification

Drug lead identification

Drug selection

Lead candidate

Lead identification

Lead selection

Selectivity, drug

© 2024 chempedia.info