Dermatitis irritative

Jessner s Solution has been used for over 100 years as a therapeutic agent to treat hyperkera-totic epidermal lesions [1]. This superficial peeling agent constitutes a mixture of salicylic acid, resorcinol, and lactic acid in 95% ethanol. Jessner s solution causes loss of corneocyte cohesion and induces intercellular and intracellular edema. Jessner s typically induces wounding to the level of the papillary dermis. Historically, resorcinol (a key component of Jessner s peels) was used in concentrations of 10-50% in the early twentieth century. High concentrations of resorcinol were associated with side effects such as allergic contact dermatitis, irritant contact... 

Smith, H., Basketter, D., and McFadden, J., Irritant dermatitis, irritancy and its role in allergic contact dermatitis, Exp. Dermatol., 27, 138, 2002. 

Formaldehyde is one of the most common causes of occupational skin disease the major effects of formaldehyde on the skin are irritant dermatitis and allergic contact dermatitis. Irritant dermatitis results from direct injury to the skin and is characterized by redness and thickening of the affected areas. In more severe cases there may be blistering, scaling, and the formation of fissures. 

Unlabeled Uses Allergic contact dermatitis, irritant contact dermatitis, psoriasis... 

A deficiency of the vitamin can result in lymphopenia, convulsions, dermatitis, irritability, and nervous disorders in humans. A defidency in monkeys may cause arteriosclerosis, while in rats, acrodynia. Research indicates that all animals require vitamin Bg, Bacteria in intestines generate some of this vitamin, but relatively little is available to humans in this form. Endogenous sources are available to plants, fungi, and some bacteria. 

Squamometry X corresponds to the analytical evaluation of xerosis using SACD samplings.6,7,14 31 A linear correlation exists between the amount of harvested orthokeratotic SC and SQMI. Data are also influenced by the presence of parakeratotic cells and serum deposits as found in spongiotic dermatoses such as atopic dermatitis, irritant or allergic contact dermatitis, seborrheic dermatitis and psoriasis.32,36... 

Toxicity Picric acid causes adverse effects on the skin of animals and humans like allergies, dermatitis, irritation, and sensitization. Absorption of picric acid by the system causes headache, fever, nausea, diarrhea, and coma. In high concentrations, picric acid is known to cause damage to erythrocytes, kidney, and liver.68 69... 

Dermal Effects. Chromium compounds can produce effects on the skin and mucous membranes. These include irritation, burns, ulcers, an allergic type of dermatitis. Irritation of the nasal mucosa and other mucosal tissues of the respiratory system, and nasal septum ulcers, and perforation were considered under Respiratory Effects discussed above. Dermatitis is considered under Immunological Effects discussed below. 

Synonyms and trade names picronitric acid, 2,4,6-trinitrophenol, trinitrophenol Use and exposure Picric acid is a white to yellowish crystalline substance and highly flammable. It is used in the manufacture of fireworks, matches, electric batteries, colored glass, explosives, and disinfectants. Pharmaceutical, textile, and leather industries also make use of picric acid. Bouin s picro-formol is used as a preservative solution for biological specimens in laboratories. Toxicity and health effects Picric acid causes different adverse effects on the skins of animals and humans, like allergies, dermatitis, irritation, and sensitization. Absorption of picric acid by the system causes headache, fever, nausea, diarrhea, and coma. In high concentrations, picric acid is known to... 

Urticaria and angioedema Allergic contact dermatoconjunctivitis Allergic contact dermatitis Photoallergic contact dermatitis Irritative or toxic contact dermatitis Phototoxic dermatitis Cumulative deposition... 

K promotes normal blood clotting, dtamin B12 (cobal-amin) provides protection against pernicious anemia and mental disturbances. Vitamin can also protect against anemia as well as dermatitis, irritability, and convulsions. 

TNT stains the skin orange and yellow. It can cause dermatitis, irritation of eyes, nose, throat, and skin. High exposures may cause weakness, anemia, headaches, liver, or central nervous system damage. 

Medicines may also be exempted from POM classification if there are limitations on the use of the product. An example would be hydrocortisone cream 1% normally categorised as a POM but as a P medicine in packaging that limits the use of the cream to the treatment of allergic contact dermatitis, irritant dermatitis, insect bite reactions and mild to moderate eczema it should be applied sparingly once or twice a day for a maximum of one week. The P form or over-the-counter (OTC) form is only licensed for those indications and dosages listed above and further restriction to sales include unsuitability for OTC sale to treat ... 

Often there is a sharp cut-off point dehned by the area of contact, but in longstanding dermatitis irritation may become generalised and spread to areas not in contact with the allergen. 

Mechlorethamine hydrochloride (Mustargen) and carmustine (bischloronitrosourea, BCNU, BICNU) are used topically to treat cutaneous T-cell lymphoma. Both can be applied as a solution or in ointment form. It is important to monitor complete blood counts and liver function tests because systemic absorption can cause bone marrow suppression and hepatitis. Other side effects include allergic contact dermatitis, irritant dermatitis, secondary cutaneous malignancies, and pigmentary changes. Carmustine also can cause erythema and posttreatment telangiectasias. 

HEALTH SYMPTOMS inhalation (lacrimation, conjunctiva irritation, pulmonary changes, vomiting, bronchial or pulmonary lesions) skin absorption (vomiting, bronchitis, pulmonary edema) contact (smarting pain in the eyes, increased skin sensitivity, dermatitis, irritates mucous membranes) ingestion (severe nausea, vomiting, colic, diarrhea). 

Irritant contact dermatitis Irritant dermatitis is a nonimmunological, local inflammatory response at the site on single, repeated, or continuous contact with a chemical. It results in erythema (reddening of the skin) and edema (accumulation of fluid), which is often irregular or patchy in nature. 

Symptoms of Exposure May cause acute and moderate dermatitis irritant to eyes, skin and mucous membranes. 

As mentioned above, in the pathogenesis of contact dermatitis, irritants and allergens are simultaneously interwoven and endogenous and environmental factors are often additionally involved. This leads to overlapping categories between ICD and ACD. In practice, the... 

Basketter DA, Reynolds FS, York M (1997) Predictive testing in contact dermatitis irritant dermatitis. Clin Dermatol 15 ... 

Wilhelm KP (1995) Irritant dermatitis Experimental aspects. In Eisner P, Maibach HI (eds) Irritant dermatitis. New clinical and experimental aspects. Karger, Basel, pp 144-151 Wilhelm KP, Surber C, Maibach HI (1989) Quantification of sodium lauryl sulphate irritant dermatitis in man comparison of four techniques skin color, reflectance, transepidermal water loss, laser Doppler flow measurement and visual scores. Arch Dermatol Res 281 293-295 Wilkinson JD, Willis CM (1998) Contact dermatitis irritant. In Champion RH, Burton JL, Burns DA, Breathnach SM (eds) Textbook of dermatology, 6th edn. Blackwell, London, PP 709-731... 

It must be pointed out that the vast majority of occupational dermatoses is represented by contact dermatitis [irritant contact dermatitis (ICD), allergic contact dermatitis (ACD), immunoglobulin E (IgE)-mediated reactions] rarely, infectious dermatitis or other forms of dermatitis are encountered. 

Weltfiiend S, Ramon M, Maibach HI. Irritant dermatitis (irritation). In Zhai H, Maibach HI, editors. Dermatotoxicology. 6th ed. Boca Raton CRC Press 2004. p. 181-228. 

Exposure of a worker to pitch dust or vapour may harm the skin by causing irritation, tumour or dermatitis. Irritation is the earliest and commonest reaction, occurring after a few days or weeks of exposure and affecting the face and neck. There is complaint of itching or burning, aggravated by... 

Diagnosis. Clinical signs of chromium toxicosis include contact dermatitis, irritation of the nasal passages, and acute gastroenteritis. 

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